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Seckel Syndrome is a rare genetic disorder which causes morphological changes throughout the body. Some of the most commonly reported changes are those present within the cranium and mandible such as microcephaly, a beak-like nose with convex nasal ridge, and mandibular deformities such as micrognathia. However, these clinical terms provide insufficient information to allow for proper diagnosis or to understand the distortions in physiology that take place with the disease. Therefore, quantification of the features of the skull are necessary to further explain this pathology, and comparisons to normal variation will help to understand the degree to which the anatomy is affected. Seckel Syndrome is classified as a member of the microcephaly family of pathologies; however, our results demonstrate that the overall volume of the skull is not as significantly decreased as the cranial vault itself, which may provide the catalyst for Chiari Type I malformations. The mandible, likewise, is severely altered by Seckel Syndrome decreases in approximately 44% of its volume and demonstrating altered physical proportions. Finally, the osteological measurements of the facial features demonstrated inconsistent findings between different anatomical structures providing evidence that Seckel Syndrome may have a variable effect on the different bones and tissues of the skull.

OBJECTIVE: to verify the association between general health perceptions with a focus on sleep quality, eating activities and concentration areas of the course after university admission. METHOD: Cross-sectional study approved by ethics committee (n°2,581,563), with a sample of 432 undergraduate students from the Federal Public University, divided into three groups: Group 1: Humanities Students; Group 2: Health Students; Group 3: Exact Science students. For the collection, we used: vivências Acadêmicas’s questionnaire in the reduced version, and a sociodemographic questionnaire. Descriptive and inferential statistical techniques were used for analysis, considering a significance level of 5%. RESULTS: In the general sample, all general health perceptions were impaired after entering the University. In the analysis of the groups, it is noticed that Group 1 presented more negative rates of health perception (47.3% p (1) = 0.016), with significant and significant sleep-related impairments (68.2% p (1) = 0.002). On the other hand, the students in Group 3 presented the worst perceptions about the quality of food and difficulties in performing leisure activities (p (1) = 0.005). CONCLUSION: There was a significant association between university admission and negative health perceptions. In addition, it was found that the students in the humanities and exact areas were the most vulnerable. Thus, it can be considered that academic experience can contribute negatively to the promotion of the health of young people, and, in this sense, it is recommended the implementation of educational programs aimed at self-care, prevention of academic stress and its negative effects on health.

This article has carried on the theoretical analysis to the generation mechanism of the sliding pile phenomenon. A certain prediction was made on the causes of slipping piles and their influencing factors. At the same time, it is based on the collected field measurement data, an engineering example is selected to briefly analyze the changes in the bearing capacity of the pile foundation after the sliding pile occurs. It is found that the influence of the sliding pile on the bearing capacity of the pile foundation is mainly the influence on the side friction resistance of the pile, and the reduction of the soil resistance is also mainly due to the reduction of the side friction resistance of the pile. Finally, using ABAQUS finite element analysis software, a numerical simulation analysis was carried out on the changes of the stratum structure, the analysis results show that the position change of the soft soil layer has a certain influence on the bearing capacity of the pile, but it does not change the settlement of the pile top under the limit state; The greater the strength of the supporting layer, the greater the bearing capacity and the greater the displacement when reaching the limit state; The length of the slipped pile does not affect the bearing capacity of the pile foundation, and the farther the slipping occurs from the bearing layer, the smaller the impact on the bearing capacity of the pile foundation. Therefore, in the actual project, attention should be paid to the selection of the bearing layer and the soft soil layer close to the bearing layer should be removed to reduce the impact of the slipping pile on the bearing capacity of the pile foundation and ensure that the bearing capacity of the pile foundation meets the design requirements.

Background: Peroneal pathology, including trauma, can result in Cavovarus-Drop Foot type deformity, precluding patients from functioning in or attempting bracing. Lateral ankle stabilization and other associated procedures sometimes are not enough to address the resultant deformity, thus many CavoVarus-Dropfoot patients still have gait abnormalities, function minimally in a brace and still have secondary ambulatory pain and loss of function even when braced. We review the results of 9 patients meeting this criteria and electing for a Modified Putti Procedure and lower extremity reconstruction. Materials and Methods: The charts of 9 patients with adult-acquired CavoVarus deformity foot type after peroneal rupture were reviewed, all but 1 had failed previous AFO/bracing. These patients underwent surgical correction all consisting of the Modified Putti procedure, along with other ancillary procedures and the results and outcomes were collected. Additionally, surgical technique was documented. Results: The mean VAS score improved from 9.1 to 2.4 pre- and post-operatively, respectively. The average time to weight bearing was 7.2 weeks. Four of 9 (44.44%) patients experienced some form of complication. Eight of 9 (88.88%) patients relayed the surgery was a success and would opt to undergo it again, given the choice. Conclusion: The Modified Putti Procedure showed promising results, great patient satisfaction and marked improvement in pre-operative and post-operative pain rating. This technique, utilized after severe peroneal trauma and resultant deformity is present, is a considerable option to have in the foot and ankle surgeon’s armament.

SARS-CoV-2 (severe acute respiratory syndrome-coronavirus-2) is a novel coronavirus identified for the first time in Wuhan (China) in 2019, responsible of the current pandemic infection known as Coronavirus-19 disease (COVID-19). Wide range of clinical presentation of COVD -19 has been observed, from asymptomatic carriers to ARDS. The common signs and symptoms of SARS-CoV-2 infection include fever, fatigue, dry cough, and dyspnoea; the severity of the disease is due to the impairment of the respiratory function. The radiological findings include a large variety of lesions; bilateral interstitial pneumonia is the most concerning presentation of COVID-19. Pleural involvement has been described in a minority of cases: pleural thickening had been observed in 32% of cases whereas pleural effusion is uncommon being described in only 5%. Furthermore, pleural involvement has been significantly associated with a worse prognosis. Coronavirus 2 (SARS-CoV-2), beyond the nasopharyngeal swab, has been detected in other samples; up to now, data about RT-PCR specific results in the pleural fluid of patients suffering from coronavirus disease 2019 5 (COVID-19) are very limited. The current gold standard for diagnosis is nucleic acid detection by real time Reverse Transcriptase-Polymerase Chain Reaction (RT-PCR) in nasopharyngeal swab. In this report, a case of a positive RT-PCR for Sars-Cov-2 in the pleura fluid and in the naso- pharyngeal swab of a patient affected by bilateral interstitial pneumonia and severe respiratory failure is described. As the presence of SARS-Cov-2 in the pleural fluid seems to be associated to a poor prognosis, physicians should carry out the specific RT-PCR assay both in the nasopharyngeal swab and in the pleural sample also when the fluid amount is very scarce and not recognizable in the chest X ray. Furthermore, the analysis of multiple samples allows to increase the test reliability.

Laser in-situ keratomieleusis (LASIK) is a common intervention for young, active, ametropic individuals to improve their visual acuity. pseudo-accommodative cornea (PAC), a variant of LASIK, to correct ametropia among presbyopic patients is proven in maintaining good distant vision; yet, the satisfactory spectacle free reading vision is limited to the ageing progression. However, successful treatments do not guarantee patient’s satisfaction. Assesment of the objective topographic indicators, visual acuity, higher order abrasion, and contrast sensitivity; revealed the clarification of a mild headache as a personal subjective experience after the treatment. The role of the persistent, dominant eye, the brain perception, seems to be critical factor to a patient’s satisfaction. To a certain degree, the interplay amongst the optical part and it’s supporting tissue, within and between the eyeballs, as well as its relationship to the neurosensory parts of the visual systems after Lasik surgery have not yet been assessed and reported elsewhere.

There is a need to clarify continental formation processes and the Oklo natural nuclear reactor happens to be in the exact position where such a natural phenomena needs to be to explain continental separation. New research points of the author are shown to fit with findings of the French Commissariat à l’énergie atomique here.

The author’s works have shown in various ways the absence of dangerosity of pesticides for human health, as all the studies claiming to find effects forget the side contamination with alpha-emitting nanoparticulates (from radon, phosphated fertilizers, car fumes, coal ashes for instance) that interacts with the samples and destroys the scientific validity of the results. This paper looks at the issue of organic food in a different way, because organic food also thrives on the sheer claim that it benefits to insects, and the author’s results here show that this is not the case too.

As the United States [U.S.] nursing shortage continues, the need for a highly educated work force grows. Although, the Carnegie Report [1] advocated for a Bachelor of Science in Nursing [BSN] degree as entry into practice with a required Master of Science in Nursing [MSN] earned within 10 years, the necessity to pursue a graduate degree in nursing has not been as widely encouraged as the baccalaureate degree. Master’s prepared nurses are essential across a variety of health care settings to serve in leadership, management, and advanced primary provider positions, as well as in academic settings as faculty members and researchers. In 2017, approximately 17% of the nursing workforce held a master’s degree. This was up from 13.8% in 2013 [2]. While the percentage of nurses earning a master’s degree has risen gradually, the need for additional highly educated nurses persists as rapid advancements in health care technology, including telehealth and informatics, occur. During 2016 and 2017, the nursing program at the authors’ institution tasked the recruitment and retention committee with increasing enrollment in the graduate nursing program. The committees stated goal was increasing enrollment in all role specializations (nurse practitioner, education, and management). The committee identified two areas of particular concern: the need for family nurse practitioners in the nearby rural communities and a shortage of nursing faculty in the area as these areas had become challenging. Although the nursing program had been successful at retaining a majority of its students, recruitment of new students was challenging and thus became the key focus.

Code-Switching is a process of bilingualism that involves the alternation of two languages in the course of a single conversation as a result of language contact phenomenon. This paper is about the conjugation of the verbal forms in the switches of bilingual Songhay-French, Bamanankan-French and Fulfulde-French speakers as pointed out in several studies by I. Abdoulaye (2013, 2016), M. Minkailou and I. Abdoulaye (2016, 2018), I. Abdoulaye and M. Minkailou (2017, 2019). The main objective of the present paper is to describe the verbal paradigm in the switches of these three different groups of francophone speakers according to the existing theories and models on Code-Switching and Code-Mixing constraints. Based on the Matrix Language Frame Model of C. Myers-Scotton (1993a, b), the paper aims at proposing and analysing a francophone alternative of grammatical constraint in code switching. The study uses secondary data collected from the research works cited above in which spontaneous and fresh conversations have been recorded, transcribed and translated into English in an oral corpus. The population of these three different investigations is heterogeneous consisting of bilingual Songhay, Bamanan and Fulah civil servants and university students. Examining the nature of the switches, the study purposely focuses on the intra-sentential code-switching, in which the participants alternate the two codes, inserting words from French into their respective native languages. Analysing the inflected forms of the French verbs embedded in Songhay, Bamanankan or Fulfulde codes, the study has revealed that all the switched verbs belong to the same verb form, the French past participle of the three verb groups (first, second and third). So, the study has concluded that this way of conjugating verbs in Code-Switching is typical to francophone second language leaners. This approach in Code-Switching that the authors are proposing as the Francophone Model of Switching Verbs is a result…