Impact of components of metabolic syndrome on the prostatic volume and lower urinary tract symptoms in a sample of patient with benign prostatic hyperplasia in Iraq


Impact of components of metabolic syndrome on the prostatic volume and lower urinary tract symptoms in a sample of patient with benign prostatic hyperplasia in Iraq


Dr. Ali Zuhair Khudhur 1, Dr. Alaa Al-Deen Al-Dabbagh 2
1 Al-Yarmouk Teaching Hospital/Department of urology/Baghdad/Iraq
2 Assistant professor at Al-Mustansiriyah University/College of Medicine/Department of surgery / Baghdad / Iraq


Global Journal of Urology and Nephrology

Objective

To evaluate the  association between the components of metabolic syndrome (MetS) and lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH)  focusing at their effects on  prostatic volume   and on the severity of LUTS   .

Patients & Methods

From October 2016 to January 2018, eighty patients presented with LUTS due to the BPH. LUTS were assessed using the international prostatic symptoms score (IPSS) and MetS was defined according to the National Cholesterol Education Program-Adult Treatment Panel III guidelines. Patients were randomly collected into two categories: A (48 patients) had MetS and B (32 patients) without MetS.

Results

The mean age was 64.3 years, statistically significant variation was identified between the two categories regarding the moderate and severe IPSS, S.PSA, prostatic size and post voiding residue (PVR),  the P value (<0.05).

The most frequent MetS components were: hypertension in 65/80 patients (81.25%), high fasting glucose in 49/80 patients (61, 25%), and waist circumference elevation in 55/80 patients (68.75%).

The association between MetS components, the prostatic volume   and severity of LUTS had shown that all MetS components except HDL-cholesterol were significantly correlated with higher prostatic volume (P < 0.05). Also a positive statistically significant association was discovered between each component of MetS and higher IPSS, excepting HDL-cholesterol (P = 0.93) and triglyceride (P = 0.58).

Conclusion

The results of the present study confirmed that there is a significant relation between the components of metabolic syndrome, the increase in prostatic volume and the severity of LUTS/BPH.


Keywords: LUTS, BPH, MetS, prostatic volume

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How to cite this article:
Ali Zuhair Khudhur, Alaa Al-Deen Al-Dabbagh. Impact of components of metabolic syndrome on the prostatic volume and lower urinary tract symptoms in a sample of patient with benign prostatic hyperplasia in Iraq. Global Journal of Urology and Nephrology, 2019, 2:17. DOI: 10.28933/gjun-2019-09-1406


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