ANTIOXIDANT ACTIVITY AND HEMOTOXICITY OF MEDICINAL PLANT OF THE CAATINGA DOMAIN: AMBURANA CEARENSIS (FABACEAE)


Antioxidant Activity and Hemotoxicity of Medicinal Plant of the Caatinga Domain: Amburana Cearensis (Fabaceae)


João Victor de Oliveira Alves1*, Francisco Henrique da Silva1, Maria Victoria dos Santos Alves Evaristo2, Janderson Weydson Lopes Menezes da Silva3, Paloma Maria da Silva1, Larissa Gomes de Arruda1, Irivânia Fidelis da Silva Aguiar1, Saulo Almeida de Menezes1, Fálba Bernadete Ramos dos Anjos4, Márcia Vanusa da Silva1

1Biochemistry Department, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil; 2Graduated in Biological Sciences, Institute of Biological Cienicas, Campus Santo Amaro, Universidade de Pernambuco; 3Aggeu Magalhães Institute (IAM) – FIOCRUZ/PE, Brazil. 4Department of Histology and Embryology, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil


International Journal of Bioscience and Medicine

Amburana cearensis is a medicinal species popularly known as “cherry” or “aroma amburana” that has wide distribution in South America, being characteristic of Seasonal Forests. It also occurs in Semideciduous Seasonal Forest, restricted to rocky or limestone outcrops; in Submontane Deciduous SubmontanaSeasonalForest; in Dense Ombrophilous Forest (Atlantic Forest) and even in caatinga/dry forest. Taking into account the growing interest in the search for agents that act in the face of oxidative stress, without causing toxic effects to biological systems, the present study aimed to investigate the phytochemical composition and evaluate the antioxidant and hemotoxic activities in vitro of the aqueous extract obtained from the shells of Amburana cearensis (EAAc). Hemaglutination wasevaluated for human erythrocytes collected from people with the presence of O+ blood. In the face of the tests, Amburana cearensis presented significant results for antioxidant activity without causing erythrocyte hemolysis, highlighting the importance of the species as a source of antioxidant agents, which are recognized for blocking the evolution and acting to combat symptoms triggered by diseases associated with oxidative stress.


Keywords: Caatinga. Aqueousextract. Erythrocytes. Free radicals.

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How to cite this article:
João Victor de Oliveira Alves, Francisco Henrique da Silva, Maria Victoria dos Santos Alves Evaristo, Janderson Weydson Lopes Menezes da Silva, Paloma Maria da Silva, Larissa Gomes de Arruda, Irivânia Fidelis da Silva Aguiar, Saulo Almeida de Menezes, Fálba Bernadete Ramos dos Anjos, Márcia Vanusa da Silva1.Antioxidant Activity and Hemotoxicity of Medicinal Plant of the Caatinga Domain: Amburana Cearensis (Fabaceae) International Journal of Bioscience and Medicine, 2020; 4:13. DOI: 10.28933/ijbm-2020-07-1805


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