Paraparesis following commencement of Anti Tuberculosis drugs for latent Tuberculosis. Case report and review of literature

Paraparesis following commencement of Anti Tuberculosis drugs for latent Tuberculosis. Case report and review of literature

Danish Waqar1 and Mohamed A Yassin2

1.Department of Medical Education, Hamad Medical Corporation
2.Deaprtment of Medical Oncology NCCCR,Hamad Medical Corporation

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A 43 year old female Patient, with recently diagnosed latent Tuberculosis (TB), started On anti – TB drugs (Isoniazid, Rifampicin), came with symptoms of Motor and sensory polyneuropathy only 4 weeks after starting the drugs. Extensive investigations were pursued. Nerve conduction study showed Features of Guillain – Barre syndrome (GBS). After stopping the Anti TB medications, patient symptoms Improved. This gives us an idea that Anti TB medications can itself trigger GBS. The Association of TB and GBS will be reviewed in Literature as well as the differentials and management.

Keywords: Paraparesis, Anti Tuberculosis drugs, latent Tuberculosis, Case report

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How to cite this article:
Danish Waqar and Mohamed A Yassin. Paraparesis following commencement of Anti Tuberculosis drugs for latent Tuberculosis. Case report and review of literature. International Journal of Case Reports, 2018 3:44. DOI:10.28933/ijcr-2018-10-2408

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