A Rare Reason of Ileus: Atypical Hemolytic Uremic Syndrome


A Rare Reason of Ileus: Atypical Hemolytic Uremic Syndrome

Eray Eroglu1, Aysenur Cirak2, Ismail Kocyiğit1, Kemal Deniz3, Murat Hayri Sipahioglu1, Bulent Tokgoz1, Oktay Oymak1

1Erciyes University School of Medicine,Department of Nephrology, Kayseri,Turkey
2Erciyes University School of Medicine, Department of Internal Medicine, Kayseri,Turkey
3Erciyes University School of Medicine,Department of Pathology, Kayseri,Turkey


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Hemolytic uremic syndrome (HUS) is a thrombotic microangiopathy that is characterized by intravascular hemolytic anemia, thrombocytopenia and acute renal failure. Typical form occurred with the shiga-like toxin produced by Escherichia coli bacterium or Shigella dysenteriae bacterium while atypical HUS is sporadic or familial form of the disease which develops due to uncontrolled activation in alternative complement pathway. It may present with recurrent attacks and it has a potential of poor prognosis. In this case report we presented a 36-year-old woman in her 22nd week pregnancy without any history of chronic disease or medication whom admitted to hospital with abdominal pain, bloody diarrhea, oliguria and diagnosed with atypical HUS. She was diagnosed with ileus at the first month of Eculizumab treatment and a polyploid lesion obstructing the lumen of the colon was detected. Pathologic examination of the mass revealed a chronic active inflammatory lesion.


Keywords: Atypical HUS, Pregnancy, Eculizumab, Ileus


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How to cite this article:
Eray Eroglu, Aysenur Cirak, Ismail Kocyiğit, Kemal Deniz, Murat Hayri Sipahioglu, Bulent Tokgoz, Oktay Oymak. A Rare Reason of Ileus: Atypical Hemolytic Uremic Syndrome. International Journal of Case Reports, 2018 3:47. DOI:10.28933/ijcr-2018-11-1501


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