The diagnostic conundrum posed by Hypereosinophilia with a foot drop: A Case Report


The diagnostic conundrum posed by Hypereosinophilia with a foot drop: A Case Report


Jonathan Moriarty1, Natassja Moriarty 1, Anthony Macheta2, Fiona Wood3

1Department of Medicine, Department of Furness General Hospital; 2Department of Haematology, Furness General Hospital; 3Department of Rheumatology, Furness General Hospital


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We present a case of an 81-year-old asthmatic female with a left foot drop and an incidental finding of hypereosinophilia with an initial differential diagnosis of Eosinophilic Granulomatosis with Polyangiitis (EGPA). However, after extensive investigations, all causes of hypereosinophilia were excluded and the left foot drop was secondary to a radiculopathy. This led to a diagnosis of Idiopathic Hypereosinophilic Syndrome (IHES), a diagnosis of exclusion. This is the first case report where hypereosinophilia and a left foot drop where unrelated conditions occurring simultaneously thus posing a diagnostic dilemma. Therefore, this case report aims to highlight the importance of a systematic approach in the investigation of hypereosinophilia, to ascertain the cause and to rule out organ damage as this will affect the management and the outcome.


Keywords: Idiopathic Hypereosinophilic syndrome, Hypereosinophilia, Eosinophilic Granulomatosis with Polyangiitis, case report


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How to cite this article:

Jonathan Moriarty, Natassja Moriarty, Anthony Macheta, Fiona Wood. The diagnostic conundrum posed by Hypereosinophilia with a foot drop: A Case Report. International Journal of Case Reports, 2020 4:136. DOI: 10.28933/ijcr-2020-05-2105


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