Atypical Presentation of Renal Cell Carcinoma in a 47-year Old Hypertensive Female Patient – Case Report


Atypical Presentation of Renal Cell Carcinoma in a 47-year Old Hypertensive Female Patient – Case Report


Mihai Gherman1, Anca Madalina Sere2, Ioana Duca3

1”Iuliu Hațieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania
2”Iuliu Hațieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania
32nd Internal Medicine Department, County Emergency Hospital Cluj-Napoca,”Iuliu Hațieganu” Uni-versity of Medicine and Pharmacy, Cluj-Napoca, Romania


International-Journal-of-Case-Reports-2d code

Characterized by a wide range of nonspecific symptoms, renal cell carcinoma tends to be found only at advanced stages or when kidney failure occurs.
In this case report we describe the incidental finding of a 6 cm renal cell carcinoma in a 47-years old hypertensive female patient with peculiar symptomatology. Contrast-enhanced-US showed supplementary intratumoral necrotic areas rising the suspicion of renal carcinoma, which was confirmed by CT and histology. Incidental detection rate of renal masses has increased, ultrasound, and especially contrast-enhanced-US having an important role in its diagnosis.


Keywords: Renal carcinoma, contrast-enhanced-ultrasound, paraneoplastic


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How to cite this article:

Mihai Gherman, Anca Madalina Sere, Ioana Duca. Atypical Presentation of Renal Cell Carcinoma in a 47-year Old Hypertensive Female Patient – Case Report. International Journal of Case Reports, 2020 4:145. DOI: 10.28933/ijcr-2020-06-2505


References:

1. Scelo G, Larose TL. Epidemiology and Risk Factors for Kidney Cancer. J Clin Oncol, 2018; 36: 3574-3581.
2. Koul H, Huh J-S, Rove KO, et al. Molecular aspects of renal cell carcinoma: a review. Am J Cancer Res, 2011; 1: 240-254.
3. Low G, Huang G, Fu W, Moloo Z, Girgis S. Review of renal cell carcinoma and its common subtypes in radiology. World journal of radiology, 2016; 8: 484-500.
4. Moch H. WHO-ISUP-Graduierungssystem für Nierenkarzinome. Der Pathologe, 2016; 37: 355-360.
5. Capitanio U, Bensalah K, Bex A, et al. Epidemiology of Renal Cell Carcinoma. Eur Urol, 2019; 75: 74-84.
6. Delahunt B, Eble JN, Egevad L, Samaratunga H. Grading of renal cell carcinoma. Histopathology, 2019; 74: 4-17.
7. Piscaglia F, Nolsøe C, Dietrich CF, et al. The EFSUMB Guidelines and Recommendations on the Clinical Practice of Contrast Enhanced Ultrasound (CEUS): Update 2011 on non-hepatic applications. Ultraschall in Med, 2012; 33: 33-59.
8. Lopez-Beltran A, Carrasco JC, Cheng L, Scarpelli M, Kirkali Z, Montironi R. 2009 update on the classification of renal epithelial tumors in adults. Int J Urol, 2009; 16: 432-443.
9. Gild P, Ehdaie B, Kluth LA. Effect of obesity on bladder cancer and renal cell carcinoma incidence and survival. Current Opinion in Urology, 2017; 27(5): 409-414.
10. Pruijm M, Hofmann L, Vogt B, et al. Renal Tissue Oxygenation in Essential Hypertension and Chronic Kidney Disease. Int J Hypertens, 2013 Feb 20; doi: 10.1155/2013/696598.
11. Gonzalez HC, Lamerato L, Rogers CG, Gordon SC. Chronic Hepatitis C Infection as a Risk Factor for Renal Cell Carcinoma. Dig Dis Sci, 2015; 60: 1820-1824.
12. Choueiri TK, Je Y, Cho E. Analgesic use and the risk of kidney cancer: A meta-analysis of epidemiologic studies. Int J Cancer, 2014; 134: 384-396.
13. Karami S, Daugherty SE, Purdue MP. A prospective study of alcohol consumption and renal cell carcinoma risk. Int J Cancer, 2015; 137: 238-242.
14. Yosipovitch G. Chronic pruritus: a paraneoplastic sign. Dermatol Ther 2010; 23: 590-596.
15. Murtaza B, Hichami A, Khan AS, Ghiringhelli F, Khan NA. Alteration in Taste Perception in Cancer: Causes and Strategies of Treatment. Front Physiol, 2017; 8: 134-134.