Paget´s disease of bone in a patient on peritoneal dialysis

Paget´s disease of bone in a patient on peritoneal dialysis

Flores-Padilla Guillermo1,2, Solis Jose Gabriel1,3*, Zavala-Jonguitud Luis Fernando1,4, Juarez-Villa Daniel1,5, Olascoaga-Lugo Arturo1,6

1Department of Internal Medicine, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social. México City, México. Adress: Avenida Cuauhtémoc # 330 Colonia Doctores. Alcaldía Cuauhtémoc. Ciudad de México 06725. México. 2ORCID ID: 3ORCID ID: 4ORCID ID: 5ORCID ID: 6ORCID ID:

Paget´s disease of bone is a disorder characterized by disorganized bone remodeling. It´s occurrence in patients with end-stage kidney disease on renal replacement therapy is rare. Here we report a case of Paget´s disease of bone in an 80-year-old male on peritoneal dialysis that presented a high level of alkaline-phosphatase with a mildly elevated parathyroid hormone level and typical imaging findings localized to the pelvis. This is the fourth reported case of Paget´s disease in a patient on peritoneal dialysis and the first treated with denosumab.

Keywords: Paget disease of bone; kidney failure; peritoneal dialysis; denosumab

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Flores-Padilla Guillermo, Solis Jose Gabriel, Zavala-Jonguitud Luis Fernando, Juarez-Villa Daniel, Olascoaga-Lugo Arturo. Paget´s disease of bone in a patient on peritoneal dialysis. International Journal of Case Reports, 2021; 5:196. DOI: 10.28933/ijcr-2021-01-2205


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