Prostate stromal tumour: case reports and review of literature


Prostate stromal tumour: case reports and review of literature


Odusanya Benjamin O.1*, Saliu Abdulwaid N.2, Oyewole Olugbenga O.3, Mabadeje-Isowo Bilikisu A.4, Nwamannah Faith O.5

1Senior clinical fellow, Urology department, Manchester University NHS Foundation Trust. 2Consultant urologist, Department of Surgery, General Hospital, Marina, Lagos. 3Consultant Pathologist, Department of Pathology, General Hospital, Marina, Lagos. 4Consultant radiation and clinical oncologist Department of Surgery, General Hospital, Marina , Lagos. 5House officer, Department of Surgery, General Hospital, Marina, Lagos.


Background

Prostate cancer is a common malignancy in men; however, sarcoma of the prostate is an uncommon variant. Sarcoma of the prostate occurs in all age groups with rhabdomyosarcoma being more common in children while leiomyosarcoma occurs more in the older adults. Stromal tumour of uncertain malignant potential (STUMP) occurs in adults. Modalities of treatment include surgery, radiotherapy and chemotherapy used singly or in combination, but all report poor long term survival despite treatment selected. We present 2 cases of prostate stromal tumours.

Case report

We present two patients in their fourth decade who presented with acute urinary retention. Computed tomography scan was performed in both cases and showed a large tumour arising from the prostate. Prostate specific antigen was less than 4ng/ml in the two cases and core needle biopsy performed and samples taken for histology. The histology reports showed embryonal carcinoma and STUMP in the first and second cases respectively.

Conclusion

Prostate sarcomas are uncommon but may pursue aggressive clinical course while STUMP has a variable course. Early diagnosis and use of combined modalities of treatment may be required to improve survival.


Keywords: Sarcoma; Stromal tum-our; Prostate cancer; STUMP


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How to cite this article:

Odusanya Benjamin O., Saliu Abdulwaid N., Oyewole Olugbenga O.,Mabadeje-Isowo Bilikisu A., Nwamannah Faith O.. Prostate stromal tumour: case reports and review of literature. International Journal of Case Reports, 2021; 5:215. DOI: 10.28933/ijcr-2021-04-2105


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