Merkel Cell Carcinoma of Anal Canal: Case Report and Literature Review

Merkel Cell Carcinoma of Anal Canal: Case Report and Literature Review

Zahrh F Abualsaud1, Zahra F Alkhunaizi2, Mohammed Somali2, Amani Joudeh2, Mohammed Tahtouh1

1Dept of General Surgery, King Fahad Specialist Hospital Dammam, Saudi Arabia;
2Dept of Pathology, King Fahad Specialist Hospital Dammam, Saudi Arabia

Few cases of anal canal Merkel cell Carcinoma have been reported in the literature. Merkel Cell Carcinoma is rare neuroendocrine tumor which commonly found in sun-exposed areas such as extremities. We describe a case of 74-year-old male with anal canal Merkel Cell Carcinoma. He presented with peri-anal pain, tenesmus and itching. Besides, he was found to have chronic anemia. An anal nodule was found during per-rectum physical examination that was excised during endoscopy. Histological examination of the nodule confirmed the diagnosis of Merkel Cell Carcinoma. Thenceforward, patient died 7 months after diagnosis with marked metastatic disease despite initiation of Pembrolizumab therapy.

Keywords: Anal canal; Merkel cell carcinoma; Neuroendocrine tumors; MCC

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Zahrh F Abualsaud, Zahra F Alkhunaizi, Mohammed Somali, Amani Joudeh, Mohammed Tahtouh.Merkel Cell Carcinoma of Anal Canal: Case Report and Literature Review. International Journal of Case Reports, 2021,5:245. DOI: 10.28933/ijcr-2021-08-2905


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