Case Report of International Journal of Case Reports
The Interesting Link Between Neurocysticercosis and Glioblastoma in a 41-year-old Hispanic Female
Teresita Gonzalez MD1, Pyi Phyo Aung MD1, Atif Hussein MD2
1 Department of Medicine, Memorial Healthcare System, Hollywood, FL
2 Department of Hematology – Oncology, Memorial Cancer Institute, Hollywood, FL
Neurocysticercosis (NC) is a common condition worldwide while glioblastoma is the most common brain cancer among adults but overall, a rare disease. NC is the most common cause of seizures in developing countries. Although no causal relationship is established, there have been an association previously reported between NC and glioblastoma. Here we present a case of a 41-year-old female who was diagnosed with NC, treated with antiparasitic medications who developed worsening neurologic deficits despite treatment, and was subsequently diagnosed with a large left frontotemporal mass consistent with glioblastoma. Patient then underwent treatment with concurrent radiation and temozolomide.
Keywords: Neurocysticercosis; Glioblastoma
How to cite this article:
Teresita Gonzalez, Pyi Phyo Aung, Atif Hussein. The Interesting Link Between Neurocysticercosis and Glioblastoma in a 41-year-old Hispanic Female. International Journal of Case Reports, 2021; 5:255. DOI: 10.28933/ijcr-2021-11-0705
1. Carabin H, Ndimubanzi P, Budke C, Nguyen H, Qian Y, Cowan L et al. Clinical Manifestations Associated with Neurocysticercosis: A Systematic Review. PLoS Neglected Tropical Diseases. 2011;5(5):e1152.
2. Carabin H, Ndimubanzi P, Budke C, Nguyen H, Qian Y, Cowan L et al. Clinical Manifestations Associated with Neurocysticercosis: A Systematic Review. PLoS Neglected Tropical Diseases. 2011;5(5):e1152.
3. Wen P, Weller M, Lee E, Alexander B, Barnholtz-Sloan J, Barthel F et al. Glioblastoma in adults: a Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future directions. Neuro-Oncology. 2020;22(8):1073-1113.
4. Gonzales I, Rivera J, Garcia H. Pathogenesis ofTaenia soliumtaeniasis and cysticercosis. Parasite Immunology. 2016;38(3):136-146.
5. Chang A, Miska J, Wainwright D, Dey M, Rivetta C, Yu D et al. CCL2 Produced by the Glioma Microenvironment Is Essential for the Recruitment of Regulatory T Cells and Myeloid-Derived Suppressor Cells. Cancer Research. 2016;76(19):5671-5682.
6. Alibek K, Kakpenova A, Baiken Y. Role of infectious agents in the carcinogenesis of brain and head and neck cancers. Infectious Agents and Cancer. 2013;8(1).
7. Del Brutto O, Dolezal M, Castillo P, Garcı́a H. Neurocysticercosis and Oncogenesis. Archives of Medical Research. 2000;31(2):151-155.
8. Del Brutto O, Nash T, White A, Rajshekhar V, Wilkins P, Singh G et al. Revised diagnostic criteria for neurocysticercosis. Journal of the Neurological Sciences. 2017;372:202-210.
9. Kumar N, Bhattacharya T, Kumar R, Radotra B, Mukherjee K, Kapoor R et al. Is neurocysticercosis a risk factor for glioblastoma multiforme or a mere coincidence: A case report with review of literature. Journal of Neurosciences in Rural Practice. 2013;04(01):67-69.
10. Abou-Ghazal M, Kong L, Reina-Ortiz C, Yang D, Wei J, Qiao W et al. The Role of Tregs in Human Glioma Patients and their Inhibition with a Novel STAT-3 Inhibitor. Neurosurgery. 2008;62(6): 1423.
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