A rare case of cholecystitis and intra-hepatic collections associated with Methicillin-Resistant Staphylococcus Aureus bacteraemia

A rare case of cholecystitis and intra-hepatic collections associated with Methicillin-Resistant Staphylococcus Aureus bacteraemia

Jacqueline Kim Nguyen¹, BBMED, MD; Reuben J. Chen¹, MBBS, MSC; Henry To^{1, 2}, PhD, FRACS

¹Department of General Surgery, Werribee Mercy Hospital, Melbourne, Victoria, Australia; ² University of Melbourne, Department of Medicine Dentistry and Health Science, Parkville, Victoria Australia

Methicillin-Resistant Staphylococcus Aureus (MRSA) bacteraemia is associated with high morbidity and mortality. Early identification of a source of infection is critical for appropriate management. MRSA infection can affect any organ system, however infection of the biliary tract is a rare phenomenon. We report on a 67-year-old male who presented with atypical cholecystitis, intra-hepatic collections and MRSA bacteraemia. The patient was managed on a long course of antibiotics following cholecystectomy and surgical drainage of the collections. Our case highlights the importance of considering biliary sepsis as a potential source for MRSA bacteraemia, in order to expedite source control and prevent intra-hepatic abscess formation.

Keywords:  cholecystitis and intra-hepatic collections; Methicillin-Resistant Staphylococcus Aureus bacteraemia

Free Full-text PDF

How to cite this article:

Jacqueline Kim Nguyen, Reuben J. Chen, Henry To. A rare case of cholecystitis and intra-hepatic collections associated with Methicillin-Resistant Staphylococcus Aureus bacteraemia. International Journal of Case Reports, 2022, 6:262. DOI: 10.28933/ijcr-2021-12-2505

References:

1. Siddiqui AH, Koirala J. Methicillin Resistant Staphylococcus Aureus. StatPearls. Treasure Island [FL]2021.
2. Nepal SK, Giri S, Panday K. Successful treatment of methicillin-resistant Staphylococcus aureus bacteraemia and cholecystitis. BMJ Case Rep. 2012;2012.
3. Katabathina VS, Zafar AM, Suri R. Clinical Presentation, Imaging, and Management of Acute Cholecystitis. Tech Vasc Interv Radiol. 2015;18[4]:256-65.
4. Merchant SS, Falsey AR. Staphylococcus aureus cholecystitis: a report of three cases with review of the literature. Yale J Biol Med. 2002;75[5-6]:285-91.
5. Yu ATH, Cun T, Benamu E, Renault C. Persistent bacteraemia caused by Staphylococcus aureus in the gall bladder. BMJ Case Rep. 2017;2017.
6. Kim J, Gregson DB, Church DL. A case of acute cholecystitis caused by methicillin-resistant Staphylococcus aureus in an immunocompromised patient. Can J Infect Dis Med Microbiol. 2011;22[1]:e7-9.
7. Martin J, Miller D, Menard GE. Treatment considerations for recurrent MRSA bacteremia leading to cholecystitis. J Gen Intern Med. 2011;26[6]:669-72.
8. Kobayashi SD, Malachowa N, DeLeo FR. Pathogenesis of Staphylococcus aureus abscesses. Am J Pathol. 2015;185[6]:1518-27.
9. Nyabera A, Shaban L, Hijazin K, Tumarinson T. Community-Acquired Methicillin-Resistant Staphylococcus Aureus Hepatic Liver Abscess. Cureus. 2021;13[1]:e12560.