Case Study of Gabapentin Induced Exfoliate Dermatitis

Case Study of Gabapentin Induced Exfoliate Dermatitis

Katla Swapna, Mounika, Nishad Unissa

Department of Pharma. D, Bharat Institute of Technology-Pharmacy, Mangalpally, Ibrahimpatnam, KIMS, Telangana 501510, India.

 International Journal of Hospital Pharmacy

OBJECTIVE : To report a case of possible Gabapentin-induced Exfoliate Dermatitis
CASE SUMMARY : A 62 old male patient with the chief complaints of rash since 10 days . He was on treatment with Gabapentin and Pregabalin for paraesthesias by neurosurgeon from last month. Developed rash all over the body since 10 days. Past history includes similar rashes due to Diclofenac. No history of Psoriasis/eczema/no history of weight loss/cough/blood in stools. On examination patient has generalised scaling over background of erythema all over the body, exfoliation with rise of temperature. This presentation is consistent with the features of Exfoliative Dermatitis. Resolution of the clinical manifestations was observed after discontinuation of the drug; all other drugs, infections, or immunologic disorders that could have caused this syndrome were carefully excluded. An objective causality assessment revealed that exfoliative dermatitis was possibly associated with the use of Gabapentin.
CONCLUSIONS: Although Gabapentin administration seems to be the underlying cause of the Exfoliative Dermatitis observed in our patient, establishment of a definite causal relationship requires additional cases and supportive data.

Keywords: Exfoliative dermatitis, Erythema multiforme

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How to cite this article:
Katla Swapna, Mounika, Nishad Unissa. Case Study of Gabapentin Induced Exfoliate Dermatitis. International Journal of Hospital Pharmacy, 2019,4:30.


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