International Journal of Hospital Pharmacy

  • Summary of the Clinical Pharmacist’s Role in the Management of Acute Pancreatitis: A Clinical Review

    Introduction: The role of the clinical pharmacist in the management of acute pancreatitis has not been researched extensively, and only a few published studies on the topic can be found. This clinical review presents all pertinent published data and serves as a guide for clinical pharmacists who participate in the management of patients with acute pancreatitis. Methods: An extensive literature search was conducted on PubMed from 1990 to 2021 to retrieve relevant studies focusing on the role of the clinical pharmacist in the treatment of acute pancreatitis. Results: An analysis of the medications that are associated with acute pancreatitis is presented, highlighting the responsibility of the pharmacist to conduct a thorough medication investigation in order to identify a possible drug-induced acute pancreatitis. Medical management of acute pancreatitis, mainly fluid therapy, is an area where a clinical pharmacist can appropriately intervene. Proper choice of fluid therapy and its rate, nutritional considerations, pain management and antibiotic use, are all important to consider for a successful treatment with minimal adverse effects. It is well documented in the literature that clinical pharmacists can decrease hospital costs. Discharge counseling performed by a clinical pharmacist has been shown to increase patient compliance and decrease both readmission rates and follow-up physician visits. Conclusion: The clinical pharmacist, as the primary drug expert, can identify medication-induced pancreatitis, diminish the use of unnecessary antibiotics, improve patient care and decrease the overall costs.

  • Antibotics Which Distrbuted in the Hospital of Al Wahda (Derna, Libya) by Medical Supply Ward for 3 Months and Their Relations With Number of Patients Admitted and Compare These Antibiotics With Bacterial Culture Results Done by Laboratory

    Antimicrobial resistance (and particularly antibiotic resistance) is spreading now, and there are few prospects for the development of new classes of antibiotics in the short term. However, there is today considerable awareness of the need for, and political support for, action to combat Antimicrobial resistance1. Surveillance of antimicrobial use tracks how and why antimicrobials are being used and misused by patients and healthcare providers. Monitoring antimicrobial prescription and consumption behavior provides insights and tools needed to inform therapy decisions, to assess the public health consequences of antimicrobial misuse, and to evaluate the impact resistance containment interventions2. And all reports from WHO tell us about post antibiotics era that will be start if we don’t work quickly on antibiotics resistance by all efforts and due to situations of my country in Libya now need a lot of studies to decrease corruption in budgets put for health sector. Experimental methods: Study made by pilot method and we depend on data collected from dispensing papers of medical supply ward in Al Wahda hospital. *medical statistics office of Al Wahda hospital *Al Wahda hospital laboratory. *data collected to 3 months and 477 in- patient of wahda hospital. Results and discussion: After collect data from dispensing paper that based on treatment chart, we covered 477 patients for 3 months by 2169 ceftri-702 gent-1360 aug-547 cefot-23amik. And we notice percentage of higher antibiotics use was ceftriaxone equal to 45.18 % of totality and use of broad antibiotics rather than narrow antibiotics by 84.9% ,and in all principles of clinical pharmacology direct to use narrow firstly plus first line antibiotics therapy as shown in figure 1,2 respectively. And the percentage of patients those received antibiotics that Available in hospital from all patients was 25.3% ,we found that the most higher antibiotic sensitive to bacteria was CIPRO and…

  • PASS Protocol Fever as basis of COVID-19 testing in Patient- A Union Therapy Initiative

    Fever is the sole symptomatic measurement modality for Covid-19 screening which could be implemented easily all over the globe in with optimal utilization of resources. Being easy economical and easily reproducible, this has a potential to be a gold standard as well as simplicity of the procedure could help in its monitoring by patients itself and would operate an important element of patient involvement in treatment and would help in adherence in countries where health care staff are short and patient burden is high. This protocol will extend helping hands to health care worker and will involve patient participation in the treatment also.

  • Guidelines for Safe and Effective Use of Hydroxychloroquine in COVID-19 Patients

    The emergent need to treat COVID-19 patient must be tempered with safe use of drugs. The guideline set forth provides parameters for dosing and monitoring hydroxychloroquine in this population, reducing the occurrence of adverse effects and improving overall pharmacotherapy.


    Rationality is not a phenomena restricted to drugs It is also included in behavioral, psychological mythological spiritual and religious elements. Every aspect of health as per WHO health definition affects the treatment process of illness to restore health. This review is based on rationality as per the union therapy concept/ Sayojyachikitsa which aims to integrate various aspects of rationality and aims to integrate supernatural mythological and scientific aspects of rationality and devised 15 R to make treatment comprehensively holistic. This would make therapy accessible acceptable on global scale. This would help to use drugs in COVID -19 threat where in addition to clinical elements behavioral, psychological mythological spiritual and religious elements of rational drug use can play a vital role.


    Introduction: The pharmacist’s role in pharmaceutical care occurs especially in two axes: medication management and pharmaceutical care. Direct patient care is a challenge for the Brazilian health system, as this context provokes the construction of a new professional identity of the pharmacist: the clinic. Objective: To analyze a current panorama of the role of pharmaceutical professionals in primary health care. Methodology: This was a descriptive and exploratory literature review study with a qualitative approach. The descriptors “primary care”, “pharmacist” and “pharmaceutical care” were used, searched in an integrated way in the Scielo and Medline database. Results: The pharmacist still has a relevant role in management, but increasingly the system encourages the pharmacist to a more inclusive approach to patient care. There is consensus among the authors that the low number of pharmacists in primary care, coupled with the lack of perception of these professionals as part of the team and the lack of clarity about their attributions, contribute to the lack of recognition of this professional in the field of clinical practice. Conclusion: The incorporation of pharmaceutical clinical services has been shown to be an important strategy for resignification of the pharmacist in primary care. Actions involving clinical services need to be developed more frequently, so that the patient care bias is as explicit as the bureaucratic bias of pharmaceutical care.

  • Nimesulide-induced Fixed Drug Eruption

    Nimesulide is a cyclooxygenase (COX) inhibitor with a high degree of selectivity to COX-2. Nimesulide is a nonsteroidal anti-inflammatory agent with antipyretic and analgesic properties. It is being commonly prescribed in India.[1] Some of the side effects reported with its use are Pruritus, urticaria, purpura, maculopapular rash and localized toxic pustuloderma.[2],[3] Due to severe hepatotoxicity and hemolytic anemia associated with its use, Nimesulide is likely to be withdrawn from the market in many countries. Case report: The authors report a case of a patient with a history of antihistamine hypersensitivity that developed a bullous form of pigmented fixed drug eruption after Nimesulide. Patch tests performed on residual skin lesion were positive to Nimesulide, confirming that this was the culprit drug.

  • A Comprehensive Review of Clinical Pharmacists in Chronic Care Management

    Pharmacy practice has changed substantially in recent years. The professionals have the opportunity to contribute directly to patient care in order to reduce morbimortality related to medication use, promoting health and preventing diseases. Healthcare organizations worldwide are under substantial pressure from increasing patient demand. Unfortunately, a cure is not always possible particularly in this era of chronic diseases, and the role of physicians has become limited to controlling and palliating symptoms. The increasing population of patients with long-term conditions are associated with high levels of morbidity, healthcare costs and GP workloads. Clinical pharmacy took over an aspect of medical care that had been partially abandoned by physicians. Overburdened by patient loads and the explosion of new drugs, physicians turned to pharmacists more and more for drug information, especially within institutional settings. Once relegated to counting and pouring, pharmacists headed institutional reviews of drug utilization and served as consultants to all types of health-care facilities. In addition, when clinical pharmacists are active members of the care team, they enhance efficiency by: Providing critical input on medication use and dosing. Working with patients to solve problems with their medications and improve adherence.

  • Union Therapy- a Weapon Against Covid 19

    Illness and diseases has inflicted humans since ancient times through the course of development1.They emerged in Africa and initially were hunters and gatherers who learned many things from nature in terms of food shelter medicine and living. The nomadic life led to higher mortalities to them hence as a fact they started worshiping the forces of nature like sun water etc.2-4. With advancement of time and through wisdom acquired from the observations and knowledge through peer’s ancestors they stared farming and as a fact started to live in settled communities near river banks or water source. The role of their ancestors in shaping their customs and beliefs led to allot them the space of deities or as a connection link between deities. This settlement led the foundation of religions and development of civilizations. The civilizations holds their customs and beliefs which were centered over the idea of a supreme deity or supernatural power which governs all and prayers were offered to them for solutions of issues which were regarded as wrath of the God. Even sacrifices included with norms were also conducted in different cultures. In some instances body organ images were dedicated to Gods for treatment. and different deities were worship for safeguarding health. Traditional knowledge of medicines in different cultures also witnessed a transition from oral transmission to documented texts to development and integration with modern science. During course of time there has been many instances of integration which correlates with similarities irrespective of their individual inherent uniqueness in the various medical systems followed like links between Ayurveda and Sidhha, Ayurveda and TCM, TCM and Korean medicine, Buddhist medicine and Ayurveda Unani and other contemporary medicines were found. 5-10. But still in spite of similarities they are being practiced as separate entities as a result many diseases are…

  • Healthcare professionals’ awareness towards drug-drug interaction in Ayder comprehensive specialized hospital Mekelle, Ethiopia

    Background: Healthcare professionals are the most responsible body to identify potential interaction of drugs that are prescribed as well as those that the patient may be self-administering. However, awareness of healthcare professionals towards drug-drug interaction is poor. So to improve patient medication safety, it is important to assess healthcare professionals’ knowledge pertaining to drug-drug interactions and common drug-drug interactions information sources. Method: Cross-sectional study design was employed. Self-administered questionnaire was prepared to assess healthcare professionals’ knowledge of drug-drug interactions and usual sources of drug-drug interaction information. Participants were asked to classify 10 drug pairs as ‘contraindicated’, ‘can be used with monitoring’, ‘no interaction’ and ‘not sure’. Study was conducted from November 2017 to June 2018. Participants were selected using simple random sampling method. Data were analyzed using statistical software, SPSS for windows version 20. The relationship between knowledge and independent variables (age, sex, profession, work experience, training, familiarity with standard treatment guideline perception and source of information) was assessed using binary logistic regression analysis (Crude and adjusted Odds ratio, 95% confidence interval). Result: The study was done by enrolling 293 healthcare professionals among whom 46 were Physician, 31 Pharmacist, and 216 Nurses. Over all, healthcare professionals in Ayder Comprehensive Specialized Hospital had low score (24.29%) knowledge of drug-drug interactions. However, among the healthcare professionals pharmacists had good drug-drug interactions knowledge than physicians and nurses with an average score of 32.87%, 21.06% and 18.96% respectively. Drug reference books were the most cited drug-drug interaction information source used by 97 (33.10%) participants. Familiarity to the standard treatment guideline, profession and drug-drug interaction information sources were found to be associated with healthcare professionals’ knowledge of drug-drug interactions (p value