Thermodynamics of the origin of life, evolution, and aging

Thermodynamics of the origin of life, evolution, and aging

G. P. Gladyshev

Russian Academy of Arts; International Academy of Creative Endeavors; N.N. Semenov Institute of Chemical Physics, Russian Academy of Sciences, 117977 Moscow, Kosygin, 4

international Journal of Natural Science1

The main provisions of hierarchical thermodynamics created on the basis of Gibbs thermodynamics are presented. The thermodynamic theory of the origin of life, its evolution and the aging of living beings is presented. The theory considers the change in the specific Gibbs function of the formation of structures of different hierarchies, that is, the change in the comparative stability of these structures in the course of their evolutionary transformations. The described approach should be considered structural kinetic thermodynamics, which allows us not to consider any kinetic mechanisms of processes in the evolution of various hierarchical structures. It is asserted that the principle of substance stability determines the direction of the processes of the origin of life and its evolutionary transformations. The thermodynamic theory of aging and thermodynamic nutrition allows predictions concerning healthy life and its duration. It is shown that hierarchical thermodynamics is the physical foundation of expanded Darwinism. All the conclusions and predictions of the theory are confirmed by numerous observations and experimental facts.

Keywords: thermodynamics, hierarchy, origin of life, evolution, chemical evolution, aging, Darwinism, natural design.

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G. P. Gladyshev.Thermodynamics of the origin of life, evolution, and aging. International Journal of Natural Science and Reviews, 2017; 2:7.


[1]. Gibbs, J.W. (1876). The Scientific Papers of J. Willard Gibbs: “On the Equilibrium of Heterogeneous Substances”, Vol. 1, Thermodynamics, Ox Bow Press, Connecticut.
[2]. Сычев В. В. Сложные термодинамические системы. М.: Изд. дом МЭИ, 2009.
[3]. Gladyshev Georgi P., On the Thermodynamics of Biological Evolution, Journal of Theoretical Biology, Vol. 75, Issue 4, Dec 21,1978, pp. 425-441 (Preprint, Chernogolovka, Institute of Chem. Phys. Academy of Science of USSR, May, 1977, p. 46).
[4]. Gladyshev Georgi P., Thermodynamics Theory of the Evolution of Living Beings, Commack, New York: Nova Science Publishers, Inc., 1997. 142 P. In Russian: Гладышев Г.П., Термодинамическая теория эволюции живых существ, М.: ”Луч”, 1996.-86с. http://creatacad.o rg/?id=58&lng=eng
[5]. Гладышев Г.П. Супрамолекулярная термодинамика – Ключ к осознанию явления жизни. Что такое жизнь с точки зрения физико-химика. Издание второе, М – Ижевск. ISBN: 59397-21982 (2003).
[6]. Gladyshev G. P., Natural Selection and Thermodynamics of Biological Evolution, Natural Science, 7, pp. 117-126(2015). 10.4236/ns.2015.73013
[7]. Gladyshev Georgi P., Thermodynamics of Aging and Heredity, Natural Science, 7, No 5, pp. 270-286(2015). http://www.scirp. org/Journal/PaperInformation.aspx?PaperID=56613
[8]. Gladyshev G.P., The Thermodynamic Theory of Evolution and Ageing, Advances in Gerontology, 4, 109-118(2014). http://dx.doi.or g/10.1134/S2079057014020064
[9]. Гладышев Г. П. Иерархическая термодинамика и эволюция химической и биологической материи. (Gladyshev G.P., Hierarchical thermodynamics and evolution of chemical and biological matter). The scientific heritage: Budapest, Hungary. Vol. 1, № 3 (3), pp. 102-121(2016).
[10]. Gladyshev Georgi, Thermodynamics Optimizes the Physiology of Life, p. 152 – 163.
In: Philosophy & Cosmology, v. 12(2014), pp. 152-163. ISSN 2307-3705. s/2014/PhC_2014.pdf
[11]. Gladyshev G. P. On General Physical Principles of Biological Evolution, International Journal of Research Studies in Biosciences. Volume 5, Issue 3, 2017, Page No: 5-10. https://www.researchgate. net/publication/314187646_On_General_Physical_Principles_of_Biological_Evolution
[12]. Gladyshev G. P., The principle of substance stability is the driving force of evolution. substance_stability_is_the_driving_force_of_evolution
[13]. Thims Libb, Georgi Gladyshev – Thermodynamics of evolution (2010).
[14]. Bogolubov N. N. Selected works. Part 1. Dynamical Theory. – New York: Gordon and Breach Science Publishers, 1990.
[15]. Gladyshev G. P. Hierarchical Thermodynamics: Foundation of Extended Darwinism. Imperial Journal of Interdisciplinary Research (IJIR) Vol-3, Issue-2, 2017, ISSN: 2454-1362,
16. MetaCyc. Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc
17. Aging Хром кол
18. Gladyshev, G.P. (2004) Macrothermodynamics of Biological Evolution: Aging of Living Beings. International Journal of Modern Physics B, 18, 801-825.
[19]. Sang-Goo Lee at all, Age-associated molecular changes are deleterious and may modulate life span through diet. Science Advances, Vol. 3, no. 2, 17 Feb 2017
[20]. Gladyshev G.P. J Thermodyn Catal , 2017, 8: 2 DOI: 10,4172 / 2157-7544.100018,
Life – A Complex Spontaneous Process Takes Place against the Background of Non-Spontaneous Processes Initiated by the Environment
[21]. Yuri S. Lipatov, Book Review “G.P. Gladyshev, Thermodynamic Theory of the Evolution of Life Forms”, J Biol Phys . 1997 г .; 23 (2): 129-131. doi: 10.1023 / A: 1004904703383
[22]. Ершов Ю. А. Термодинамика квазиравновесий в биологических системах. Итоги науки и техники, Серия: Химическая термодинамика и равновесия, Том 5, с. 1-140. Государственный комитет по науке и технике – Академия наук СССР – Всесоюзный институт научной и технической информации. Москва, 1983, 1-8039.
[23]. Козлов Г. В., Новиков В. У. Кластерная модель аморфного состояния полимеров (рус.) // Успехи физических наук. — Т. 171, № 7. — С. 717—764.
[24]. Харитонов Ю. Я. Физическая химия, Министерство образования и науки РФ, Москва, издательская группа “ГЭОТАР – Медиа”, 2013 г. Гл. 4. Универсальные законы. Неравновесная термодинамика. Закон временных иерархий Гладышева, с. 118
[25]. Элошвили C. А. (г. Тбилиси, Грузия). О математических основах иерархической термодинамики
[26]. El-Diasty. F., (2011). Origin of Order: Emergence and Evolution of Biological Organization as a Problem in Thermal Physics. Advances in Life Sciences, 1, 30-39.
[27]. Encyclopedia Nation Master (USA):
History of thermodynamics:.
Thermodynamic evolution

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