Review Article of International Journal of Aging Research
The Genetic and environmental risk Factors of Alzheimer’s disease
Jyoti Yadav and Prof. Anoop Kumar Verma
University- King Georges Medical University, Lucknow
Alzheimer is one of the most common neurodegenerative disease generally found in the form of dementia in old age population. Advanced age is still considered as most influencing risk factors for this disease. WHO reported that dementia is the seventh leading cause of death in 2018 and affecting about fifty million people worldwide. Aging led to impair protein metabolism in the Alzheimer’s disease. A number of molecular events has been implicated behind this disease. As AD is a chronic neurodegenerative disease and etiology is still unclear, familial AD accounts only 5% of the disease. Then it is important to know about some other hidden risk factors that may play crucial role in the onset of the disease. Thus, this paper focused on the role of genetics, different environmental, oxidative stress factors and its association with the pathogenesis of Alzheimer’s disease.
Keywords: Alzheimer’s disease, Amyloid, Beta, Neurodegenerative and Oxidative stress.
How to cite this article:
Jyoti Yadav and Anoop Kumar Verma The Genetic and environmental risk Factors of Alzheimer’s disease. International Journal of Aging Research, 2018, 1:16.
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