Is Propanediol a safer molecule than some other glycols in personal care and anti-aging biocosmeceutical products?


Is Propanediol a safer molecule than some other glycols in personal care and anti-aging biocosmeceutical products?


Pierre A. Guertin

Full professor, Department of Psychiatry and Neurosciences, Faculty of Medicine, Université Laval, Quebec City, QC, Canada; Laval University Medical Center, Quebec City, QC, Canada, G1V4G2


international journal of aging research

Propanediol (1,3-propanediol) is an ingredient increasingly used by the industry for electronic cigarettes, personal care creams and anti-aging serums among many other products. For some skin care purposes, it is used to enhance the transdermal absorption of other ingredients (e.g., the actives) enabling moisturizing effects and skin smoothness to be improved. Propanediol may be derived from corn although synthetic forms also exist. It is a chemical similar to other glycols such as propylene glycol (1,2-propanediol) but generally believed to be safer. This short communication reveals in fact that only limited scientific evidence of safety is available. Preliminary signs of toxicity have been found following administration of propanediol in humans although its dose-dependent toxicity and long-term side effects on health have not been significantly explored. Consequently, as of today, skin care and anti-aging products for elderly, a vulnerable population, should not automatically be considered as safe. Those comprising 1,3-propanediol should probably be used with caution until scientifically-proven safety data for the intended purposes are obtained by independent scientists.


Keywords:glycols, 1,3- propanediol, dermatology, anti-aging, organic products, elderly, safety, toxicity


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How to cite this article:
Pierre A. Guertin. Is Propanediol a safer molecule than some other glycols in personal care and anti-aging biocosmeceutical products? International Journal of Aging Research, 2018, 1:23. DOI: 10.28933/ijoar-2018-11-1508


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