Incidence of Cognitive Decline and Association with Changes in Sociodemographic, Lifestyle, and Health Indicators in Individuals aged 50 years and older: Prospective Cohort


Incidence of Cognitive Decline and Association with Changes in Sociodemographic, Lifestyle, and Health Indicators in Individuals aged 50 years and older: Prospective Cohort


Maria Cristina Umpierrez Vieira1, 2, Douglas Fernando Dias1, Maira Sayuri Sakay Bortoletto1, Ana Maria Rigo Silva1, Marcos Aparecido Sarria Cabrera*3

1Public Health Department, State University of Londrina (UEL), Londrina (Paraná), Brazil;
2Nursing Department, State University of the Midwest of Paraná (UNICENTRO), Guarapuava (Paraná), Brazil;
3Internal Medicine Department, State University of Londrina (UEL), Londrina (Parana), Brazil


international journal of aging research

Objectives: To identify the incidence of cognitive decline (CD) in an urban community-dwelling population aged 50 years and older in a 4-year follow-up period and its prospective association with sociodemographic factors, lifestyle and health conditions as well as with changes in these factors.

Methods: This is a prospective cohort with a representative sample of people aged 50 years and older (n = 206) from Cambé, PR, where baseline data collection occurred in the year 2011 and the follow-up occurred in 2015. The incidence of CD was the outcome of this study, and its evaluation occurred through the Mini-Mental State Examination.

Results: The incidence of CD was 13.1% over the 4 years of follow-up, and adjusted Poisson regression models (sex, age and age range) showed that this condition was prospectively associated with depression (adjusted relative risk (RR) = 3, 50, 95% CI = 1.65-7.43). When analyzing the effect of sociodemographic factor changes on CD, it was verified that the risk of CD was 2.86 times higher among the group that stopped having a companion in the 4 years of follow-up when compared to the group that maintained a companion in that same period, independent of confounding factors.

Conclusion: The data suggest that the CD process begins before the age of 60 y and that aggravation is associated with potentially modifiable factors that can be approached by health services from the perspective of promotion, prevention and care.


Keywords: Cognition. Middle age. Mental health. Cohort.


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How to cite this article:
Maria Cristina Umpierrez Vieira, , Douglas Fernando Dias, Maira Sayuri Sakay Bortoletto, Ana Maria Rigo Silva, Marcos Aparecido Sarria Cabrera. Incidence of Cognitive Decline and Association with Changes in Sociodemographic, Lifestyle, and Health Indicators in Individuals aged 50 years and older: Prospective Cohort . International Journal of Aging Research, 2019, 2:39. DOI: 10.28933/ijoar-2019-06-2105


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