MILK BIOFORTIFICATION MAY PROMOTE HEALTH BENEFITS IN INSTITUTIONALIZED OLDER PEOPLE

MILK BIOFORTIFICATION MAY PROMOTE HEALTH BENEFITS IN INSTITUTIONALIZED OLDER PEOPLE

Karina Pfrimer¹*, Eduardo Ferriolli¹, Márcia Saladini Vieira Salles², Luiz Carlos Roma Junior², Marcus Antônio Zanetti³, Cesar Gonçalves Lima³, Rutinéia de Fátima Micheletto¹, Daniela Takaara¹, Julia Keiko Sakamoto Hotta¹, Vivian Marques Miguel Suen¹, Fernanda Aparecida Domenici¹, Helena Teixeira Godoy⁴, Adriana Dillenburg Meinhart⁴, Arlindo Saran-Netto³, Helio Vannucchi¹

¹Department of Internal Medicine, Medical School of Ribeirão Preto – University of São Paulo, Ribeirão Preto, Brazil, ²Animal Science Institute, Secretary of Agriculture and Supply of the State of São Paulo, Ribeirão Preto, Brasil, ³College of Animal Science and Food Engineering, University of São Paulo, USP, Brazil,⁴Departament of Food Science, Food Engineering School, Campinas State Univ. (UNICAMP), Campinas, Brazil.

The aim of this study was to measure the changes caused by biofortified milk enriched with selenium, vitamin E and/or improved fatty acid profile in biochemical parameters of institutionalized older people. 132 institutionalized older persons were divided into four groups who received the following treatments: C= Control milk with 3.98 µmol/l vitamin E, 0.37 µmol/l selenium, 2.24 mmol/l CLA; A= Biofortified milk with 5.05 µmol/l vitamin E, 3.63 µmol/l selenium, 6.57 mmol/l CLA; O= Biofortified milk with 4.28 µmol/l vitamin E, 0.20 µmol/l selenium, 5.71 mmol/l CLA and AO=5.21 µmol/l vitamin E, 4.42 µmol/l selenium, 6.85 mmol/l CLA for 12 weeks. Consumption of AO or O milk decreased total cholesterol in 6.8 % (p=0.0429) and LDL in 10.6 % (p=0.0292). Participants who consumed O milk had a higher HDL (42.6±1.2 mg/dl) than those who consumed A (37.7±1.2 mg/dl, p=0.0047). The consumption of biofortified milk with selenium, vitamin E and CLA, resulted in a better lipid profile and higher plasma antioxidant levels in institutionalized elderly.

Keywords: aging, nutrients, milk, dietary biofortication

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Karina Pfrimer, Eduardo Ferriolli, Márcia Saladini Vieira Salles, Luiz Carlos Roma Junior, Marcus Antônio Zanetti, Cesar Gonçalves Lima, Rutinéia de Fátima Micheletto, Daniela Takaara, Julia Keiko Sakamoto Hotta, Vivian Marques Miguel Suen, Fernanda Aparecida Domenici, Helena Teixeira Godoy, Adriana Dillenburg Meinhart, Arlindo Saran-Netto, Helio Vannucchi. Milk biofortification may promote health benefits in institutionalized older people. International Journal of Aging Research, 2022, 5:98. DOI: 10.28933/ijoar-2022-04-1205kp

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