Review Article of International Journal of Stem Cell Research
Effiong Edet Bassey
Dept. of Applied Microbiology and Brewing Nnamdi Azikiwe University, Awka Nigeria
Lymphoma is the general term for cancers that develop in the lymphatic system. Lymphoma originates in developing lymphocytes (B-cells and T-cells), which have undergone a malignant change. They multiply without any proper order, forming tumours, which are collections of cancer cells. These tumours cause swelling in the lymph nodes and other parts of the body. Over time, malignant lymphocytes (called lymphoma cells) crowd out normal lymphocytes and eventually the immune system becomes weakened and can no longer function properly.
This lymphoma affects the lymph nodes first, and could also affect other lymphoid organs like spleen and bone marrow.
The Non-Hodgkins lymphoma can be classified into 2, depending on how fast or slow these tumors grow within the body namely; Aggressive non-hodgkins lymphoma and Indolent non¬ hodgkins lymphoma.
Non-hodgkins lymphoma can also be classified based on the type of cells they emanate from namely; B-cells lymphoma and T-cells lymphoma. B-cell lymphoma are lymphomas that arise from developing B-cells, while T-cell lymphoma are lymphomas that arise from T -cells. The causes of non-hodgkins lymphoma includes infection like the Epstein-Barr virus infection in patients from specific geographic regions, exposure to certain chemicals ingredients in herbicides and pesticides such as organochlorine and phenoxy acid can lead to lymphoma and also immunosuppression. The extent to which the lymphoma has spread in body is called the stage of the disease. In stages 1 and 2, lymphoma is limited to one or two areas of the body (early stage). In stages 3 and 4, the disease is more widespread in the body (advanced stage). It’s signs and symptoms includes; enlarged lymph node in the neck, fever, excessive sweating, unexplained fatigue, loss of appetite or weight loss. Non-hodgkins lymphoma are usually diagnosed by examining a lymph node biopsy specimen under a microscope using either core biopsy or surgical biopsy. Non-hodgkins lymphoma can be treated using chemotherapy and radiation therapy as the two principal forms of treatment for NHL’. Stem cell transplantation can also be used for treating Non-Hodgkins lymphoma. A healthy and nutritious diet is important to help your body cope with your disease and treatment.
Keywords: Non-hodgkings Lymphoma
How to cite this article:
Effiong Edet Bassey. Non-hodgkings Lymphoma. International Journal of Stem Cell Research. 2018, 1:3
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