Hepatitis B Surface Antigen (Obsag) In Pregnant Women Attending Antenatal Clinic At The General Hospital, Amaku, Awka, Anambra State, Nigeria

Hepatitis B Surface Antigen (Obsag) In Pregnant Women Attending Antenatal Clinic At The General Hospital, Amaku, Awka, Anambra State, Nigeria

Effiong Edet Bassey, Ebere I. Okoye

Department of Applied Microbiology and Brewing, Nnamdi Azikiwe University, Awka, Nigeria

International Journal of stem cell research

This study was carried out to determine the prevalence of HBsAg among pregnant women attending antenatal clinic at General Hospital in Agba, Ekwulobia, Anambra State. Two hundred pregnant women who consented voluntarily after thorough explanation of the purpose of the study were recruited for this study. The samples were tested for the presence of antibodies using rapid Dia Spot HBsAg rapid test strip developed by Dia Spot Diagnostics, USA and ClinotechHBsAg (Clinotech diagnostics, Richmond, Canada). Analysis of the result showed that 23 (11.5%) of the pregnant women had HBsAg. Statistical analysis, however, showed no significant difference between the prevalence and the age of patients, parity, trimester and type of family. The frequency of HBY carriers did not vary significantly with the Use of condoms and contraceptives. However, there was a significant frequency variation in the distribution of HBsAg between those that have previous history of transfusion, operation, circumcision and those who never had history of operation, transfusion or circumcision Therefore, the need to institute public health measures to reduce disease burden and transmission, including routine screening of all pregnant mothers for HBV infection and early passive-active immunization of babies born to HBsAg-positive mothers are advocated.

Keywords: Cellularity, Umbilical Cord, Stem Cells, Placenta, Blood, Transplant

Free Full-text PDF

How to cite this article:
Effiong Edet Bassey, Ebere I. Okoye. Hepatitis B Surface Antigen (Obsag) In Pregnant Women Attending Antenatal Clinic At The General Hospital, Amaku, Awka, Anambra State, Nigeria. International Journal of Stem Cell Research. 2018, 1:4


1. Adhool and Karim (1991). Transmission of serum hepatisis. The New England Journal of Medicine, 285 (4): 185-189.
2. Awole, M. and Gebre-Selassie, S. (2005), Seroprevalence of HbsAg and its risk factors among pregnant women in Jimma, Southwest Ethiopia. Ethiopia Journal of Health Development, 19 (1): 45-50.
3. Dao, B., Nacro, B., Dahourou, H. (2001). HIV infection and HBV co-infection: survey of prevalence in pregnant women in Burkina Faso. Revenue Medicale de Bruxelles, 2: 83-86.
4. Deinstag, D.L., Hollinger, M. and Stephen, M.D. (1995) Epidemiology of Hepatitis B in Europe and Worldwide. Transfuse Medical 10: 185-180.
5. Dienstag, J.L. (1981). “Hepatitis B as an immune complex disease”. Seminars in Liver Diseases, 1 (1): 45-57.
6. Engy, Yousry and Elsayed, Ashor (2011). Overview on Heptitis B virus. Nature and Science, 9 (3): 31-36.
7. Ezegbudo, C.N., Agbonlahor, D.E., Nwobu, G.O., Igwe, C.U., Agba, M.I., Okpala, H.O., Ikaraoha, C.I. (2004). Theseroprevalence of hepatitis B surface antigen and human immunodeficiency virus among pregnant women in Anambra State, Nigeria. Department of Internal Medicine Shiraz E-Medical Journal, 5 (2): 1-8 16.
8. Holling, D.M., Gogos, A.C. and Fouka, K.P. (1995) Prevalence of Hepatitis B and C Viral Infections in the General Population and Selected groups in South Western Greece. Journal of Infectious Diseases; 18: 551-557.
9. Lindsley, T.K., Skoutelis, A. and Bassaris, H. (1990), Control of Hepatitis B Virus Infection in Third World Countries. Journal of Transfies Medical Review, 43 (3): 187-190.
10. Ryan, S. and Ray, M. (2004). Atlas of Clinical Haematology, 60: 326-327.
11. Savel, A.M. and Andelman, B. (2005). Strategy for the Control of Hepatitis B Viral Infection in the Middle East and North Africa. Vaccine 8: 5117-5128.
12. Seeger, C., Knipe, D.M., Howley, P., Zoulim, f., Mason, W.F. (2007). Hepadnaviruses. In Field Virology, 5th Edition, (eds.), 60 : 2978-3029.
13. Seeger, B. and Mason, A.M. (2000). Viral Hepatitis In “Marents and molimand, A.A.F. (eds), Tropical Geographical Medicines. Pp 572-576.
14. Stevens, C.E., Taylor, P.E., Pindyck, J. (1990). Epidemiology of hepatitis C virus: a preliminary study of volunteer blood donors. Journal of the American Medical Association; 263: 49-53.
15. Stewart, F.S and Beswick, T. (2005). External Lamivudine Retreatment for Chronic Hepatitis B: maintenance of viral Suppression after Discontinuation of Therapy. Hepatology, 30: 1082-1087.
16. Thio, C.L., Seaberg, E.C., Skolasky, R. (2002); HBV and the risk for liver-related mortality in the multicenter cohort study. Lancet, 360: 1921-1926.
17. Zukerman, A.J (1996), “Hepatitis Viruses”. In Baron S, et al. Baron’s Medical Microbiology (4th edition). University of Texas Medical Branch, 45 (3): 982-985

Terms of Use/Privacy Policy/ Disclaimer/ Other Policies:
You agree that by using our site, you have read, understood, and agreed to be bound by all of our terms of use/privacy policy/ disclaimer/ other policies (click here for details).

This work and its PDF file(s) are licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.