A traditional formulation of Shorea robusta resin found effective in excision wound model in rats

A traditional formulation of Shorea robusta resin found effective in excision wound model in rats

Shrijana Shakya and Deepak Bashyal

Department of Pharmacy, Institute of Medicine

International Journal of Traditional and Complementary Medicine

A large proportion of the population of developing countries still uses traditional medicines, either as a result of the high cost of Western pharmaceuticals and health care, or because the traditional medicines are more acceptable from a cultural and spiritual perspective(1). The WHO estimates nearly 80% of the population still depends upon herbal medicines due to their easy availability, low cost and possible less side effects as compared to allopathic system of medicines(2). These also cover healthcare systems that include beliefs and practices relating to diseases and health, which are products of indigenous cultural development and are not explicitly derived from a conceptual framework of modern medicine. Ingredients used in the preparation of those remedies may even provide attractive templates for the development of new pharmaceutical products(3).
All the people of Nepal have no access to allopathic medicine and health center because of illiteracy, poverty and unavailability. Thus, about 80% of the population in Nepal relies on traditional medicine(4). One such example is the use of formulation containing Shorea robusta resin, prepared by local practitioners themselves, for treating infected wounds and burns by some locals in Kathmandu valley. The ingredients used in traditional medicine, therefore, must be recognized and studied, not only as therapeutic agents with verifiable pharmacodynamic properties, but as agents of healing with beneficial effects, even when the precise mode of activity has not been properly understood(3).

Keywords: Antifungal evaluation, Plant extracts, Phytochemicals, Nigerian medicinal plants, Botanical description, Constituuents,Euphorbia hirta, Ficus asperifolia, Momordica charantia, Nicotiana tabacum and Spondias mombin .

Free Full-text PDF

How to cite this article:
Shrijana Shakya and Deepak Bashyal. A traditional formulation of Shorea robusta resin found effective in excision wound model in rats.International Journal of Traditional and Complementary Medicine 2018, 3:12. DOI: 10.28933/ijtcm-2018-10-0401


1. Cunningham AB. An investigation of the herbal medicine trade in Natal/KwaZulu. Investigational Report No 29 Institute of Natural Resources 1988.
2. Sandhya S, Sai KP, Vinod KR, Banji D, Kumar K. Plants as potent antidiabetic and wound healing agents- A Review. Hygeia- Journal of Drugs and Medicines. 2011;3:11-9.
3. Iwu M. Introduction: therapeutic agents from ethnomedicine Ethnomedicine and Drug Discovery. 2002.
4. Manandhar NP. Plants and People of Nepal. Oregon, Timber Press. 2002.
5. Merish S, Tamizhamuthu M, Walter TM. Review of Shorea robusta with special reference to traditional Siddha Medicine. Research and Reviews: Journal of Pharmacognosy and Phytochemistry. 2014;2(1).
6. Kumar MS, Sripriya R, Raghavan HV, Sehgal P. Wound healing potential of Cassia fistula on Infected Albino Rat Model. Journal of Surgical Res 2006;131:283-9.
7. Strodtbeck F. Physiology of wound healing. Newborn Infant Nursing Reviews. 2001;1(43-51).
8. Bowler PG, Duerden BI, Aemstrong DI. Wound Microbiology and associated approaches to wound management. Clinical Microbiologucal Reviews. 2001;14:244-69.
9. Krishnan P. The Scientific Study of Herbal Wound HEaling Therapies: Current State of Play. Curr Anaes Crit Care. 2006;17:21-7.
10. Taranalli AD, Kuppast IJ. Study of Wound Healing Activity of Trigonella foenumgraceum in Rats. International Journal of Pharmaceutical Science. 1996;58(3):117-9.
11. Udupa AI, Kulkumi DR, Udupa SI. Effects of Tridax procumbens Extracts on Wound Healing International Journal of Pharmacognosy. 1995;33(1):37-40.
12. Kakali Saha PKM, J. Das, M. Pal, B.P. Saha. Wound healing activity of Leucas lavandulaefolia Rees Journal of Ethnopharmacology. 1997;56:139-44.
13. Clark RAF. Cutaneous wound repairs. In: Goldsmith LA (ed.). Physiology, Biochemistry and molecular biology New York Oxford University Press. 1991:576.
14. Rupesh Thakur NJ, Raghvendra Pathak, and Sardul Singh Sandhu. Practices inWound Healing Studies of Plants Evidence-Based Complementary and Alternative Medicine 2011:17.
15. Bhat RS, Shankrapaa J, Shivakumar HG. Formulation and Evaluation of Polyherbal Wound Treatments. Asian Journal of Pharmaceutical Sciences. 2007;2(1):11-7.
16. T A Wani HHC, D Kumar, R Prasad, A Gopal, K K Sardar, S K Tandan Wound healing activity of ethanolic extract of Shorea robusta Gaerte.f resin. Indian Journal of Experimental Biology. April 2012(a);50:277-81.
17. Mohammad Yaseen Khan SAA, and Kilambi Pundarikakshudu. Wound healing activity of extracts derived from Shorea robusta resin Pharmaceutical biology.
18. Hema Sharma Datta SKM, and Bhushan Patwardhan. Wound Healing Activity of Topical Application Forms Based on Ayurveda Evidence-Based Complementary and Alternative Medicine 2011:10.
19. Wani TA ea. Analgesic activity of the ethanolic extract of Shorea robusta resin in experimental animals. . Indian J Pharmacol 2012;44:493-9.

Terms of Use/Privacy Policy/ Disclaimer/ Other Policies:
You agree that by using our site, you have read, understood, and agreed to be bound by all of our terms of use/privacy policy/ disclaimer/ other policies (click here for details).

This work and its PDF file(s) are licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.