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International Journal of Food and Nutrition Research

International Journal of Food and Nutrition Research, Recent Articles

The role of PGC-1α in mitochondrial transcription factors: A promising pathway in the treatments of mitochondrial diseases activated by Gynostemma pentaphyllum

Review Article of International Journal of Food and Nutrition Research The role of PGC-1α in mitochondrial transcription factors: A promising pathway in the treatments of mitochondrial diseases activated by Gynostemma pentaphyllum Ferro M., Channan G. FG Scientifica and Science Department at Nutrition Formulators Inc., Miramar, Fl, 3260 Executive way, Parkway, Miramar, Fl 33025 Miramar, Fl, USA. The peroxisome proliferator-activated receptor-gamma coactivator 1α (PGC-1α), being a key transcription factor in mitochondrial biogenesis, interacts as a coactivator of several mitochondrial nuclear transcription factors, such as nuclear respiratory factor (NRF) 1 and 2, estrogen-related receptor α (ERRα), as well as non-nuclear receptor myocyte-enhancing factor 2 (MEF-2). Gynostemma pentaphyllum (GP) is a plant used in many countries, mainly in Asia, having strong activity in PGC-1α. A wide range of GP pharmacological properties has been reported, including anti-inflammatory and antioxidant activity, lipid metabolism modulator, and neuroprotective activity. The activation of PGC-1α by exogenous factors has become a promising strategy in the treatment of various pathologies, especially when focused on mitochondria. In our review, we found numerous benefits of GP in controlling age-associated metabolic diseases, mainly in diabetes type 2, fat liver, and obesity. Some studies have also reported that, due to the strong phosphorylation of AMP protein kinase (AMPK) exerted by GP, GP-treated mice showed a significant increase in Sirtuin 1 (SIRT1) mRNA expression, a protein that acts directly on cellular aging processes. However, further studies in humans could provide more proof of its efficiency in diseases such as metabolic syndrome as well as any other pathology that involves changes in mitochondrial functions. Keywords: Gynostemma pentaphyllum, PCG-1α, mitochondria, AMPK, SIRT1, metabolic syndrome ...
International Journal of Food and Nutrition Research, Recent Articles

Drought tolerant and Early-maturing Sorghum Technologies Demonstration for Food and Feed security

Research Article of International Journal of Food and Nutrition Research Drought tolerant and Early-maturing Sorghum Technologies Demonstration for Food and Feed security in the selected AGP-II districts of Harari region and Dire Dawa Administration Abdulaziz Teha1 *, Ibsa Aliyi1, Bedasso Urgessa1, Oromiya Magersa1, Jemal Yousuf2  1Oromia Agricultural Research Institute, Fadis Agricultural Research Centre; 2Haramaya University, Department of Rural Development and Agricultural Extension Food for human and feed insecurity livestock is integrated systems that have been foe small holder farmers in Ethiopia in general and study area in particular. To reduce this problem this research was conducted with objectives of promoting and popularize improved lowland sorghum technologies and to create awareness through giving training and enhance stakeholders participation. A total of fifteen (20) trial farmers were selected from two potential sorghum growing kebeles of Dire Dawa administration and one from Harari region rural areas. Four FRG having 60 farmers was established. Two improved sorghum varieties (Melkam and Dekaba) were replicated on the plot of 20mx20m. Training on which a total of 78 participants took part were organized at research sites. Lowland Sorghum varieties were evaluated based on their early maturity, yield, Disease tolerance, seed color, seed size, biomass, and stalk and food test. The yield performance of the improved varieties (Melkam and Dekeba) were 26.58 and 26.44 qt/ha at Dodota, 28.24 and 26.78 qt/ha at Bishan Bahe respectively. The average yield performance of Melkam somewhat higher than Dekaba at both location but statistically no significant difference between two improved varieties across the locations and the biomass/stalk was high which helps for livestock feed. Thus, Melkam variety preferred well for these benefits over dekeba. Therefore, it is recommended that government, nongovernment and other stakeholders should popularize to reach large small holder farmers in similar agro-ecology. Keywords: Sorghum, Demonstration, Drought, Early-maturing, Melkam and ...
International Journal of Food and Nutrition Research, Recent Articles

Nutritional condition, dietary and activity patterns of Primary School Childrens

Research Article of International Journal of Food and Nutrition Research Nutritional condition, dietary and activity patterns of Primary School Childrens in Eravurpattu Division S.Lakshan, Neel Chandrasekara Department of Agriculture, Kandy, Sri Lanka Normally the level of nutrition status of School children in Sri Lanka is not favorable. The Situation is worst in the areas affected by ethnic conflict. Main objectives of this research were studying the current nutritional conditions and contributory factors that have been forced for this situation and remedial measures which could be adopted to correct the situation then we selected primary schools Childrens are from five schools in affected areas. They are Karadiyanaru Maha Vidthiyalayam, Ellupattichenai ambal Vidthiyalayam, Pankudavale Roman Catholic Vidthiyalayam, Kiththul Srikrishna Vidthiyalayam, Pullumalai Roman Catholic Vidthiyalayam. Were selected for this study and multi stage sampling method was used. Samples were randomly selected for areas and Data’s were collected in the form of interview schedule and dietary survey questionnaires. To find out the relationship between contributory factors and nutritional conditions, regression analysis method was used. Survey findings reported that there was a positive relationship between nutrition conditions and food consumption, income, and good sanitation practices. There was a negative relationship between nutritional conditions, infections diseases and body mass index among the dependents of the family. In case of food consumption (Calorie intake) and infectious diseases, there was a negative relationships between these two factors. Further considering the matter of age limits some differences were observed between standard weight and the normal weights of the targeted group. Having compared with standard values, it was found that 38% of school children were stunted, 42.24% were under weight. 20% were wasted there for it can be concluded that the nutritional status of school children in the selected school is poor. Thus immediate attention should be paid to correct ...
International Journal of Food and Nutrition Research, Recent Articles

Physicochemical and Rheological Properties of Ethiopian Honey

Research Article of International Journal of Food and Nutrition Research Physicochemical and Rheological Properties of Ethiopian Honey Teferi Damto Holeta Bee Research Center, Oromia Agriculture Research Institute Ethiopia has about 10 million bee colonies, the largest bee population in Africa and the largest honey producer in Africa, and the tenth-largest honey producer all over the world. The total honey production of Ethiopia is estimated to be 53 000 tons. Honey is a viscous, aromatic, sweet food that is consumed and enjoyed by people around the world. For this reason, it requires certain standards and norms that guarantee its identity and quality so that consumers may safely consume honey, and the same shall have free circulation in the internal market and access to the external market. Honey quality is determined by its physicochemical and rheological constituents. Knowing honey characteristics is useful for processing, packaging, and storage of honey in appropriate conditions which are used to preserve their qualities and know their nutritional and medicinal value as well. The majority of Ethiopian honey possesses good characteristics in terms of physicochemical and rheological properties although there is a slight variation among parameters due to different factors. Training and creating awareness beekeepers and other stakeholders on honey quality may reduce the problem related to honey quality. Keywords: Physicochemical; Rheological; Quality; Honey; Ethiopian ...

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International journal of food and nutrition research

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