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International Journal of Hospital Pharmacy

International Journal of Hospital Pharmacy

Healthcare professionals’ awareness towards drug-drug interaction in Ayder comprehensive specialized hospital Mekelle, Ethiopia

Research Article of International Journal of Hospital Pharmacy Healthcare professionals’ awareness towards drug-drug interaction in Ayder comprehensive specialized hospital Mekelle, Ethiopia Betelhem Endal1, Desalegn Getnet2, Desye Gebrie1 1.Pharmacoepidemiology and Social Pharmacy Course and Research Team, School of Pharmacy, College of Health Science, Mekelle University, Mekelle, Ethiopia; 2.Pharmacology and Toxicology Course and Research Team, Department of Pharmacy, Adigrat University, Adigrat, Ethiopia Background: Healthcare professionals are the most responsible body to identify potential interaction of drugs that are prescribed as well as those that the patient may be self-administering. However, awareness of healthcare professionals towards drug-drug interaction is poor. So to improve patient medication safety, it is important to assess healthcare professionals’ knowledge pertaining to drug-drug interactions and common drug-drug interactions information sources. Method: Cross-sectional study design was employed. Self-administered questionnaire was prepared to assess healthcare professionals’ knowledge of drug-drug interactions and usual sources of drug-drug interaction information. Participants were asked to classify 10 drug pairs as ‘contraindicated’, ‘can be used with monitoring’, ‘no interaction’ and ‘not sure’. Study was conducted from November 2017 to June 2018. Participants were selected using simple random sampling method. Data were analyzed using statistical software, SPSS for windows version 20. The relationship between knowledge and independent variables (age, sex, profession, work experience, training, familiarity with standard treatment guideline perception and source of information) was assessed using binary logistic regression analysis (Crude and adjusted Odds ratio, 95% confidence interval). Result: The study was done by enrolling 293 healthcare professionals among whom 46 were Physician, 31 Pharmacist, and 216 Nurses. Over all, healthcare professionals in Ayder Comprehensive Specialized Hospital had low score (24.29%) knowledge of drug-drug interactions. However, among the healthcare professionals pharmacists had good drug-drug interactions knowledge than physicians and nurses with an average score of 32.87%, 21.06% and 18.96% respectively. Drug reference books were the most ...
International Journal of Hospital Pharmacy

An observation cross sectional study to assess the prevalence of micro vascular complications in diabetes

Research Article of International Journal of Hospital Pharmacy An observation cross sectional study to assess the prevalence of micro vascular complications in diabetes Nishad Unissa, Mariya Mahveen, Shiva Kumar, Katla. Swapna Department of Pharma.D, Bharat Institute of Technology-Pharmacy, Mangalpally, Ibrahimpatnam, KIMS, Telangana 501510, India. Diabetes mellitus is the commonest metabolic disorder and has a high prevalence in India. The prognosis of the diabetic patients largely depends on the complications seen in the natural course of illness. It was decided to undertake observational study to record various complications and the influence of various risk factors.(1) Diabetes mellitus is a long term metabolic disorder that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.(2) Diabetes is a syndrome characterised by chronic hyperglycemia and disturbance of carbohydrate, fat and protein metabolism associated with absolute or relative deficiencies in insulin secretion and/or insulin action(3). Complications of diabetes The longer duration of diabetes the less controlled of blood sugar levels leads to development of diabetic complications which are divided into microvascular ( damage to small blood vessel) and macrovascular (damage to large blood veseels). • Micro vascular complications: These are Long term complications that affect retina, kidney and nervous system(3). Permanent disability is a common outcome of diabetes, with late complications of diabetes being major determinants for disability. Diabetic eye disease particularly retinopathy, has become a major cause of blindness throughout the world. • Macro vascular complications: Type 2 diabetes can also affect the large blood vessels, causing plaque to eventually build up and potentially leading to a heart attack, stroke or vessel blockage in the legs (peripheral vascular disease) Diabetic foot also occur with higher frequency in diabetes(4,5). Keywords: cross sectional study, prevalence of microvascular complications, diabetes ...
International Journal of Hospital Pharmacy

Case Study of Gabapentin Induced Exfoliate Dermatitis

Research Article of International Journal of Hospital Pharmacy Case Study of Gabapentin Induced Exfoliate Dermatitis Katla Swapna, Mounika, Nishad Unissa Department of Pharma. D, Bharat Institute of Technology-Pharmacy, Mangalpally, Ibrahimpatnam, KIMS, Telangana 501510, India. OBJECTIVE : To report a case of possible Gabapentin-induced Exfoliate Dermatitis CASE SUMMARY : A 62 old male patient with the chief complaints of rash since 10 days . He was on treatment with Gabapentin and Pregabalin for paraesthesias by neurosurgeon from last month. Developed rash all over the body since 10 days. Past history includes similar rashes due to Diclofenac. No history of Psoriasis/eczema/no history of weight loss/cough/blood in stools. On examination patient has generalised scaling over background of erythema all over the body, exfoliation with rise of temperature. This presentation is consistent with the features of Exfoliative Dermatitis. Resolution of the clinical manifestations was observed after discontinuation of the drug; all other drugs, infections, or immunologic disorders that could have caused this syndrome were carefully excluded. An objective causality assessment revealed that exfoliative dermatitis was possibly associated with the use of Gabapentin. CONCLUSIONS: Although Gabapentin administration seems to be the underlying cause of the Exfoliative Dermatitis observed in our patient, establishment of a definite causal relationship requires additional cases and supportive data. Keywords: Exfoliative dermatitis, Erythema multiforme ...
Open Access, International Journal of Hospital Pharmacy, Most Read

Prevalence of Plasmodium Falciparum Malaria and the Antenatal Health Care Utilization for Prevention Among Pregnant Women in a Secondary Health Facility in Enugu State, Nigeria

Research Article of International Journal of Hospital Pharmacy Prevalence of Plasmodium Falciparum Malaria and the Antenatal Health Care Utilization for Prevention Among Pregnant Women in a Secondary Health Facility in Enugu State, Nigeria Maureen Ogochukwu Akunne*, Ebere Emilia Ayogu, Juliana Obianuju Idoko. Department of Clinical Pharmacy and Pharmacy Management, Faculty of Pharmaceutical Sciences, University of Nigeria, 410001 Nsukka, Enugu State, Nigeria Pregnant women in endemic areas are highly susceptible to malaria, and both the frequency and severity of the disease are higher in pregnant women than non- pregnant women.[1] In pregnancy, there is a transient depression of cell mediated immunity that allows foetal allograft retention but also interferes with resistance to various infectious diseases. Malaria infection during pregnancy is a major public health problem in the tropics and subtropics. It affects approximately 24 million pregnant women.[2] In the area of Africa with stable malaria transmission, plasmodium falciparum infection during pregnancy is estimated to cause as many as 10,000 maternal death each year, 8-14% of all low birth weight babies and 75,000-200,000 of all infant death.[3] In Nigeria, there is an estimated 25-30% of mortality in children under the age of five and 300,000 death each year due to malaria.[3] Studies have shown that 40% of pregnant African women start attending antenatal clinics in the first and second trimester of their pregnancy. [3] In addition, pregnant women are at immense risk of malaria due to natural immune depression in pregnancy. [4] The symptoms and complications of malaria during pregnancy differ with the intensity of malaria transmission and thus with the level of immunity the pregnant woman acquired. [5] Malaria cases and death have been increasing in the country mainly due to injudicious use of anti-malaria drugs, delayed health seeking and reliance on clinical judgment without laboratory confirmation in most of the ...


Editor-in-chief: 
Dr. Fadi Alkhateeb 
Associate Dean of Academic Affairs and Associate Professor, Ben and Maytee Fisch College of Pharmacy, The University of Texas at Tyler, 3900 University Blvd, Office # 328, Tyler, TX 75799

Vice Editor-in-Chief:
Dr. Saurabh Gupta 
Professor and Head, Department of Pharmacology, Indore Institute of Pharmacy, Indore (M.P.), India; Principal Co-ordinator Scientist for outsources projects of industry, Indore institute of Pharmacy, Indore (M.P.), India,; Scientist Co-ordinator member of Institutional Animal Ethical Committee, Indore institute of Pharmacy, Indore.

Editors

Dr. Mohammed A. Islam
Department of Pharmaceutical Sciences, West Coast University School of Pharmacy, Los Angeles, CA, USA.

Dr. Juseop Kang
Department of Pharmacology and Clinical Pharmacology Laboratory, College of Medicine, Hanyang University, Seoul 133-791, South Korea.

Dr. Mohamed Azmi Hassali
Professor of Social and Administrative Pharmacy, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang, Malaysia.

Dr. Quanxi Mei 

Guangzhou University of Chinese Medicine,  Zhongshan,Guangdong, China.

Dr. Apollo James
Department of Pharmacy Practice, Nandha college of Pharmacy, Erode, Tamilnadu, India.

Dr. Iftikhar Ali
Department of Pharmacy, Northwest General Hospital and Research Center, Department of Pharmacy, University of Swabi, Khyber Pakhtunkhwa , Pakistan.

Dr Anthony David Hall
School of Clinical Sciences, Queensland University of Technology (QUT), Brisbane, Australia.

Dr Bhanukumar M
Department of General Medicine, JSS Hospital & Medical College, JSS University, Mysore, India.

Dr. Sandeep Kumar Kar
Institute of Postgraduate Medical Education & Research, India.

Dr. Biswaranjan Paital
Department of Zoology, Orissa University of Agriculture and Technology, College of Basic Science and Humanities, Bhubaneswar-751003, Odisha, India.

Dr. Vasiliki E. Kalodimou
Director at Flow Cytometry-Research & Regenerative Medicine Department, Athens, Greece.

Dr. Hale Z. Toklu
Department of Pharmacology & Therapeutics, University of Florida College of Medicine, 32610 Gainesville, FL, USA.

Dr. Fahad Saleem
Discipline of Social and Administrative Pharmacy, School of Pharmaceutical Sciences, Universiti Sains, Malaysia, Minden 11800, Penang, Malaysia

Dr. Ahamada Safna Mariyam.M
Dept of Pharmacy Practice, Acharya & B.M Reddy College of Pharmacy, Bangalore-107, India.

Dr. Ghada Ismail El Shahat Ali Attia
Literature of Pharmacognosy, Departments of Pharmacognosy, Faculty of Pharmacy, TANTA University- Egypt

Dr. Tauqeer Hussain Mallhi
School Of Pharmaceutical Sciences, Usm, Penang, Malaysia

Dr. Burton M. Altura

Physiology and Pharmacology Department， SUNY Downstate Medical Center， NY, USA.

Dr.  Yousif Abdu Asiri
Vice – Rector for Planning and Development, Professor of Clinical Pharmacy， King Saud University,， Riyadh 11451, Saudi Arabia.

Dr. Amit K. Tiwari
Department of Pharmacology & Experimental Therapeutics， The University of Toledo – Health Science Campus， Toledo, OH, USA.

Dr. Saurabh Gupta
Professor and Head, Department of Pharmacology, Indore Institute of Pharmacy, Indore (M.P.), India, Principal Co-ordinator Scientist for outsources projects of industry, Indore institute of Pharmacy, Indore (M.P.), India, Scientist Co-ordinator member of Institutional Animal Ethical Committee, Indore institute of Pharmacy, Indore.

Dr. Tyler Madere
University of North Texas System College of Pharmacy –Department of Pharmacotherapy, Fort Worth, TX，USA.

Dr. Xianquan Zhan
Professor and Deputy Director, Xiangya Hospital, Central South University, Changsha, Hunan, P.R. China

Dr. Fatima Suleman
Head of Discipline of Pharmaceutical Sciences, School of Health Sciences, College of Health Sciences of University of KwaZulu-Natal, Durban, South Africa.

Dr. Mohamed Eddouks
Faculty of Sciences and Techniques Errachidia, Moulay Ismail University, Meknes, Morocco.

Dr.  Syed A. A. Rizvi 
Department of Pharmaceutical Sciences, College of Pharmacy, Health Professions Division, Nova Southeastern University, FL, USA.

Dr. Carmela Saturnino 
Faculty of Pharmacy, University of Salerno, SA, ITALY.

Dr. Taha Nazir
University of Sargodha, Sargodha 40100, Pakistan.

Dr. Fadi Alkhateeb
Pharmacy Administration, Department of Pharmacy Practice, Irma Lerma Rangel College of Pharmacy, Texas A&M Health Science Center, Kingsville, Texas, USA.

Dr. Madhan Ramesh
Professor & Head, Department of Pharmacy Practice, JSS College of Pharmacy, JSS University, S S Nagar, Mysore.

Sushanta Kr. Das.
M. Pharm (Pharmacy Practice), Associate Professor and Pharm D Coordinator, CMR College of Pharmacy, Hyderabad

Dr. Mario Bernardo-Filho
Professor Titular, Universidade do Estado do Rio de Janeiro

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References: References should be listed in a numbered citation order at the end of the manuscript. DOIs and links to referenced articles should be added if available. Abstracts and talks for conferences or papers not yet accepted should not be cited. Examples Published Papers: 

1.Kim P.G.M. Hurkens, Carlota Mestres-Gonzalvo, Hugo A.J.M. de Wit, Rob Janknegt, Frans Verhey, Jos M.G.A. Schols, Fabienne Magdelijns, Coen D.A. Stehouwer, Bjorn Winkens, Wubbo Mulder and P. Hugo M. van der Kuy. Assessing the strengths and weaknesses of a computer assisted medication review in hospitalized patients. International Journal of Hospital Pharmacy, 2017,2:6. DOI: 10.28933/IJHP-2017-10-0101 
2.Ananth kashyap, Rashmi N G, Rakshith U R, Hanumanthachar Joshi.Selective Serotonin Reuptake Inhibitors Induced Serotonin Syndrome –A Case Report. International Journal of Hospital Pharmacy, 2017,2:7. DOI:10.28933/ijhp-2017-10-1101

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Open Access
International Journal of Hospital Pharmacy is a peer reviewed open access journal publishing research manuscripts, review articles, case reports, editorials, letters to the editor in Hospital Pharmacy (indexing details).

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International Journal of Hospital Pharmacy

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