Drug Induced-Stevens Johnson Syndrome


Drug Induced-Stevens Johnson Syndrome


Sileabat Aschalew1, Sisay Legesse1, and Lidya Hailu2

1Arba Minch University, Department of Public Health
2Arba Minch University, Department of Industrial Chemistry


Background: Stevens–Johnson syndrome (SJS) is one of the severe forms of cutaneous adverse drug reactions. Despite it is rare, SJS is highly weakening and life-threatening illness commonly occurs as a result of medications, which is characterized by fever and mucocutaneous lesions leading to necrosis and sloughing of the epidermis.
Objectives: This case report professionally provide feedback on clinical practice guidelines, offer a framework for early signals of effectiveness, adverse events; and to share the case for medical, scientific or educational purposes.
Methods: This is an observational type of case report which we observed in Arba Minch University Students’ Clinic during outpatient diagnosis.
Discussion: Despite ciprofloxacin induced SJS had reported in different areas by different scholars with different duration on antibiotics, clinical manifestations, duration of recovery and complications; but itis the first report in Ethiopia.
Conclusion: This case concludes that severe hypersensitivity reactions like SJS can be caused by ciprofloxacin use which can be potentially life threatening. Therefore, identifying medications causing SJS is of paramount importance to withdraw it immediately and for additional treatment.


Keywords: Ciprofloxacin; Stevens Johnson Syndrome; Medications; Adverse drug reactions.

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How to cite this article:
Sileabat Aschalew, Sisay Legesse, and Lidya Hailu. Drug Induced-Stevens Johnson Syndrome .International Research Journal of Public Health, 2020; 4:40.


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