Research Article of Journal of Herbal Medicine Research
Evaluation of Antibacterial Activity of Shigru Patra Churna
Dr. Abhijeet D. Kumbhar1*, Dr. Vamsikrishna G. K.1, Dr. Surekha Khot2.
1*P. G. Scholar; 1 Professor & HOD; 2Associate Professor;
Department of Post Graduate studies in Dravyaguna, Shri Shivayogeeshwar Rural Ayurvedic Medical College & Hospital, Inchal, Tahsil Soundatti, Dist. Belgavi.
Background: Shigru (Moringa Oleifera Lam.) is a well known drug in Ayurveda used for its Krimighna activity (ability to kill the pathogens). Acharya Charaka had mentioned Shigru in Krimighna Mahakashaya1. Nighantus had specifically mentioned Krimighna activity of Shigru Patra viz. Kaiyadeva Nighantu2, Raj Nighantu3 and Shaligram4 Nighantu. Therefore Patra churna (powder of leaves) is selected for evaluation of anti bacterial activity on the strains which affects a large number of population.
Methods : Shigru Patra churna at different concentrations viz. 5µl, 10µl, 25µl, 50µl and 75µl were tested for anti bacterial activity by Disc Diffusion method for 2 strains of Gram positive and 2 strains of Gram negative bacteria each, with DMSo (Dimethyl Sulphoxide) a neutral solvent. Zone of Inhibition was calculated.
Result : Shigru Patra inhibits growth of Staphylococcus aureus, Pseudomonas auringinosa and Escheria coli at higher concentrations of 50µl and 75µl and is resistant to Streptococcus mutans at all concentrations. Zone of inhibition was 13mm for Staphylococcus aureus, 12mm for Pseudomonas auringinosa and 15mm for Escheria coli and activity index were 0.86, 0.40 and 0.50 respectively.
Conclusion : Shigru Patra possess good anti bacterial activity against Staphylococcus aureus, Pseudomonas auringinosa and Escheria coli.
Keywords: Shigru, Moringa oleifera Lam, Zone of Inhibition, Anti bacterial, Activity Index, Bacteria
How to cite this article:
Abhijeet D. Kumbhar, Dr. Vamsikrishna G. K., Dr. Surekha Khot.EVALUATION OF ANTIBACTERIAL ACTIVITY OF SHIGRU PATRA CHURNA. Journal of Herbal Medicine Research, 2018,3:23.
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