Terpenoids and steroids isolated from Calophyllum polyanthum


Terpenoids and steroids isolated from Calophyllum polyanthum


CAO Ting-ting1, LI Xu1, YANG Teng-yun2*, LI Dan-dan3*

1School of Pharmaceutical Science and Yunnan Key Laboratory of Pharmacology of Natural Products, Kunming Medical University, Kunming 650500, Yunnan, PR. China. 2Department of Sports Medicine, The First Affiliated Hospital of Kunming Medical University, Kunming 650032, Yunnan, PR. China. 3The First Affiliated Hospital of Dali University, Dali 671000, Yunnan, PR. China.


Three triterpenoids, one diterpenoid and two steroids were isolated from the aerial parts of Calophyllum polyathum. The structures of these compounds were determined by 1D NMR and mass spectroscopic data. Among them, compounds 1, 3, and 4 was obtained for the first time from Calophyllum polyathum.


Keywords: Calophyllum polyathum; Guttiferae; Terpenoid; Steroid; Structure elucidation

Free Full-text PDF


How to cite this article:

CAO Ting-ting, LI Xu, YANG Teng-yun, LI Dan-dan. Terpenoids and steroids isolated from Calophyllum polyanthum. Journal of Pharmaceutical Research and Reviews, 2021; 5:21. DOI: 10.28933/jprr-2021-03-1005


References:

1. Zhong, H., Ruan, J. L., Yao, Q. Q. (2010). Two new 4-arylcoumarins from the seeds of Calo-phyllum polyanthum. J Asian Nat Prod Res, 12(7): 562-568.
2. Ito, C., Matsui, T., Kobayashi, T., Tokuda, H., Shanmugam, S., Itoigawa, M. (2018). Cancer chemopreventive activity of xanthones from Calophyllum elatum. Nat Prod Commun. 13(4): 447-449.
3. Xiao, Q., Zeng, Y. B., Mei, W. L., Zhao, Y. X., Deng, Y. Y., Dai, H. F. (2008). Cytotoxic prenylated xanthones from Calophyllum ino-phyllum. J Asian Nat Prod Res 10(10): 993-997.
4. Cuesta-Rubio, O., Oubada, A., Bello, A., Maes, L., Cos, P., Monzote, L. (2015). Antimicrobial assessment of resins from Calophyllum antilla-num and Calophyllum inophyllum. Phytother Res, 29 (12): 1991-1994.
5. Ee, G. C. L., Jong, V. Y. M., Sukari, M. A., Rahmani, M., & Kua, A. S. M. (2009). Xan-thones from Calophyllum inophyllum. Pertanika J Sci Technol, 17 (2): 307-312.
6. Daud, S. B., Cheng, G., Malek, E. A., Ahmad, Z., Hashim, N. M., See, I. (2016). A new pyranoxanthone from the stem bark of Calophyllum buxifolium. Chem Nat Compd, 52(5): 807-809.
7. Bernabé-Antonio, A., Álvarez-Berber, L. P., Cruz-Sosa, F. (2014). Biological importance of phytochemicals from Calophyllum brasiliense Cambess. Annu Res. Rev Biol, 4 (10): 1502-1517.
8. Chaturvedula, V. S., Norris, A., Miller, J. S., Ratovoson, F., Andriantsiferana, R., Rasamison, V. E., Kingston, D. G. (2006). Cytotoxic diterpenes from Cassipourea madagascarien-sis from the Madagascar rainforest. J Nat Prod, 69(2): 287–289.
9. Li, X. H., Yang, W. Y., Wang, J., (2019). Study on chemical constituents of Dai traditional medicine “Ya-Haiba” (Phyllanthus niruri L.). Asia-Pac Trad Med, 15(02): 59-63.
10. El-Seedi H. R. (2005). Antimicrobial triterpenes from Poulsenia armata Miq. Standl. Nat Prod Res, 19(2): 197–202.
11. Leong, Y. W., Harrison, L. J. (1999). (20R, 23E)-Eupha-8,23-diene-3β,25-diol from Tripe-talum cymosum. Phytochemistry, 50 (5): 849-857.
12. Chundattu, S. J., Agrawal, V. K., Ganesh, N. (2016). Phytochemical investigation of Calotro-pis procera. Arab J Chem, 9: S230-S234.