Open Journal of Gastroenterology and Hepatology


Endoscopic Outcome of non complicated Gastric Ulcer following Standard Medical Treatment in sub-Saharan African Population

Research Article of Open Journal of Gastroenterology and Hepatology Endoscopic Outcome of non complicated Gastric Ulcer following Standard Medical Treatment in sub-Saharan African Population Kowo MP1, Essouma M1, Ndjitoyap Ndam AW1, Wembe Sop BD2, Kenfack GU1, Guekam Ouamba P2, Ndjitoyap Ndam EC1, Njoya O1, Ankouane Andoulo F1 1Faculty of Medicine and Biomedical Sciences, University of Yaounde I, Cameroon; 2Université des Montagnes Banganté Cameroon Background.The endoscopic outcome of gastric ulcers is not well described in sub-Saharan Africa. This study was therefore conducted in order to track the endoscopic outcome of non complicated gastric ulcers following standard medical treatment in  sub-Saharan African population. Methods.This was a prospective cohort study conducted from January to July 2018 in three tertiary healthcare centers in Yaounde (Cameroon).Gastric ulcers and gastric H. pylori infection were diagnosed and monitored by upper digestive endoscopy performed before and at least four weeks following treatment with proton pump inhibitors alone or combined with antibiotics depending on H. pylori status.  A complete case analysis was done using the SPSS software, version 21.0. p-values ≤0.05 were considered as significant. Results. Ninety-six patients (54.2% males) with a mean age of 55.3 ± 14.9 years were initially enrolled. In most patients, the ulcer frequently was unique (76%) and the antrum was the commonest localization 76 (79.2%). Among patients with H. pylori infection, the quadruple therapy was the most prescribed treatment 41 (87.2%) patients. There were 60 (62.5%) subjects lost to follow-up. Of the 36 (37.5%) patients who underwent repeat endoscopy, 26 (72.2%) had ulcer healing and 8/13 patients had successful H. pylori eradication. A delay of repeat endoscopy >8 weeks was the only predictor of non-healing of the ulcer: relative risk 0.6[95% CI: 0.3-1.08], p = 0.05. Conclusion.Ulcer healing was found in nearly 2/3 of patients and H. pylori eradication in almost ¾ of patients. This study ...

Gastric Outlet Obstruction: Transform in Etiogenesis

Research Article of Open Journal of Gastroenterology and Hepatology GASTRIC OUTLET OBSTRUCTION: TRANSFORM IN ETIOGENESIS: STUDY FROM NORTHERN RAJASTHAN ZUBIN PRADEEP SHARMA, RAVINDRA SHARMA, DIVYA SHARMA, SANTOSH YADAV Department of Gastroenterology, Aditya Hospital And Gastroenterology Centre, Rajasthan, India Objective: To determine the frequency of various etiologies of Gastric Outlet Obstruction in Northern part of Rajasthan, India. Design & Duration: Prospective study carried out from March 2018 to March 2019. Methodology: The data of all the patients who presented with the features of Gastric Outlet Obstruction during the above mentioned period was collected. This data was analyzed with specific reference to recent trends in its etiology. This change in trend was compared with other local and international studies. Results: Fifty patients were included in the study. All patients underwent upper GI endoscopy and biopsy; 40 cases were diagnosed by this method and the remaining by CT scan. Gastric carcinoma was the most common cause of Gastric Outlet Obstruction seen in 36% of the cases. The next common etiology was peptic ulcer disease which was responsible for 32% of the patients. Conclusion: The ratio between benign and malignant etiologies of Gastric Outlet Obstruction is showing a gradual change in favour of malignant lesions. This change is similar to the trends reported in the western literature. Keywords: Gastric Outlet Obstruction, etiology, Gastric Carcinoma, Peptic Ulcer disease ...

Clinical Picture of Celiac disease: Experience from a health care provider in Arabia

Research Article of Open Journal of Gastroenterology and Hepatology Clinical Picture of Celiac disease: Experience from a health care provider in Arabia Diamond Joy, MD, MSc, FRCP (UK)1,  Fuad Y Maufa, MD1,  Nassir Al Hayaf, MD1,  Martin Diamond2,3,  Sayed Z Haji, MD2,  Carole A Merriwether4 1Gastroenterology department, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia. 2Internal Medicine department, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia. 3Medical Student, Cardiff Medical School, United Kingdom.4Population health department. Gastroenterology department, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia. Background:  Most studies describing clinical features and associations of celiac disease come from the studies conducted in the western world. Our aim was to determine the clinical features and associations of Celiac disease from our centre serving a Middle East population in Saudi Arabia. Methods: This retrospective study was conducted in a health care provider serving the Eastern Province of Saudi Arabia. All patients with biopsy-confirmed celiac disease receiving health care at our centre between April 2002 and December 2018 were identified. Individual case records were reviewed. In addition, the Slicer Dicer function was also used from the Electronic medical health record [EPIC] for analysing the clinical features and associations. Results: We analyzed the clinical features of 149 patients with Celiac disease. 66% of these were females. There was progressively increased yield of confirmed Celiac disease over the study period. This was paralleled by an increase in TTG antibody tests performed year by year. 77 (51.6%) patients had gastrointestinal symptoms. 26% of patients had iron deficiency anemia. 24 patients (16%) had diabetes, of which 46% were type 2. 18 (12%) patients had osteoporosis or osteopenia, and 28 (19%) had various skin diseases. Conclusion: In Saudi Arabia, celiac disease is being increasingly recognized, largely because of increased awareness and increasing TTG antibody testing. Many patients present with non-gastrointestinal symptoms ...

Polypoid Collagenous Colitis: A Microscopic Colitis with a Macroscopic Appearance

Case Report of Open Journal of Gastroenterology and Hepatology Polypoid Collagenous Colitis: A Microscopic Colitis with a Macroscopic Appearance David Gay, MD1, Darcy Broughel-Baer, DO2, Rachel Hudacko, MD3 1Department of Pathology, Immunology, and Laboratory Medicine, Rutgers New Jersey Medical School, Medical Science Building C-579, 185 South Orange Avenue, Newark, New Jersey 07103 2Department of Pathology, Orange Regional Medical Center, 707 East Main Street, Middletown, New York 10940 3Department of Pathology and Laboratory Medicine, Rutgers Robert Wood Johnson Medical School, MEB 212, 125 Paterson Street, New Brunswick, New Jersey 08901 Collagenous colitis is a type of microscopic colitis which was originally named based on specific histologic features and the lack of macroscopic abnormalities in the colon. However, there are reports in the literature that describe various macroscopic findings on colonoscopy in patients with histologically confirmed microscopic colitis. We report a case of collagenous colitis that was characterized by a diffusely polypoid colonic mucosa on gross examination of a right hemicolectomy specimen that was performed for a benign neoplasm in a 72 year old man. It is important for endoscopists to be aware of the various macroscopic abnormalities that may be present in this “microscopic” disease. Keywords: Collagenous colitis (CC), microscopic colitis (MC), colon polyps, endoscopy ...

Dr. Mohammed Naeem
Chair, Patient Safety Reporting/Consultant Pediatric Intensivist/ Head PICU (A)/ Assistant Professor, Dept. of Pediatrics. Ministry National Guard Health Affairs Riyadh, Saudi Arabia

Dr Toru Ishikawa
Gastroenterology, Saiseikai Niigata Daini Hospital

Dr. George Paraskevas
Associate Professor of Anatomy Orthopedic Surgeon, Department of AnatomyMedical School, Aristotle University of Thessaloniki, Post Box: 300, Post Code: 54124, Thessaloniki, Greece

Dr. Mahaboob Vali Shaik
Assistant Professor/Senior Scientist, Department of Genetics & stem cell Research, Narayana Medical College & Hospitals

Dr. Ifeadike Chigozie Ozoemena
Associate Professor, Department of Community Medicine, Faculty of Medicine, Nnamdi Azikiwe University

Dr. Eduardo de Moura GH
Professor, niversity of São Paulo School of Medicine, São Paulo, Brazil

Manuscript Title: The title should be a brief phrase.

Author Information: List full names and affiliation of all authors, including Emails and phone numbers of corresponding author.

Abstract: The abstract should be less than 500 words. Following abstract, a list of keywords and abbreviations should be added. The keywords should be no more than 10. Abbreviation are only used for non standard and long terms.

Introduction: The introduction should included a clear statement of current problems.

Materials and Methods: This section should be clearly described.

Results and discussion: Authors may put results and discussion into a single section or show them separately.

Acknowledgement: This section includes a brief acknowledgment of people, grant details, funds

References: References should be listed in a numbered citation order at the end of the manuscript. DOIs and links to referenced articles should be added if available. Abstracts and talks for conferences or papers not yet accepted should not be cited. Examples Published Papers: 

1.Gomes, K.K.L; Lima, A.A.F. Living Style of Diabetic Patients Type.Open Journal of Gastroenterology and Hepatology, 2018, 1:5. DOI:10.28933/ojgh-2018-05-1005

Tables and figures: Tables should be used at a minimum with a short descriptive title. The preferred file formats for Figures/Graphics are GIF, TIFF, JPEG or PowerPoint.

Publication fee: The authors will be contacted about the publication fee after a manuscript have been accepted.

Proofreading and Publication: A proof will be sent to the corresponding author before publication. Authors should carefully read the proof to avoid any errors and return the proof to the editorial office. Editorial office will publish the article shortly and send a notice to authors with the links of the paper.

Open Access

Open Journal of Gastroenterology and Hepatology is a peer reviewed open access journal publishing research manuscripts, review articles, editorials, letters to the editor in Gastroenterology and Hepatology  (Indexing information).

Peer Review

To ensure the quality of the publications, all submitted manuscripts will be peer-reviewed by invited experts in the field. The decisions of editors will be made based on the comments of the reviewers.

Rapid Publication

Time to first decision: within 2 days for initial decision without review, 18 days with review; Time to publication: Accepted articles will be published online within 2 days, and final corrected versions by authors will be accessible within 5 days.  More details....

Rapid Response Team

Please feel free to contact our rapid response team if you have any questions. Our customer representative will answer your questions shortly.

Open Journal of Gastroenterology and Hepatology LOGO1

Loading