Open Journal of Physiology and Pathophysiology


Research Article of Open Journal of Physiology and Pathophysiology INCIDENCE OF MENTAL RETARDATION IN RECIFE POPULATION: AN ANALYSIS FROM NATIONAL HEALTH INDICATORS Eduardo Tomilheiro de Farias ¹*; Mateus Cotias Filizola2; Wirley Matias Alves Martins Duarte3; William Barros Agrelli Girão4; Lívia Lócio Rosado de Oliveira 5; Edmundo de Oliveira Gaudêncio6 1,2,4Estudante do Curso de Medicina da Universidade Federal de Pernambuco – UFPE; 5Estudante do Curso de Medicina da Universidade Pernambucana de Saúde 3Estudante do Curso de Medicina da Universidade UFCG 6Professor Associado II da Universidade Federal de Campina Grande Introduction: Mental retardation is characterized by the arrest or incomplete development of intellectual functioning, essentially by a impairment of cognitive functions, language, motor skills and social behavior. The prevalence rate traditionally quoted is 1% of the young population. Objective: To describe the incidence / prevalence data in cases of mental retardation between 2014 and 2018 by sample of the type of clinical care, gender and age group in the city of Recife. Methodology: This is a study in secondary databases, through the Basic Data indicators of Brazil, a tool of the health information system, using quantitative analysis of the variables. Results: We analyzed data regarding hospitalizations between 2014 and 2018. We observed that Recife had 93.7% of hospital admissions in Pernambuco, and the total amount spent by public coffers in 2018 was 31% higher than 2017, however, 24.2% lower than the average of the analyzed period. There is an equivalence in elective (56%) and urgent (46%) hospitalizations. The most frequently hospitalized age group was 20 to 29 years old (33.1%), followed by 30 to 39 years old (22.7%); The brown color presented 78.1% of the hospitalizations and 61% of the hospitalizations corresponded to the male gender. The average hospital stay of 2018 was the highest in the historical series (17.7), 46.7% higher ...

Analysis of the functional independence of patients with amiotrophic lateral sclerosis

Research Article of Open Journal of Physiology and Pathophysiology Analysis of the functional independence of patients with amiotrophic lateral sclerosis Silva, J.P.R1; Santiago Junior, J.B2; Santos, E.L3; Costa, I.M.P.F4; Mendonça, D.M.F5 1Physiotherapy Student, UFS, 2Biological Sciences Student, UFS; 3Biological Sciences Student, UFS; 4Professor, Researcher at the Physical Therapy Department, UFS; 5Professor, Researcher at the Biosciences Department, UFS Introduction: Amyotrophic Lateral Sclerosis (ALS) is a progressive neurodegenerative disease characterized by selective degeneration of motoneurons in the cortex, brain stem and spinal cord. Diversity in the clinical condition is a well recognized feature of the disease. Functional Independence (FI) relates to functional activities, identified by the individual as essential for the preservation of their physical and psychological well-being. Patients diagnosed with ALS have direct effects on functionality and well-being. Objective: Analyze the FI index of patients with ALS, living in Aracaju/SE. Methods: This is an analytical, descriptive, cross-sectional study, with sampling for convenience. Data collection was performed in the patients’ homes and Functional Independence Measure (MIF) was used to measure functional independence levels. Results and Discussion: Patients of both sexes were evaluated, being 75% male and 25% female. The mean age was 63.2 years and the time of diagnosis was on average of 4.7 years. Of these, 50% breathed in ambient air and 50% used mechanical ventilation assistants, 75% were assisted with auxiliary devices and 25% were restricted to the bed. All patients receive medical care and 25% of them are assisted by a multidisciplinary team. MIF presented a mean of 65.25 points in total, indicating a dependence between modified and complete in the individuals studied. Chronic diseases such as ALS produce significant repercussions on IF, but with preservation of cognition and these are some of the main problems in the life of patients. Conclusion: Individuals affected by ALS have heterogeneous alterations, ...

Palliative care: toy therapy benefits of pediatric oncology

Review Article of Open Journal of Physiology and Pathophysiology Palliative care: toy therapy benefits of pediatric oncology Torres, R.L.N 1; Silva, M.H2; Melo, T.R.C3; Moura, A.G.R.M4; Maior, H.C.S5; Vasconcelos, J.L.A 6 1,2,3,4,5 Academic Baccalaureate in Nursing - - University Center Tabosa de Almeida (ASCES-UNITA); 6 Lecturer of the Bachelor in Nursing - 6Lecturer of the Bachelor in Nursing - University Center Tabosa de Almeida (ASCES-UNITA). Introduction: Palliative term means “calm ‘’ or” temporarily slow down evil ‘’, according to the World Health Organization (WHO). In this process, palliative care to cancer patients is given from the time of diagnosis, generating preventive actions primarily for the relief of pain of each individual. Pediatric patients often require a different palliative care. Given this, the Law No. 11,104, of March 21, 2005, establishes toy libraries installation in health facilities that offer pediatric care in detention regime. Objective: analyze the benefits of toy in pediatric oncology. Methodology: This is a literature review study, using the following electronic journals in databases: BDENF, LILACS, SciELO and Brazilian law. The descriptors used were Therapeutic Toy, Cancer, Palliative Care, Child oncopediatrica. The search took place 10-20 July 2017. Under the inclusion criteria for articles published between 2012 and 2016, written in Portuguese and in full text. Excluding the items that did not meet the theme. Results and Discussion: identified 98 publications, 12 of these met the inclusion criteria. The discussion of the play as a palliative care to cancer child, demonstrates to be relevant, since it is considered an important element in fighting the disease and treatment. The use of therapeutic play is seen as an essential tool in the treatment because it facilitates the understanding of the procedures and acceptance in the treatment and minimize the anxiety, stress and fear, also contributing to the interaction, the welfare and ...

Case report – human tegumentary leishamaniasis

Research Article of Open Journal of Physiology and Pathophysiology Case report – human tegumentary leishamaniasis Rocha F.J.S.1, Pereira C.L.D.1, Melo R.R.2, Soares C.R.P.3, Melo F.L.3, Giorgio S.4 1Department of Tropical Medicine, Federal University of Pernambuco, Postal Code: 1235, 50670-901 Cidade Universitária, Recife, PE, Brazil. 2Dermatology - Hospital das Clínicas of Pernambuco / HC-UFPE. 3Research Center Aggeu Magalhães - CpqAM (Fiocruz Pernambuco). 4State University of Campinas - UNICAMP, Institute of Biology. Caixa Postal, 13.083-862. Campinas, SP. Introduction: Leishmaniasis is a serious public health problem in Brazil and in the world. It is considered one of the six most important infectious diseases in the world and is endemic in 88 countries. The objective of this study is an account of the case of a patient attended by Dermatology Department from Clinical Hospital at the Federal University of Pernambuco, which was admitted with clinical suspicion for leishmaniasis in the year 2013 and had your lesion evaluated through histopathological, molecular and also with stress and cellular inflammation markers, Hypoxia-inducible factor, HIF-1α. The patient had a lesion located in the nose, which was initially submitted to biopsy after four months of evolution. Subsequently, the material was submitted to the paraffinization procedure and after to included in the dermatology collection and analysis. Slides with sections of the material were stained with Hematoxylin / Eosin for histopathological analysis performed at the Hospital, and others were not stained for the immunohistochemical study, performed with peroxidase system and HIF-1α detection occurred in the nucleus and / or cytoplasm of macrophages and it was performed by Laboratory of Tropical Disease from Department of Biology at University of Campinas and analysis by molecular biology was done by deparafinisation of fragments and subsequent DNA extraction with Promega® kit followed by PCR performed at the Aggeu Magalhães-Recife research center. Histopathological medical report classified ...

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1. Avinaba Mukherjee, Sourav Sikdar, Anisur Rahman Khuda-Bukhsh. Evaluation of ameliorative potential of isolated flavonol fractions from Thuja occidentalis in lung cancer cells and in Benzo(a) pyrene induced lung toxicity in mice. International Journal of Traditional and Complementary Medicine, 2016; 1(1): 0001-0013. 
2. Vikas Gupta, Parveen Bansal, Junaid Niazi, Kamlesh Kohli, Pankaj Ghaiye. Anti-anxiety Activity of Citrus paradisi var. duncan Extracts in Swiss Albino Mice-A Preclinical Study. Journal of Herbal Medicine Research, 2016; 1(1): 0001-0006.

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Open Journal of Physiology and Pathophysiology