Obesity Induced by High Fat Diet Impairs Glucose Tolerance and Insulin Sensitivity in Rats
Introduction: Obesity is a chronic disease, besides a risk factor for cardiovascular diseases, nowadays, it is characterized as a worldwide epidemic. The food imbalance and physical inactivity are factors that contribute to the emergence of obesity as well as diabetes. Objective: To evaluate the injury on glucose tolerance and insulin sensitivity in obese rats induced by high fat diet. Methodology: Male Rats Wistar (8 weeks old) were submitted to the standard diet (chow group, 11.8% kcal-Lipids; n = 5) and dietary intervention with high fat diet during 8 weeks (HFD group, 58.4% kcal-Lipids; n= 5). It was evaluated the body weight weekly, and fasting and fed blood glucose. At the end of the experimental period, was measured the glucose tolerance, insulin sensitivity and gluconeogenesis. After the animal sacrifice, it was analyzed relative weight of white adipose tissue, as well as the adipocytes diameter (epididymal white adipose tissue) and circulating levels of leptin. Results and Discussion: The group HFD presented higher body weight (from the 2nd week of diet), an increase accumulation of epididymal and perirenal white adipose tissue. In addition, in these animals, it was observed a significant increase in the adipocytes diameter and the levels of leptin in plasma when compared to animals chow, indicating obesity with increased release of cytokines. In HFD group, the fasting blood glucose levels were significantly higher in the 6th week of high fat diet consumption compared to the chow group. Adding up to the frame of obesity, at the end of the 8th week of high fat diet consumption, the obese group had higher fasting plasma glucose in fed state, glucose intolerance, insulin resistance, as well as increased gluconeogenesis as compared with the chow group. Conclusion: Obesity with adipocyte hypertrophy, induced by high fat diet, induces glycemic damages, as the elevation of blood…
Consumption of High Fat Diet Induces Obesity Associated to Hepatic Steatosis in Rats
Introduction: The high intake of carbohydrates and lipids is one of factors that contribute to the onset of Metabolic Syndrome (MetS), a complex clinical situation which brings together, besides obesity, several cardiovascular and metabolic risk factors, including non-alcoholic fatty liver disease (NAFLD). Objective: To develop a hyperlipidemic dietetic animal model to obesity associated with NAFLD. Methodology: Male Rats Wistar (8 weeks old) were submitted to the standard diet (chow group, 11,8% kcal- lipids) and hypercaloric and hyperlipidemic during 8 weeks (HFD group, 58,4% kcal-lipids). After the dietary intervention, body weight, plasma and hepatic lipid profile (triglycerides, total cholesterol, VLDL and fatty acids) and adiposity index were evaluated. Moreover, histological assessment of hepatic lipid deposition and fibrosis, as well as the hepatic damage marker (alanine aminotransferase-ALT) were evaluated. Results and Discussion: Comparing to the chow group, HFD animals presented higher body weight, both in fasting and in the fed state, increased abdominal circumference, adiposity index, as well as plasma levels of total cholesterol and non-esterified fatty acids, characterizing the dietary phenotype of obesity. In addition, the HFD group had a significant decrease in brown adipose tissue, together with the lowest weight loss induced by 16h overnight fasting, suggesting a decrease in energy expenditure. In the liver, the HFD group presented a significant increase in the levels of triglycerides, cholesterol, VLDL and non-esterified fatty acids, and, qualitatively, increased lipid deposition and fibrosis. Together, these results associated with increased plasma ALT activity indicate NAFLD with hepatocyte damage. Conclusion: A high fat diet intake induces comorbidities that characterize MetS, such as obesity associated with decreased energy expenditure, as well as NAFLD.
Analysis of Hepatotoxic and Lipidic Profiles in Students of an Institution of Private Higher Education, Since the Use of Literacy Drugs
A Introduction: In most countries, drug use is regulated by official bodies that determine which substances can be consumed. However, in many countries, alcoholic beverages and cigarettes, for example, are licit drugs although their consumption is usually of no medicinal purpose. According to the World Health Organization, alcohol dependence affects about 10 to 12% of the world’s population and alcohol is recognized as a major cause of mortality and disability. One in 20 deaths is attributed to the consumption of alcohol, a licit drug that kills more than AIDS, tuberculosis and violence together, warns the WHO. Objective: The objective of this project is to analyze hepatotoxic and lipid profiles in students of a private higher education institution, due to the use of licit drugs. Metodology: The study was a cross-sectional, experimental, quantitative and qualitative study, in which the hepatic and lipid biochemical aspects of licit drug users and the sample profile were evaluated based on a questionnaire, the total sample of the study added 300 individuals representing the population total. Results and Discussion: Based on the results it was verified that 205 (68.3%) of the students answered that they consumed at least one or more drugs in the month, being only alcohol, and only 95 (31.7%) did not use any drugs damn it. Among women, 218 (72.7%), drink and only, 28 (11.3%) do not drink. Regarding men, 27 (50%) drink and 27 (50%) do not drink. The level of consumption was observed that, 139 (46.3) consume five or more doses of alcoholic beverage on one occasion, and 83 (27.8%) drink more than once in the month. Conclusion: According to the data, it is inferred that there was a strong incidence in the consumption of alcohol, since the Tobacco did not have significant samples
Hematological Change in Dogs Infected by Babesia Canis From Recife/Pernambuco
Introduction: The canine babesiosis is a disease caused by the intra-erythrocyte hematozoa Babesia canis, B. gibsoni and B. vogeli, mainly transmitted by Rhipicefalus sanguineus tick. In Brazil, the most common species is B. canis. Cases of canine babesiosis have been reported in several Brazilian states, and may cause serious damage to the health of animals. Objective: this study aims to analyze the hematological alterations of dogs treated at a veterinary clinic. Methodology: the research was retrospective, exploratory, descriptive and cross-sectional with quantitative-qualitative approach, and it was carried out at the clinic Bicho Estimado – Cordeiro, Recife-PE. Data collection was performed in the database of the Clinic laboratory, where reports of complete blood count and hematozoal examination were consulted, referring to the period from May 2012 to December 2014. Results: 716 laboratory reports were analyzed. A mean positivity of 20.11% was found for canine babesiosis, diagnosed by the blood draw technique stained by Giemsa. With regard to the hemogram, the following results were obtained: erythrocytes with an average value of 5.36 million/μL [reference value (VR)= 5,5 to 8,5] and platelets 183.5 thousand/μL (200-500 thousand/μL). Discussion: The hemogram showed the presence of anemia, with values of hemoglobin below the reference values. In the leukogram, monocytopenia and mild neutrophilia were observed. He also had thrombocytopenia and a high positivity for babesia. Conclusion: the results showed that babesiosis affects dogs of this region with a relevant frequency, causing alterations in some hematological parameters. The data indicate that the city has favorable conditions and an environment conducive to the contact of dogs with the transmitting agent, an important fact to outline future prevention, education and treatment strategies.
Psychological Care Occurs in Pre and Postoperative Cardiac Valve Replacement Surgery
Introduction: Cardiovascular diseases affect many individuals and their medical evaluation identifies the need for surgery, such as myocardial revascularization, valve replacement, among others. Cardiac valve replacement is a possibility for patients to promote their quality of life, which requires the performance of a multidisciplinary team, and the psychological support to the patient collaborates for its recovery. Objective: To describe how psychological care occurs in pre and postoperative cardiac valve replacement surgery. Methodology: Experience report. Results and discussion: In the preoperative period of this surgery, the psychologist performs an interview to evaluate the patient, analyzes whether he has a history of mental disorder and establishes a host and attachment for follow-up, and in the postoperative period, focuses on recovery and psychological support to the patient, aiming to raise awareness of the quality of life. Conclusion: The insertion of the psychologist in the health team is essential for the patient care in this surgery, offering psychological support and speech space to express the patient’s desires before surgery and the chronicity of this disease.
Prevalence of Obesity in Hypertensive Patients
Introduction: Obesity is an independent risk factor for cardiovascular diseases and plays a central role in the metabolic syndrome, which involves hypertension, insulin resistance and dyslipidemia. The prevalence of hypertension is about 3 times higher in obese patients. In the treatment of hypertension associated with obesity the decrease of the BMI plays central role in the reduction of the pressure. Objective: To investigate the prevalence of obesity in hypertensive patients. Methods: A descriptive cross-sectional study of the documental type with a quantitative approach was carried out from 150 medical records of adult hypertensive patients followed up by the HIPERDIA program in the first half of 2017 at the Pororoca basic health unit in the municipality of Santa Cecília -PB. The body mass index was used to classify the nutritional status. Results and Discussion: 51% female, 49% male. 10% adequate weight, 65% overweight and 25% obesity. The prevalence of obesity in the studied population was 25%, while 65% of the sample were overweight. Only a small part, 10%, was found as the proper weight. There was no discrepancy in the percentage of male and female users. Conclusion: The results of the present study show a high prevalence of overweight and obesity, reinforcing the need for strategies that promote the reduction of obesity among hypertensive individuals. For this, the identification of obesity should be part of the routine actions of basic attention to the health of the hypertensive ones.
Health Education in Systemic Arterial Hypertension: an Approach to Nursing
A Introduction: Systemic arterial hypertension is a multifactorial clinical condition characterized by elevated and sustained blood pressure levels, which when not adequately treated causes temporary and / or permanent complications. Constantly associated with injuries such as cerebrovascular disease, coronary artery disease, chronic heart failure and renal and vascular disease of extremities. Objective: Describe nursing care in systemic arterial hypertension, with emphasis on health education for patients and their families. Methodology: An integrative review was performed using articles as criteria between 2013 and 2017, combining the descriptors: nursing care, health education and hypertension, in the electronic databases Scientific Eletronic Library Online (SCIELO), Latin American and Caribbean Literature in Health Sciences (LILACS) and National Library of Medicine (MEDLINE). We selected 67 articles initially and after reading the titles and summaries of them, only 12 presented a relation with the researched topic. Being 02 from SCIELO, 05 from LILACS and 05 from MEDLINE. Results and Discussion: In the context of systemic arterial hypertension, the nurse should assist the client, assist him in controlling blood pressure levels and in the development of skills and attitudes that provide effective self-care, such as stimulating the modification of unfavorable habits. For this, it is essential that the interaction between professional and client takes place in an effective way, with the purpose of enabling adherence to treatment. As part of this process, in addition to individual monthly consultations it is necessary to have group activities addressing hypertension, guiding control measures and encouraging the continuity of treatment. Conclusion: It is up to the professional, therefore, to consider that the care given by him is not an imposition of knowledge, but rather an exchange of knowledge and trust, valuing the autonomy, the protagonism of the patient and the help of the family in the caring process.
Health Education on Hepatites HIV AIDS for Sex Workers
Introduction:The epidemic among young people, according to UNAIDS, the risks of HIV among adolescents and young people are greater when the age transition occurs in challenging environments, with insufficient access to food, education and housing and with high rates of violence. Perceptions of low infection risk, poor condom use and low rates of HIV testing persist among young people. UNAIDS epidemiological data from 25 countries shows that the total number of people aged 15-19 years living with HIV in these countries increased from approximately 800,000 in 2005 to 940,000 in 2015.1 Objectives: To promote health education on breast cancer, its manifestations, prevention and treatment for sex workers. Methodology: This is a participatory research, carried out by academics and professors of the Nursing undergraduate course of Uninassau and UFAL, in March 2017, at Quilombo Muquem in Joaquim Gomes, Alagoas, Nursing course, with the presence of 19 adolescents being 12 male and 7 female, between the ages of 12 and 17. Conclusion: After correlating each principle of the mandala to HEPATITES, HIV / AIDS, and showing the forms of transmission through the mandala of knowledge, there was a restlessness present in each adolescent, each wanted to expose some situation in relation to something similar to the ones hepatitis, HIV / AIDS, all knew, had a friend, relative who has or had some pathology cited. It was verified, in this experiment, the knowledge deficit of the group of quilombolas adolescents in relation to HIV AIDS Hepatitis. Many of them expressed concern about a quilombola teenager presenting some symptoms, according to them, spoke of the importance of how to correctly use the condom, wash hands and food well. We ended our health education by distributing condoms, explanatory leaflets on hepatitis, HIV AIDS.
Nursing Care for Individuals With HIV AIDS Under the Heideggerian Theory
Introduction: AIDS is a chronic communicable disease marked by strong impacts on the social, psychic and biological aspects related to the individual. In this scenario Heidegger approaches reflections on human care, which involve profound reforms in the magnitude of this action. It uses the phenomenological method to develop concepts about human existence and their relationships. On care we can highlight the relevance of the understanding of concepts addressed as dasein, Being-in-the-world, Inauthenticity, and healing promoting a humanized nursing care to the individual with AIDS. Objective: To characterize nursing care for individuals with HIV / AIDS in the light of Heideggerian theory. Method: integrative literarure review. We include studies with integral text in Portuguese, English and Spanish published in the period of 10 years, indexed in the databases: Lilacs, Medline, BDENF related to the thematic axis according to the optics of the authors. It carried out the research in the bases through the VHL using the intersection of the Descriptors in Health Sciences (DECS) adapted the URSI form in the construction of the results. The articles were organized by year of publication and classified by levels of evidence between I and VI, analyzed by 2 different evaluators, achieving agreement in the classification. Results and discussion: After the analysis and synthesis of the data, the selected articles were separated into thematic categories, arranged in tables of presentation, and graphic resources. One can observe the nursing care coupled with the perception of Heideggerian formulators of the exercises of humanized actions that seek to understand the human feelings and perceptions opening possibility of expression and adequacy of single and holistic care modifying the perspectives on the actions of caring.Conclusion: reflections on nursing care for individuals in chronic conditions in phenomenology, addressed changes capable of understanding their needs and promoting humanized care.
Actions of the Nurse to the Old Patient of Cataractor
Introduction: Cataract is a serious eye disease caused by opacification of the lens, a natural lens of the eye, responsible for focusing the light under the retina and Senile is considered a public health problem due to the large number of people with the disease, which every year increases and demands surgical intervention. With the technological advancement in health services and discourses about the quality of health care, nursing is faced with the need to act through clinical judgment, knowledge and scientific evidence in its practices. Objective: to know the actions of the nurse to the elderly patient with cataract. Methodology: This is a descriptive study, with a qualitative approach, carried out with nurses of the Altino Ventura Foundation in Recife, PE, in November 2015. The text discusses nursing care for elderly patients, emphasizing one of the visual changes which most affects this population, the cataract. Results and Discussion: The sample consisted of 13 nurses. Regarding the nurse’s assistance in the education of the elderly with cataract, 92% (n = 12) stressed that they prepare the patient for pre and postoperative care, while 85% (n = 11) said they prepare the companion to remain with the elderly patient during home care, followed by 100% (n = 13) in the guidelines to the companion regarding the adequate care to the elderly in the pre and postoperative period. It is indispensable the nurse needs to identify the situations of risk and to take the prophylactic or control measures as early as possible. Conclusion: This study contributes to the nurses’ reflection on the relevance of the nursing consultation, focusing on the knowledge of their patients, as well as the care to be provided to them. Therefore, it is suggested the development of research focusing on the importance of this care to patients with…