International Congress 2018

Introduction: Information is a fundamental element in the analysis of health situations, because they offer subsidies for the planning and organization of services. At the end of 2015 new cases of children born with microcephaly associated with Zika Virus infection were registered. These children were introduced into the network of attention to the disabled person for early stimulation and developmental follow-up. It is hoped that the record of the attention given to these children will be correctly made in the medical records, which are the formal instruments of the interventions made by the professionals. Objectives: To describe the quality of records made of medical records of children diagnosed with microcephaly accompanied at a level III Specialized Rehabilitation Center in the state of Alagoas. Method: This is a descriptive and cross-sectional research, where the records of the secondary data were analyzed in medical records of children diagnosed with microcephaly, accompanied at a specialties center. It were monitored the filling of related variables: age, gender, cephalic perimeter (CP) and Neonatal Screening Tests (NSTs); The origin and infections related to the gestational period of the mothers of these children. Results: A total of 30 medical records were evaluated, where they presented fragility in the filling, being the variables related to origin and sociodemographic aspects the most precarious. Discussion: It was verified the absence of exams recommended by the Ministry of Health, the records of the conducts were not clearly described, besides the absence of a standardized evaluation form. Conclusion: It can be evidenced that there is precariousness in the filling of documents that characterize the monitoring of children with microcephaly in a specialized rehabilitation center, preventing the delineation of the sociodemographic profile of the users, as well as the correct mapping of the origin of the cases. This lack of data limits correct…

Introduction: Breast cancer is a serious public health problem, due to its high incidence, morbidity, mortality and its high cost of treatment. It is the second most frequent type of cancer in Brazil and the world and the most frequent among women. It is perceived that its incidence is higher in developing countries. In Brazil, breast cancer mortality rates remain high because the disease is still diagnosed in advanced stages. Objective: To describe the epidemiological profile of women with breast cancer, in Pernambuco, from 2009 to 2014. Method: A descriptive cross-sectional study was carried out based on the quantitative data from the public domain of the Ministry of Health, referring to the incidence of breast cancer from July 2009 to February 2014. Only Cases of malignant neoplasm in women, considering the following variables: race, schooling, age group and histopathological grade. Results and discussion: During the period considered for data collection, there were 2,281 cases of breast cancer in the Pernambuco Region, with an increasing trend over the years. Regarding the age group, the majority of women (17%) were older than 70 years at the time of diagnosis of malignant lesions, followed by women between 50 and 54 years (14%). Regarding education, 87% is ignored, followed by incomplete elementary education (6%). Brown women (26%) represent the largest part of the contingent diagnosed. Regarding the histological grade, 67% was invaluable, while grades II and III represent 31%. Conclusion: It is evident the need for continuity in investments in the development of comprehensive actions for the control of cancer, in the different levels of performance, as well as the continuity of feeding of the Information Systems, since it is knowing its epidemiological profile through the years that the actions May be better elaborated.

Introduction: Diabetes Mellitus (DM) is a disease, which affects large populations the state of Pernambuco, becoming a public health problem. People with this disease who are seeking care in public, can also receive care in agreements networks of the Unified Health System (SUS), which receives financial transfers from the Ministry of Health, through its three levels: Federal, State and County. DM uncontrolled was responsible for 30,106 hospitalizations in the past 5 years, bringing costs that could be avoided. Objective: present the annual costs of hospitalizations for DM in the public and private system of the state of SUS and Pernambuco. Methodology: This is um-descriptive study with cross-section from the public domain data available in the system Information SUS Hospital- SIH / SUS processed by DATASUS Diabetes mellitus. Data collection was carried out considering the years 2012 to 2016, using the expenditure data with admissions of derivative financial resources. To analyze the data we used the absolute values. Results and Discussion: In the period studied the total value dand used funds was R$ 20,545,949.98. The value used in 2012 was R$ 3,895,248.58 in 2013 R$ 4,516,990.86 in 2014 R$ 4,275,578.10 in 2015 R$ 3,837,742.69 in 2016 and R$ 4,020,389.75. The age group with more admissions were people between 60 and 79 years, totaling 13,796 cases, of both sexes. These quantitative belong to a network of 237 health facilities that are distributed throughout the state. Conclusion: With the improvement of health policy strategies in primary care, proper allocation of resources and efficiency in administration can achieve a reduction in the number of illnesses, thus reducing the value used to the hospitalization.

Introdução: A Política Nacional de Atenção Integral à Saúde do Homem foi criada em 2009, com a finalidade de qualificar a saúde da população masculina na perspectiva de linhas de cuidado que resguardem a integralidade da atenção. Objetivo: Diante dessa perspectiva, a finalidade do presente trabalho será relatar a experiência em educação em saúde como facilitadores de oficinas em saúde do homem na Zona da Mata Norte de Pernambuco. Metodologia: Esse estudo trata-se de um relato de experiência, de um grupo de residentes em Saúde Coletiva, na facilitação das oficinas de implantação do Guia de Saúde do Homem para Agentes Comunitários de Saúde, que foram realizadas nos 10 municípios que compõem a XII Gerência Regional de Saúde, no mês de novembro de 2016. Resultados e Discussão: Segundo o Cadastro Nacional de Estabelecimentos de Saúde, a XII Gerência Regional de Saúde apresenta 614 Agentes Comunitários de Saúde, porém participaram das oficinas 317 (52%). As oficinas foram idealizadas de maneira que fosse possível aproveitar o conhecimento advindo das vivências cotidianas dos participantes em seus territórios, a respeito do público masculino. Foram utilizadas dinâmicas de grupo, apresentada a Política Nacional de Atenção Integral à Saúde do Homem e, posteriormente houve a apresentação expositiva com exemplos da realidade, com vídeos e gravuras, para que pudessem fomentar a utilização do Guia de Saúde do homem. Ao término de cada oficina, foi lançada uma proposta aos municípios, que os mesmos fizessem ações focais em seus territórios que remetessem a um acolhimento melhor desse homem, para que posteriormente as experiências fossem apresentadas nem um fórum. Conclusão: Houve uma participação significativa dos profissionais, o que proporcionou um espaço favorável à troca de experiências e conhecimentos e a proposta de apresentação das ações focais no fórum, fomentou uma expectativa positiva na maioria dos grupos capacitados.

Over tOver the past 50 years, the role of pharmacists has evolved along with the health care needs of our population. In addition to dispensing medications and ensuring patient safety, today’s pharmacists are taking a larger role as medical counselors, educators and advocates. They are integral part of the health care team, and are among the most trusted and accessible health care professionals. This accessibility allows them to perform more patient care activities, including counseling, medication management, and preventive care screenings. Beyond the care provided to individual patients, pharmacists have expanded their reach to influence the public health of communities. A pharmacist is uniquely positioned to provide disease state management through appropriate medication therapy management that has been demonstrated to improve patient outcomes and decrease overall health care costs. This role is more important than ever as the environment is demanding new practice and payment models that are required to further optimize care and outcomes while addressing the unsustainable increases in health care costs.

Introduction: Diabetes Mellitus is one of the most common chronic diseases that affects humans in all stages of social and economic development, representing a big threat for the health of all the Brazilians. Objectives: Analyze epidemiologic profile of DM in the state of Pernambuco from 2002 to 2012 Methodology: It’s a retrospective study of epidemiologic nature with descriptive and quantitative approach. Data was provided by Hiperdia, avaiable at Departamento de Informática do Sistema Único de Saúde (DATASUS). The variables of this study are: Type of Diabetes, year, age, gender and amputation of diabetic foot. Results and Discussions: From 15.856 people with DM, 75,32% have DM Type2. The year of 2004 represented the lower occurrence rate of the disease for Type 1 (3,07%) and for Type 2 (3,86%). In the years of 2009 and 2002 the ocurrence number was higher, with 13,14% for Type 1 and 17,28% for Type 2. Both Types 1 and 2 represents de major occurrence in the age between 50 and 59 years old. However, Type 1 is less frequent in people with at least 80 years old while Type 2 is less frequent in the age between 15 and 19 years old. With respect to gender both Types are more common in women, with (61,96%) for Type 1 and (63,92%) for Type 2. In relation to people that suffered amputation of diabetic foot, 2,59% are Type 1 and 1,73% are Type 2, it brings the attention due to the fact that Type 2 DM is the most common Type. Conclusion: The understanding of DM epidemiologic scenario is important for acting directly at the most vulnerable social categories with efforts to promote and recover the health within completeness patterns.

Introduction: Brazilian flora has a great biodiversity and some of these plants are used in folk medicine. Avicennia schaueriana, popularly known as black mangrove, is an endemic specie of mangrove vegetation belonging to the Acanthaceae family. The species of the genus Avicennia are widely used by traditional communities for the treatment of tumors, rheumatism, ulcers and wound healing. Objectives: To evaluate the antioxidant and gastroprotective properties of the ethyl acetate extract of Avicennia schaueriana. Methodology: The ethyl acetate extract of the leaves of A. schaueriana (As-AcEOt) was obtained by maceration, and afterwards the phytochemical prospecting was evaluated by thin layer chromatography (TCL). The antioxidant potential of the As-AcEOt was evaluated by free radical scavenging method ABTS+ (2,2-azobis – (3-ethylbenzthiazoline-6-sulfonate). The gastroprotective activity of As-AcEOt (50, 100 and 200 mg/kg) was analyzed by the ethanol-induced ulcer method in Wistar rats. The myeloperoxidase (MPO) levels and histopathological analysis were evaluated in gastric mucosa of the animals treated with As-AcEOt submitted to the model of ulcer induced by ethanol. Results and Discussion: Through TCL was observed the presence of terpenoids, flavonoids and tannins in the extract. The As-AcEOt exhibited antioxidant activity with 73.23% inhibition of the radical ABTS+. In the gastroprotective activity, the As-AcEOt reduced the ulcerative lesion index (ULI), with percentages of ULI of 83.8, 88.5 and 86.9% for the doses of 50, 100 and 200 mg/kg, respectively. The histological analysis showed that As-AcEOt preserved the gastric pits and it did not present hemorrhage and edema. Conclusion: This research showed that As-AcEOt has gastroprotective property, which may be related to antioxidant capacity of the phenolic compounds present in the extract. These results corroborate with the indication of popular use of this species in the treatment of gastric ulcers.

Introduction: Alzheimer’s Disease (AD) is classified as progressive neurodegenerative and represents one of the main causes of dementia in the elderly. Its symptomatology is characterized by loss of memory, neuronal destruction and reduction of brain volume. The literature reports a series of metabolic and immunological changes that contribute to the progression of the disease. Objective: To carry out a review of the literature on metabolic and immunological modifications present in Alzheimer’s Disease. Methodology: 34 articles, published between 2008 and 2017, were pre-selected in the SciELO database, using the descriptors: Inflammation + Alzheimer’s Disease; Hypotheses + Alzheimer + Etiology; Alzheimer’s Disease + Lymphocytes; Metabolism + Alzheimer’s. After analysis of the abstracts, 4 articles were analyzed in full. Results and Discussion: The following metabolic alterations were observed in patients with AD: folic acid reduction, arginine reduction and increase of calcium influx to cell. Serum folic acid concentration is reduced in AD patients compared to healthy elderly individuals and has an inverse relationship with the amino acid homocysteine, which can cause apoptosis and increased oxidative stress, leading to cognitive damages that characterize the progression of the disease. Changes in NMDA receptors have also been observed, so glutamate is not reuptake and accumulates in the extracellular environment causing toxicity. In addition, as a consequence, there is a high influx of calcium leading to toxicity and apoptosis of neuronal cells. In relation to the immunological alterations, were found reduction of lymphocytes, increase of interleukin and increase of microglia, which in high quantity produce neurotoxins that contribute to the neuropathogenic mechanism of AD. In relation to the level of arginine, the amino acid involved with the energetic process, it was observed that some cells of the immune system consume it abnormally, resulting in the energy decrease and slowness of metabolism, characteristic of AD. Conclusion: Metabolic and…

Introduction: Lectins are a class of proteins extracted from the seeds of Canavalia brasiliensis (Lectin ConBr). Its anti-neoplastic activity has been studied in experimental models. Aim: To evaluate the neuropsychomotor effect of Lectin ConBr in vivo in murine. Methods: Thirty Swiss mice were divided into three groups: GCcontrol (n = 10) administered saline solution; G1experimental (n = 10) 50mg/kg and G2experimental (n = 10) 300mg/kg of Lectin ConBr. The neuropsychomotor analysis was performed by The Open Field Test, 4 and 24 hours after treatment. The statistic was performed by Student’s t-test. Results and Discussion: In the CG, the results obtained after 4h were: ambulation 55.4 ± 16.8; self-cleaning 4.8 ± 1.3; lifting 21.5 ± 3.41 and defecation 0.6 ± 0.5. G1: ambulation 43.4 ± 29.11; self-cleaning 3.4 ± 1.6; lifting 8.0 ± 8.1 and defecation 0.2 ± 0.44. G2: ambulation 63.0 ± 14.58; self-cleaning 1.0 ± 0.7; lifting 12.8 ± 3.1 and defecation 0.2 ± 0.44. The results obtained after 24 hours were: GC: ambulation 62.2 ± 27.9; self-cleaning 2.6 ± 1.5; lifting 15.3 ± 5.8 and defecation 1.4 ± 0.5. G1: ambulation 32.0 ± 15.7; self-cleaning 1.8 ± 1.7; lifting 6.0 ± 6.0; defecation 0.6 ± 0.5. G2: ambulation 62.0 ± 30.1; self-cleaning 0.6 ± 0.5; lifting 16.8 ± 7.3 and defecation 0.4 ± 0.5*. ConBr did not alter the spontaneous movement of the mice after 4 hours, however, the self-cleaning act and the total number of lifting in the treated groups decreased. After 24 hours, it was observed that self-cleaning decreased at the dose of 300mg/kg, lifting was decreased at a dose of 50mg/kg and the number of fecal cakes was decreased at all doses, suggesting anxiolytic action without motor impairment. Conclusion: The results indicate an anxiolytic effect of ConBr on treated animals when compared to the control…

Introduction: Cervical cancer is considered a serious public health problem, especially in underdeveloped countries. The causal factor of the disease is infection of the vaginal mucosa by human papillomavirus (HPV). HPV consists of more than 130 genotypes, the genotypes of higher prevalence in histopathological diagnoses are subtypes 16 and 18. Currently diagnostic techniques such as pap smears and HPV test do not cover viral subtypes, important for identifying the presence of the high-risk genotypes in the sample, stopping the progression to cervical cancer. Genotyping consists of the secondary screening method for identification of viral subtypes, bringing promising prospects for the early diagnosis of the disease. Objective: To evaluate genotyping as an alternative for the early identification of the high risk HPV genotype as a possibility for the prevention of cervical cancer. Methodology: Electronic data platforms (MEDLINE, PubMed and Scopus) were consulted from 2012 to 2016, using the descriptors: “cervical cancer”, “HPV” and “genotyping”. Results and Discussion: With the applications of genotyping, it is possible to detect elements that indicate the presence of high-risk HPV subtypes in the positive samples in the initial screening techniques. Through the detection of the p16 and ki-67 proteins, which are expressed in the stages of the cell cycle, the decrease of these biomarkers indicates a deregulation in the cellular proliferation, indicating the oncogenic manifestation. The advancement of technologies has contributed to add improvements to screening programs and thus make them more effective in detecting women who have a greater potential for progression to cervical cancer. Conclusion: Although several techniques for identifying cancer caused by HPV have already been applied, they do not yet have coverage for a quick and accurate diagnosis of the viral genotype.