International Congress 2018

Introduction: Liver transplantation is a complex procedure chosen for the treatment of patients with liver diseases that result in organ failure. The Nurse integrates a transplant team where activities such as planning, coordinating and supervising are developed according to the Federal Nursing Council. Objective: Describe the practice of the nursing students in the organ harvesting process for liver transplantation. Methodology: This is an experience report of a descriptive nature, experienced by nursing students in the Liver Transplants Academic League of Pernambuco during the first semester of 2017. Results and Discussion: The nursing students are scheduled to work together with the nurses of the team in the organ harvesting as follows: a pair of students is on notice until a donation is confirmed in a hospital of Recife. Thereafter, the couple and the nurse go to the hospital where the transplant will be done to collect all the necessary materials during the organ harvesting surgery. After that, they go to the hospital where the donor is to prepare and organize the operating room. During excision, 4 liters of organ preservation solution are used in a procedure called in situ perfusion. At the end of surgery, when the organ is removed, another 1 liter of solution is used in the stage called ex situ perfusion. After the organ is perfused, it is stored in sterile plastic bags with ice and saline solution and finally placed in a thermal box covered with ice so that it is preserved until it reaches the hospital where the transplant will finally be done. Conclusion: Through the insertion in the academic league, students have the opportunity to expand their knowledge and learn in practice, how the donation and the organ harvesting for transplantation work.

Introduction: Nowadays, mental health work is understood through team work and aimed at the collective with the perspective of articulating and adding knowledge. In this sense, the broadening of the professionals perspective and training is essential to enhance care, especially in the issues of coping with self-inflicted violence, especially the suicidal behavior responsible for the death of approximately 800,000 people per year. Objective: to report the experience of training in the subject of suicide prevention for health professionals in the state of Pernambuco. Methodology: The proposal was developed in September 2017 in the training format, offered by a group of researchers from the Federal University of Pernambuco. The target audience was the professionals who work at the various levels of mental healthcare in the State of Pernambuco. The training was structured in three thematic axes: 1- Basic concepts; 2- Risk factors and profiles; 3- Management and prevention. Results and Discussion: The vast majority of professionals approved the proposal, in its 90,3% format, thematic 95,0% and content 97,0%. In total 99,0% considered the action to be important for their professional training and ensures afety regarding retention and apprehension of the subject, and can contribute more effectively to the issue of suicidal behavior. It can be considered that the experience contributed significantly to teaching and scientific research through the articulation of university researchers and professionals in mental healthcare, being considered as an action of permanent education and training, indispensable tools in the content of public health. Conclusion: It is considered that the action was successful in order to enable the comprehension and broadened view of the professionals of the multi professional team to promote the integral care of the subject who suffers, enabling the listening and support even the engagement in a specialized network.

Introduction: The psychologist’s intervention in palliative care has widened glances on the dignity of the patient with chronic-degenerative diseases. In this way we perceive the relevance of the psychologist’s possibilities in acting together with the patient-family-health team. The aim of this study is to discuss the role of the psychologist in the context of palliative care in patients with cancer, relatives and staff. The methodology used was a bibliographic review. About the results found, points to the increasing number of people with chronic-degenerative diseases having cancers as one of the leading causes of death in the world. This fact emerges the need to include palliative care in the ongoing training of psychologists. In oncology, the recurrence of palliative chemotherapy, where patients adhere to relieve symptoms in their final months, promise to increase the life span and may also slow down the pain. But prolonging the life span is always the best option? In this scenario, the hospital psychologist, along with the team and their families, is responsible for promoting respect for the patient’s rights to make their own choices, presenting clear data about the disease and its evolution and respecting its limits of understanding and emotional tolerance. In addition to also acting on the quality of life of patients with end-stage cancer, as a facilitating agent in coping with stressful, sometimes aversive, events related to the treatment process, among them: aggressive pharmacological therapy and its side effects. The psycho oncology concludes that palliativeness deals with the acceptance of the human condition in the face of finitude, presenting to the patient outside the possibilities of healing, to his relatives and friends, the necessary conditions for the understanding of his finitude, since, in this perspective, is a disease to be cured, but the end of the life cycle. Therefore, the study made…

Introduction: Parkinson’s disease has a chronic and neurodegenerative evolution. With population aging, its incidence and prevalence increase. Its clinical features consist mainly of tremor, stiffness and bradykinesia; however, it is increasingly evident that non-motor symptoms, even if they are outside the diagnostic criteria, may be more disabling than motor manifestations. Studies indicate that visual hallucinations may be a prodromal symptom for cognitive impairment in these patients. Objective: To verify the association between visual hallucinations as a predictive factor for the development of cognitive alterations in Parkinson’s disease. Methodology: A search was performed on the PubMed and BVS databases, using the descriptors “Hallucinations”, “Cognition” and “Parkinson’s disease”. The inclusion criteria were: articles published between 2013 and 2017, in English and that fit the theme chosen. Review articles and on animals were excluded. Results and Discussion: From the 54 articles located, only 15 were in the focus of this review. Although visual hallucinations occur in about a quarter of patients with Parkinson’s disease, they are not well recognized in medical practice, even though they are associated with the onset of psychosis, motor signals and more severe depression, and are an important risk factor for the development of dementia in Parkinson’s Disease. Therefore, the early recognition of visual hallucinations and cognitive changes in this disease would allow directed intervention in the early stages and a better prognosis. Conclusion: The studies point to the need of the identification of visual hallucinations and cognitive impairment in Parkinson’s disease who have not been properly recognized. This perception may contribute to an earlier, holistic and integrated care, also considering these non-motor symptoms in the treatment, providing quality of life for patients, their families, caregivers and reducing the need for institutionalization.

Introduction: Chronic Non-Progressive Encephalopathy, commonly known as cerebral palsy, is one of the most common childhood disorders, arising in early childhood. It is characterized by being a persistent disorder in several structures and functions (of tonus, posture and movement), causing a series of limitations regarding the accomplishment of functional activities. Objective: To report the experience of the practical activities of the compulsory supervised internship of speech therapy course in relation to the patient with Chronic Non-Progressive Encephalopathy. Methodology: During the supervised stage, actions were carried out for speech-language intervention in patients with CNPE, where was carried out anamnesis, evaluation, speech-language therapy, guidelines and, when necessary, the patients were referred to the other specialties according to the needs observed. During the speech-language evaluation process, the analysis of the development of language aspects, communicative skills, evaluation of the functions and structures of the stomatoglossognatic system and auditory perception through musical resources and sound instruments were made. The intervention occurred on a weekly basis, with half an hour of duration, being stimulated the aspects of the language and worked the orofacial myofunctional structures. Results and Discussion: It was possible to observe that all the patients had enough communicative intention, development of language appropriate to the age group, however, they presented alterations in the stomatoglossognatic system with impairment of mobility, sensitivity and tonicity of the phonoarticulatory organs, emphasizing: orofacial hypotonia, with interference of the musculature for the complete absence of lip seal, protrusion and lateralization of the tongue and phonemic articulation. Rehabilitation for speech-language disorders in individuals with Chronic Non-Progressive Encephalopathy will depend on the type and degree of overall motor impairment, comprehension and language aspects of each patient. Conclusion: It is necessary the speech-language and multidisciplinary intervention in an early, effective and humanized way, favoring the development of these skills and seeking to…

Introduction: Due to the increased aging, growing chronic and degenerative diseases. Parkinson’s disease (PD) is a chronic neurodegenerative disorder, which is caused by the degeneration of substantia nigra cells. The main signs of PD are tremor at rest, muscle rigidity, bradykinesia, idle and commitment in postural control and balance. Being frequent the use of technology applied to rehabilitation, one of them is virtual reality (VR), which stimulates the movement of the whole body by means of computer-based games, in order to recreate and enhance the sense of reality to the player with interactive games. The RV not immersive, the player interacts with the game, but it has the feeling of being in the real world by using, for example, joystick or common screen uses more interfaces for Nitendo Wii or Microsoft KinectTM, to assist in the rehabilitation of elderly people with PD. Objectives: To conduct a literature review on the effects of RV in the rehabilitation of patients with Parkinson’s disease. Methods: A literature review was performed from items available in Scielo databases, PubMed, Lilacs, Medline in August 2017, selecting articles published from 2012 to 2017. Results and Discussion: Initially found 85 studies with the theme proposal, among them, 77 were excluded according to the exclusion criteria. Selecting articles 8, 4 case studies and literature reviews 4. Results report that RV helps increase the speed and movement time, gait, balance, postural control and reduction of falls. Conclusion: RV helps enhance the physiotherapeutic treatment both in motor control, functionality, balance, and cognitive ability on account of the treatment be playful and need concentration, but still needs more scientific studies with methodological qualities to confirm the results of the RV in rehabilitation in Parkinson’s disease.

Introduction:Acute kidney injury (AKI) may predispose the onset of chronic kidney disease (CKD) and hypertension through changes in renal NADPH oxidase and renal fibrosis. Objectives: To investigate, in rats, whether AKI induces later renal fibrosis through NADPH oxidase activation. Methodology: This protocol was approved by the Committee of Ethics in Animal Experimentation of UFPE (nº 23076.060473/2014-91). Male Wistar rats (120 days-old; n=8) were submitted to AKI through bilateral renal ischemia-reperfusion injury (IR; 45 min ischemia followed by 30 days of reperfusion). One group (n=8) was submitted to IR in the presence of oral apocynin administration (100 mg/kg) 24 hours before and after IR, to inhibit NADPH oxidase activity, while other (n=8), received daily oral treatment with apocynin (100 mg/kg) 24 hours after reperfusion until the end of experiment. These groups were compared to a control group submitted to simulation of IR procedure. Thirty days after reperfusion, it was evaluated creatinine clearance (ClCreat) and systolic blood pressure (SBP), as well as kidney collection, to evaluate lipid peroxidation, NADPH oxidase activity and collagen deposition. Statistical analysis was performed using one-way ANOVA followed by Newman-Keuls test (P

Introdution: Usnic acid, a hydrophobic lichen metabolite, has been highlighted in the literature with several biological activities, such as: anti-inflammatory, analgesic, antimicrobial, antiviral, antiparasitic, gastroprotective, antitumor and cicatrizant. Despite the fact that the usnic acid presents several biological activities, its use as a therapeutic agent has not yet been possible due to its inconvenient physico-chemical properties, such as low solubility, toxicity and difficult interaction with biological barriers. Thus, the incorporation of the usnic acid (UA) in controlled release systems, such as microparticles, can reduce the toxicity of this compound and make it a viable alternative for therapeutic application. Objective: To analyze the properties of poly-ε-caprolactone microspheres incorporated with usnic acid on the histomorphometry of the renal corpuscles of Swiss mice submitted to the acute toxicity test. Methodology: The groups treated with vehicle (0.9% NaCl and 5% cremophor), usnic acid (2000, 300 and 50 mg/kg) and microspheres incorporated with usnic acid (UA-Micro) in the dose of 2000 mg/kg were subjected to the acute toxicity test according to Organisation for Economic Co-operation and Development (OECD – Guideline, 423). Fragments of renal tissue were removed for preparation of histological slides, subsequently stained with Hematoxylin and Eosin. The morphometric analysis of renal capsule diameters was performed using the IMAGE software from the photomicrographs (final magnification 790 μm). Statistical analysis of the renal capsule diameters was performed using Variance (ANOVA), followed by the Tukey test. Results and Discussion: Treatment with UA-Micro (2000 mg/kg) and UA (50 mg/kg) did not show histomorphometric changes in the glomerular capsule, but treatments with UA (2000 and 300 mg/kg) caused histomorphometric changes in the glomerular capsule (**** p

Introduction: Phenylketonuria is a hereditary disease characterized by the absence of the enzyme phenylalanine hydroxylase, which converts the amino acid phenylalanine to tyrosine. Phenylalanine, accumulates in the body, and confers toxicity mainly to the central nervous system. Diagnosis, as well as early treatment is essential for the child to develop normally. Objective: To describe the diagnosis and treatment of phenylketonuric patients. Methodology: A review of the literature was conducted through articles published in journals indexed in the Scielo and PubMed databases, In the Portuguese language, in the last 8 years, using the descriptors: diagnosis, phenylketonuria, treatment. Results and Discussion: The diagnosis of phenylketonuria is made through neonatal screening, foot test, where the concentrations of phenylalanine and tyrosine are identified. When phenylalanine levels are elevated and tyrosine levels are low, the diagnosis of the disease is proven. When performed early, the diagnosis and consequently the start of treatment, can prevent the irreversible neurological damage that high doses of phenylalanine cause in patients. The recommended treatment is still a restricted diet of phenylalanine, with the use of a diet with low intake of phenylalanine in the child’s diet, in the first month of life, can significantly prevent mental retardation. That is, a feed free of foods containing phenylalanine protein, such as food of animal origin (meats and their derivatives) vegetable origin (legumes and oilseeds) and sweeteners and / or foods containing aspartame. The greatest difficulty in the elaboration of these diets is to meet the nutritional needs of the patient so that it has its full development. Conclusion: Early diagnosis along with adequate treatment will allow the patient with phenylketonuria to develop and grow optimally. The monitoring of the nutritionist and the physician, is of paramount importance to minimize the adverse effects resulting from the accumulation of phenylalanine.

Background: Diabetes mellitus is a clinical syndrome characterized by hyperglycemia due to a deficiency or decrease of insulin, causing metabolic disorders of carbohydrates, water, electrolytes, lipids and proteins, this affects the pancreatic function until the rupture of insulin production. This disease may manifest itself in pregnancy (Gestational Diabetes Mellitus or GDM), when a degree of glucose tolerance is observed, bringing various risks to the mother and fetus. Aim: The aim of this study was to identify the main causes of Gestacional diabetes, analyzing the complications of GDM, and the main treatments. Methods: Review of published researches from 2010 to 2017 in the Google Scholar, Scielo and Bireme databases, using the descriptors Diabetes Mellitus and Gestational Diabetes Mellitus. Results: The causes of gestational diabetes mellitus are mainly related to weight gain, family history, and occurrence of the disease during another pregnancy and it may cause damage such as premature rupture of membranes, pre-eclampsia, premature birth and hypertension. The fetus can develop hypocligemia, macrosomia, respiratory disorders, electrolyte disturbances, cardiomyopathy, neonatal asphyxia, among other complications. In the most recommended treatments, it is important to improve the lifestyle of the pregnant woman, and the drug treatment with oral anti-hyperglycemic agents as metformin and glibenclamide, or Insulin therapy, and according to the studies, the most efficient are the insulins glargine, aspart, regular and lispro. Discussion: The change in quality of life refers to the adoption of balanced diet and physical activity being the first treatment option for GDM, if this does not help controlling the glycemic levels, the drug therapy must be used. Conclusion: It is of great importance to be aware of the risks caused in gestational diabetes during the planning of a pregnancy, with emphasis on changing habits of life and weight control and monitoring of health professionals, preventing this and other diseases.