International Journal of Bioscience and Medicine

Review Article of International Journal of Bioscience and Medicine Aromatherapy: Prophylactic and Therapeutic Approach to Diseases of the Respiratory System Alan Lucena de Vasconcelos1, De Vasconcelos, A.L1; Alex Lucena de Vasconcelos2 MSc. Pharmacist of the Clinical Research Group at Instituto de Ensino e Pesquisa Alberto Ferreira da Costa. ZIP Code: 52.010-075 - Recife, PE - Brazil1. PhD Pharmacist Professor of the Pharmacy Department at the Pernambuco Health College - FPS2 Infectious diseases are a significant public health challenge due to the increasing recognition of new infectious agents and the resurgence of infections until recently controlled. These infectious illnesses constitute many hospital admissions, mainly respiratory focus, which requires high-cost therapy. One of the strategies to prevent injuries leading to hospitalization is reducing the body’s inflammatory response. Thus, aromatherapy seems to be a useful adjuvant therapeutic tool due to the essential oils’ synergistic action with proven anti-inflammatory and antimicrobial properties. Hence, this study proposes an integrated review of the literature on aromatherapy as a tool to be used in prophylaxis and therapy in respiratory system disorders. After passing the criteria of exclusion and content analysis, a set of 124 articles narrowed to 44 articles that support the anti-inflammatory properties of the sesquiterpenes, such as the farnesol. This substance treats the respiratory system and is present in Cymbopogon nardus, Cymbopogon flexuosus, and Rosa damascena. Caryophyllene and its derivatives are present in Syzygium aromaticum, Rosmarinus officinalis, and Cannabis sativa. Besides, α-bisabolol and chamazulene present in Matricaria recutita and Achillea millefolium. Other oils have antibiotic properties that act against gram-positive and gram-negative bacterias according to their constitution’s complexity and interaction with these microorganisms. In this context, some species such as Cinnamomum zeylanicum, Citrus hystrix, Cymbopogon Citratus, Eucalyptus globulus, Eucalyptus odorata, Juniperus communis, Lavandula angustifólia, Lavandula intermedia, Melaleuca leucadendra, Mentha piperita, Pinus sylvestris, Syzygium aromaticum, and ...

Review Article of International Journal of Bioscience and Medicine SIGNS OF SUCETTABILITY ASSOCIATED WITH EXTRINSIC FACTORS TO FUNGAL INFECTION BY THE GENUS SPOROTHRIX SPP. Rubens Barbosa Rezende1 *, Larissa Teodoro2 1Faculdade Santa Rita (FASAR), Conselheiro Lafaiete – MG; 2Instituto de Ciências da Saúde da Universidade Paulista (UNIP), Campinas – SP. Objective: To evaluate the susceptibility to infection by the genus sporothrix spp.; targeting patients with immunosuppression due to the use of inadequate medication, seropositive patients (carriers of Human Immunodeficiency Syndrome - HIV) and alcoholics dependents. Method: This is an integrative review of the literature available in the PUBMED database, using the descriptors: “Sporotrichosis”, “Fungi” and “Sporothrix”, duly registered in MeSH, using the boolean operator AND. A total of 128 articles were found and evaluated and, at the end, 15 were selected to compose this review. The inclusion criteria were: full articles, available free of charge, published in English between 2010 and 2020. Results: Sporotrichosis is clinically characterized in fixed cutaneous, lymphocutaneous, disseminated cutaneous and extracutaneous. Frequently the appearance of disseminated cutaneous sporotrichosis occurs especially in immunosuppressed individuals. The four cases evaluated have as etiological agent in common, the genus Sporothrix spp., distinguishing the species, the contagion, clinical aspects and their susceptibility factors. Conclusion: However, most cases of sporotrichosis are related to a dysfunction of the immune system. As well, the unusual cases characterize a challenge to reliable diagnosis and can often lead to a wrong pharmacological therapy. Keywords: Sporotrichosis, Fungi, Sporothrix ...

Research Article of International Journal of Bioscience and Medicine USE OF GLUTAMINE AS AN ADJUVING THERAPY FOR THE NUTRITIONAL AND PHYSIOLOGICAL RESTORATION OF THE BIG BURNED PATIENT Ziane da Conceição das Mercês1 *, Gabriela Andersson Antunes Buchmann2, 1Especialista em Nutrição e exercício voltado ao tratamento e prevenção de doenças, Responsável Técnica na Secretaria de Educação no Município de Aveiro, Pará; 2 Especialista em Terapia Nutricional em Cuidados Intensivos. Objective: To analyze the applicability of glutamine in the recovery of the nutritional and physiological status of burn patients. Methods: Study based on a literary review taken from reliable sources such as: The Scientific Electronic Library Online (Scielo), Pubmed, Bireme, Latin American and Caribbean Literature in Health Sciences (Lilacs), Virtual Health Library, the descriptors used were: glutamine ; nutritional therapy; burned; nutrition therapy; burned patients; glutamine, published in the last eleven years (2009-2020). Results: The research was carried out in a literary review format 30 full documents were read, 23 scientific articles were used, 3 bases of the Ministry of Health, 7 were postponed, the arguments used in the composition of the article, were the answer to the problem about applicability about the nutrient with immunomodulatory function glutamine for the recovery of the nutritional and physiological state of burn patients. Conclusion: The research argued about the use of glutamine in the treatment of large burn patients, through data obtained by literary analysis. The results obtained will contribute to the guidelines on the use of immunonutrients to improve the immune response, modulate the inflammatory response, reduce the rates of infectious complications, bringing a possible reduction in hospitalization costs. However, there is a need for further studies focused on this topic, in order to make the benefits of these immunonutrients appreciable for the scientific community, especially in terms of nutritional support more appropriate to ...

Review Article of International Journal of Bioscience and Medicine Antioxidant Activity and Hemotoxicity of Medicinal Plant of the Caatinga Domain: Amburana Cearensis (Fabaceae) João Victor de Oliveira Alves1*, Francisco Henrique da Silva1, Maria Victoria dos Santos Alves Evaristo2, Janderson Weydson Lopes Menezes da Silva3, Paloma Maria da Silva1, Larissa Gomes de Arruda1, Irivânia Fidelis da Silva Aguiar1, Saulo Almeida de Menezes1, Fálba Bernadete Ramos dos Anjos4, Márcia Vanusa da Silva1 1Biochemistry Department, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil; 2Graduated in Biological Sciences, Institute of Biological Cienicas, Campus Santo Amaro, Universidade de Pernambuco; 3Aggeu Magalhães Institute (IAM) - FIOCRUZ/PE, Brazil. 4Department of Histology and Embryology, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil Amburana cearensis is a medicinal species popularly known as “cherry” or “aroma amburana” that has wide distribution in South America, being characteristic of Seasonal Forests. It also occurs in Semideciduous Seasonal Forest, restricted to rocky or limestone outcrops; in Submontane Deciduous SubmontanaSeasonalForest; in Dense Ombrophilous Forest (Atlantic Forest) and even in caatinga/dry forest. Taking into account the growing interest in the search for agents that act in the face of oxidative stress, without causing toxic effects to biological systems, the present study aimed to investigate the phytochemical composition and evaluate the antioxidant and hemotoxic activities in vitro of the aqueous extract obtained from the shells of Amburana cearensis (EAAc). Hemaglutination wasevaluated for human erythrocytes collected from people with the presence of O+ blood. In the face of the tests, Amburana cearensis presented significant results for antioxidant activity without causing erythrocyte hemolysis, highlighting the importance of the species as a source of antioxidant agents, which are recognized for blocking the evolution and acting to combat symptoms triggered by diseases associated with oxidative stress. Keywords: Caatinga. Aqueousextract. Erythrocytes. Free radicals ...