International Journal of Case Reports


Giant gastric carcinosarcoma infiltrating the left hepatic lobe: a case report

Case Report of International Journal of Case Reports Giant gastric carcinosarcoma infiltrating the left hepatic lobe: a case report Leonardo Vincenti MD1, Cinzia Bizzoca MD1, Salvatore Fedele MD2, Anna Maria Valentini BScD3, Valeria Andriola1, Graziana Arborea MD3 1General Surgery “Ospedaliera”, Policlynics of Bari, Italy; 2Dept of General Surgery, National Institute of Gastroenterology “S. de Bellis”, Research Hospital, CastellanaGrotte (BA), Italy; 3Dept of Pathology, National Institute of Gastroenterology “S. de Bellis”, Research Hospital, Castellana Grotte (BA), Italy Gastric carcinosarcoma is a rare biphasic tumor that consists of both carcinomatous and sarcomatous components. Clinical presentation and neoplastic markers are not specific for the disease. Moreover, CT scan cannot distinguish among gastric carcinoma, sarcoma or carcinosarcoma, so it is essential to perform histopathological and immunohistochemical analysis on biopsy specimens or resected tissue to ensure a correct diagnosis. A 72-year-old woman was transferred to our Department from another hospital with a diagnosis of a bleeding tumor localized on the lesser gastric curve, infiltrating the left hepatic lobe. The mass was treated as a gastric malignant mesenchymal neoplasia (gastro-intestinal stromal tumor versus sarcoma) infiltrating the liver. Owing to the bleeding, no further invasive examinations, such as fine needle aspiration biopsy, were planned. Furthermore, no neoadjuvant chemotherapy could be administered before surgery due to persistent anaemia. The scheduled surgical procedure was an atypical gastric resection with “en bloc” hepatic resection. This operation included upper polar and lesser curve resection, with tubulization of the stomach along the greater curve, as well as left lateral hepatic sectionectomy. Histopathological examination and immunohistochemical staining confirmed the diagnosis of gastric carcinosarcoma. This is first report of gastric carcinosarcoma with local liver infiltration, treated with surgical resection. Keywords: Gastric Carcinosarcoma; Gastrectomy; Hepatic resection ...

A Case of Recurrent Facial Palsy Associated with Anti-GM2: is it anyway Guillain-barré syndrome?

Case Report of International Journal of Case Reports A Case of Recurrent Facial Palsy Associated with Anti-GM2: is it anyway Guillain-barré syndrome? Giovanni Bonaccorso Region skåne Objective: A rare case of possible hereditary predisposition to autoimmune neuropathy Background: This case report is of a patient who presented two episodes of Facial paresis in her live without ascertained apparent causes. Bell’s palsy is commonly known as peripheral idiopathic facial nerve palsy, because in the most cases the triggers remain unknown (1). Case Report: I want to present a case of a 34 year old woman who we will call A.B. and who came to us to evaluate the severity of the sequelae of a Bell´s palsy and any eventual need for cosmetic measure. But she had another Bell´s Palsy 9 years ago, so I started to investigate the most common and treatable causes of Facial paresis. I found a significate increase of anti-bodies against ganglioside GM2. When I explained to her that these anti-bodies is commonly related with several neurological diseases, she started to investigate her family history and she found that his father’s brother died of Guillain Barré syndrome about 40 years ago. Keywords: Bell´s palsy, facial, palsy, paresis, Guillain Barré syndrome, ganglioside, Antibodies, GM2 ...

Intramyocardial haemorrhage: a rare sequela of acute myopericarditis

Case Report of International Journal of Case Reports Intramyocardial haemorrhage: a rare sequela of acute myopericarditis Sahar Mohmed1, Kate Batouskaya1, Jakub Lagan2, Pei Gee Chew1,2, Dania Mohty3,4, Aleem Khand1,2,5* ¹Sahar Mohmed, MBBS, MRCP UK, (Cardiology clinical fellow, Department of Cardiology, Liverpool University Hospitals NHS Trust, Lower Lane, Liverpool L97AL, UK). ¹Kate Batouskaya (Core Medical trainee, Department of Cardiology, Liverpool Heart and Chest Hospital, Thomas Drive, Liverpool L14 3PE). ²Jakub Lagan (Cardiologist, Department of Cardiology, Liverpool Heart and Chest Hospital, Thomas Drive, Liverpool L14 3PE, UK). 1,2Pei Gee Chew, MBChB, MRCP UK, AFHEA, MD(Res) (Department of Cardiology, Liverpool University Hospitals NHS Trust, Lower Lane, Liverpool L97AL, Liverpool Heart and Chest Hospital, Thomas Drive, Liverpool L14 3PE, UK). 3,4Dania Mohty, University of Limoges, Limoges, France, King Faisal Specialist Hospital, Riyadh, Saudi Arabia). 1,2,5Aleem Khand, MBChB MRCP MD Dip Interventional  Card iologyand Cardiac MRI FESC, Cardiology Consultant, Department of Cardiology, Liverpool University Hospitals NHS Trust, Lower Lane, Liverpool L97AL, Department of Cardiology, Liverpool Heart and Chest Hospital, Thomas Drive, Liverpool L14 3PE, UK. University of Liverpool). INTRODUCTION Acute myopericarditis is an inflammatory disease of myocardium and pericardium. The disease has variable presentation ranging from mildly symptomatic cases to severe disease manifested by cardiomyopathy with associated risk of sudden cardiac death. However, the association with intramyocardial hemorrhage (IMH) has not been previously described. CASE REPORT We describe an IMH detected by cardiac magnetic resonance imaging, in a patient with classical ‘de novo’ myopericarditis. To the best of the authors’ knowledge, this has not been previously described in patients without associated haematological or connective tissue disorders. CONCLUSION The adverse prognostic signal of IMH in acute myocardial infarction may also be reflected by IMH in acute myopericarditis and lead to adverse ventricular remodeling. The pathophysiology of IMH in myopericarditis is unknown and warrants further exploration. Keywords: Intramyocardial ...

SYNGAP1 Mutation in absence Epilepsy with eyelid myoclonia: A Literature Overview and A Case Report from Qatar

Case Report of International Journal of Case Reports SYNGAP1 Mutation in absence Epilepsy with eyelid myoclonia: A Literature Overview and A Case Report from Qatar Rana AL-Shami , Sondos Altaraqji, Khalid Mohamed Pediatric Neurology Sidra Medicine Background: SYNGAP1, which encodes a RAS-GTPase-activating protein, is located on the short arm of chromosome 6.Mutations of the SYNGAP1 gene were first identified in 2009 in patients with nonsyndromic intellectual disability (ID) acquired microcephaly, and autism spectrum disorder (ASD), followed in 2013 by recognition of their important role in the developmental and epileptic encephalopathies (DEEs). Developmental delay was identified soon after birth in the majority of patients and pre-ceded seizure onset in all. Development regressed or plateaued with seizure onset were observed. Language was severely impaired together with intellectual disabilities and some other features (1, 4).Most affected individuals have de novo mutations, with truncating mutations predominating, although missense mutations, chromosomal translocations, or microdeletions disrupting SYNGAP1 are also described. (1,5). Keywords: SYNGAP1; Epilepsy, Pediatric ...

Acute cauda equina syndrome due to lumbar spinal stenosis caused by prolonged supine position during cardiac catheterization: a case report

Case Report of International Journal of Case Reports Acute cauda equina syndrome due to lumbar spinal stenosis caused by prolonged supine position during cardiac catheterization: a case report Kazuki Kobayashi, Kazuyuki Watanabe, Kinshi Kato, Michiyuki Hakozaki, Jun-ichi Handa, Hiroshi Kobayashi, Takuya Nikaido, Koji Otani, Shoji Yabuki, and Shin-ichi Konno Department of Orthopaedic Surgery, Fukushima Medical University School of Medicine, Fukushima, Japan Background: Cauda equina syndrome (CES) is a severe neurologic condition marked by progressive loss of function of the neurologic elements in the spinal canal below the termination of the spinal cord. This article reports an instructive case of CES with acute aggravation of neuropathy after catheter ablation for atrial fibrillation. Patient concerns: A 63-year-old Japanese man underwent catheter ablation for atrial fibrillation. Because he complained of severe low back pain and numbness in the posterior of both lower limbs while in the supine position, he was given analgesia with pentazocine and sedated with propofol, and the procedure continued. He was then forced to maintain lumbar extension while in the supine position for 13 hours. After the treatment, he noticed urination disor-der, numbness, and paralysis of both lower limbs. Diagnosis: Neurological findings included sensory impairment and motor deficit of L5 and below, including bowel/bladder dysfunction. Lumbar magnetic resonance imaging showed severe lumbar spinal stenosis at L4-L5. He was diagnosed with CES due to lumbar spinal stenosis. Interventions: The patient received emergency surgery for L4-L5 decompression. Decompression of the spinal canal was achieved 33 hours after the start of catheterization. Outcomes: The patient’s leg symptoms improved immediately after surgery, and he was able to walk with a walker. On postoperative day 6, the urinary catheter was removed. However, he experienced urinary retention and needed intermittent self-directed urination. Five months after surgery, he was able to urinate on his own, and completed the ...

Dr. Xiaoning Luo
Professor, Department of Otorhinolarygology-Head and Neck Surgery, Guangdong General Hospital, Guangzhou, China

Dr. N.S. NEKI
Professor & Head, Dept.of Medicine, Govt. Medical College, Amritsar, India

Dr. Jitesh K. Kar
Clinical assistant professor, Department of Internal Medicine – Neurology, University of Alabama at Birmingham, Huntsville Regional Campus

Dr. Nisar Haider Zaidi
MBBS, MS, MRCS (Glasgow), FICS, FACS. Department of surgery, King Abdulaziz University Hospital , POBox-80215 Jeddah 21589 , Saudi Arabia

Dr. Giuseppe Lanza
Consultant Neurologist and Clinical Researcher, Department of Neurology IC of the “Oasi” Institute for Research on Mental Retardation and Brain Aging

Dr. Yousif Mohamed Y. Abdallah
Professor (Assistant), Radiological Science and Medical Imaging Department, College of Applied Medical Sciences, Majmaah University, Majmaah, Saudi Arabia

Dr. Karol Szyluk
District Hospital of Orthopedics and Trauma Surgery

Dr. Mohd Normani Zakaria
Chairman / Head of Hospital Unit / Assistant Professor / Consultant Audiologist, Audiology and Speech Pathology Programme, School of Health Sciences,, Universiti Sains Malaysia 

Dr. Dennis J. Mazur
Senior Scholar, Center for Ethics in Health Care, and Professor of Medicine, Oregon Health and Science University, Portland, Oregon USA

Dr. Marcos Roberto Tovani Palone
Department of Pathology and Legal Medicine, Faculty of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil.

Dr. Begum Sertyesilisik
Assoc. Prof. at the Istanbul Technical University

Dr. Jamunarani Veeraraghavan
Baylor College of Medicine, One Baylor Plaza, Houston, Texas 

Dr. Rajinder Pal Singh Bajwa
Niagara Falls Mem Med Center, Division of Infectious Diseases, 621 Tenth Street, Niagara Falls, NY

Dr. Can SARICA
Adiyaman University School Of Medicine, Department Of Neurosurgery, Adiyaman

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1. Avinaba Mukherjee, Sourav Sikdar, Anisur Rahman Khuda-Bukhsh. Evaluation of ameliorative potential of isolated flavonol fractions from Thuja occidentalis in lung cancer cells and in Benzo(a) pyrene induced lung toxicity in mice. International Journal of Traditional and Complementary Medicine, 2016; 1(1): 0001-0013. 
2. Vikas Gupta, Parveen Bansal, Junaid Niazi, Kamlesh Kohli, Pankaj Ghaiye. Anti-anxiety Activity of Citrus paradisi var. duncan Extracts in Swiss Albino Mice-A Preclinical Study. Journal of Herbal Medicine Research, 2016; 1(1): 0001-0006.

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Aims
International Journal of Case Reports (ISSN:2572-8776; DOI:10.28933/IJCR) is a peer reviewed open access journal publishing case reports in all kinds of diseases of all medical fields. Our aim is to provide a platform for authors from all countries to encourages publication of most recent case reports in all specialties. 

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Peer Review help ensure the quality of the publications. Manuscripts of International Journal of Case Reports will be peer-reviewed by invited experts in the field. The decisions of editors will be made based on the comments of the reviewers.

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International Journal of Case Reports (ISSN:2572-8776; DOI:10.28933/IJCR) is a journal to support Open Access initiative

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Scope: (Case reports from all medical fields.)

  • Allergy and Its Subspecialties
  • Anesthesiology and Its Subspecialties
  • Physical Medicine and Rehabilitation and Its Subspecialties
  • Urology and Its Subspecialties
  • Emergency Medicine and Its Subspecialties
  • Dermatology and Its Subspecialties
  • Medical Genetics and Its Subspecialties
  • Internal Medicine and Its Subspecialties
  • Diagnostic Radiology and Its Subspecialties
  • Neurology and Its Subspecialties
  • Psychiatry and Its Subspecialties
  • Obstetrics and Gynecology and Its Subspecialties
  • Ophthalmology and Its Subspecialties
  • Surgery and Its Subspecialties
  • Pediatrics and Its Subspecialties
  • Nuclear Medicine and Its Subspecialties
  • Preventive Medicine and Its Subspecialties
  • Radiation Oncology and Its Subspecialties
  • Pathology and Its Subspecialties
  • Family Medicine and Its Subspecialties
  • Immunology and Its Subspecialties

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