International Journal of Case Reports


Pseudo-endocarditis secondary to ruptured posteromedial papillary muscle with anatomical variation: A Case Report

Case Report of International Journal of Case Reports Pseudo-endocarditis secondary to ruptured posteromedial papillary muscle with anatomical variation: A Case Report Natassja Moriarty, MBBS1*; Jonathan Moriarty, MBBS2; Nadeem Attar,MBBS3; Adrian Brodison, MB chB4 1,2Department of Medicine, Furness General Hospital. 3,4Consultant Cardiologist, Furness General Hospital. Myocardial infarction is the leading cause of papillary muscle rupture. This complication occurs in up to 5% of cases post MI and although rare, it constitutes a cardiac emergency if left untreated. On this basis, a 59-year-old male presented with low-grade fever and atypical chest pain with raised inflammatory markers and troponin levels.  He was treated for infective endocarditis after echocardiography revealed a mass on the mitral valve, which was presumed to be a mitral valve vegetation and so he completed a 6-weeks course of antibiotics followed by elective mitral valve replacement surgery. During surgery, it was discovered that there was no endocarditis. Instead an unusually small muscle head of one of the posteromedial papillary muscle groups had ruptured secondary to an inferior myocardial infarction. This ruptured muscle head was highly mobile and mimicked a mitral valve vegetation. The mitral valve was successfully repaired, and the right coronary artery grafted. He made a full recovery but developed new-onset atrial fibrillation for which he is awaiting elective cardioversion. One should have a high index of suspicion for diagnosing papillary muscle rupture as it may mimic valvular vegetation on echocardiography, especially if the papillary muscle involved is an anatomical variant. Keywords: Papillary muscle, rupture, endocarditis, mitral valve ...

Secondary hyperparathyroidism and symptomatic hypercalcemia: overlooked complications of chronic liver disease

Case Report of International Journal of Case Reports Secondary hyperparathyroidism and symptomatic hypercalcemia: overlooked complications of chronic liver disease Hoilat JN1*, Hoilat GJ2, Kadan S3, Emanuele MA1 1Loyola University Medical Center, 2SUNY upstate medical center, 3Alfaisal University college of medicine A 71-year-old female with biopsy-proven liver cirrhosis was brought to the ER due to confusion for 5 days. She was diagnosed with acute decompensated liver disease and hepatic encephalopathy. Investigations also revealed PTH-dependent hypercalcemia. Both of these entities could be causing her symptoms. Neck ultrasound did not reveal any parathyroid lesions. Alteration in mental status persisted even after the management and resolution of hepatic encephalopathy. Symptomatic resolution occurred after normalization of her calcium levels which required normal saline, cinacalcet as well as calcitonin over the course of 7 days. Hypercalcemia secondary to chronic liver disease should be considered in the differential diagnosis of patients with liver cirrhosis presenting with an altered mental status. Hypercalcemia of chronic liver disease is not always transient and managed with normal saline as previously reported; It could necessitate more aggressive therapy with calcitonin and cinacalcet as reported in this case. Keywords: Chronic liver disease; Case report ...

Miller Fisher syndrome associated with respiratory failure

Case Report of International Journal of Case Reports Miller Fisher syndrome associated with respiratory failure Frentescu Alexandra1*, Feys Odile2, Mangion Jean-Paul3, Osseman Michel2, Horlait Geoffrey1 1Intensive Care Unit, Catholic University of Louvain, Belgium. 2Neurology Deparment, Catholic University of Louvain, CHU UCL Namur, Avenue du Docteur G. Therasse 1, 5530 Yvoir, Belgium. 3Emergency Department, Catholic University of Louvain, CHU UCL Namur, Avenue du Docteur G. Therasse 1, 5530 Yvoir, Belgium. Miller Fischer syndrome (MFS) is a rare clinical variant of Guillain-Barre syndrome. The diagnosis suspected primarily on clinical trial of areflexia, ophtalmoplegia and ataxia, is confirmed by the mandatory presence of antiganglioside antibodies (anti GQ1b). An acute onset is typical of MFS, beginning with neurological symptoms following a respiratory or digestive infectious illness. The therapeutic options are either the plasmapheresis or the administration of intravenous immunoglobulin (IVIG). Although rare, in certain cases the patients present with respiratory symptoms needing intensive care. We report the case report of a patient which presented with the classical triad of MFS but also with rapid progressive respiratory failure due to bilateral vocal cords palsy and general muscle weakness. He needed respiratory mechanical support. The patient received a treatment by IVIG without any improvement in symptomatology. Eventually he completely recovered and he was discharged from the hospital 3 month later. Keywords: Miller Fisher syndrome; Atypical; Dysphonia; Respiratory failure ...

Tuberculosis Mimicking a Testicular Tumor

Case Report of International Journal of Case Reports TUBERCULOSIS MIMICKING A TESTICULAR TUMOR Menaka Thilakarathna1*, Sasanka Wijayawardhane1, Aflah Sadikeen1, Amitha Fernando1 1National Hospital of Sri Lanka. Genitourinary tuberculosis is a challenging clinical entity which can affect the entire male genital tract. Seventy-five- year old male presented with a testicular lump masquerading a testicular malignancy. Histological and microbiological examination of testicular biopsy specimens established the diagnosis of tuberculosis. Isolated testicular tuberculosis is rarely reported. High degree of clinical suspicion and histological sampling are paramount important in the process of diagnostic evaluation. Keywords: Extra pulmonary tuberculosis; Testicular tuberculosis ...

Conditional Dysosmia: a Very Unpleasant Symptom Causing Severe Anorexia and Breathing Problems in Covid-19: a Case Report

Case Report of International Journal of Case Reports Conditional Dysosmia: a Very Unpleasant Symptom Causing Severe Anorexia and Breathing Problems in Covid-19: a Case Report Abdulmohsin Younus Saleem1 and Abdul-Wahab Al-Allaf2* 1Early detection childhood disabilities centre, Otolaryngology Department, Duhok, Iraq. 2Rheumatology Section, Department of Rheumatology, Hamad Medical Institute, Doha, Qatar. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a new coronavirus that is highly contagious and responsible for the ongoing pandemic disease; coronavirus disease (COVID-19). The disease was first identified in December 2019, and the World Health Organization declared the pandemic on the 11th of March 2020. Although individuals infected with SARS-CoV-2 may be asymptomatic, the disease can present as an upper respiratory tract illness. In the majority of the cases, it is of a mild type, however, some patients experience severe viral pneumonia that leads to respiratory failure, and, in some cases to death. A COVID-19 diagnosis is confirmed by viral RNA detection in nasopharyngeal swab specimens; nonetheless, in some countries, COVID-19 tests are not available for screening and are only used to diagnose severe cases. Since 31 December 2019 and as of 17 October 2020 and in accordance with the applied case definitions and testing strategies in the affected countries 39 400 032 cases of COVID-19 have been reported, including 1 105 353 deaths [1]. The main way to control the spread of COVID-19 is to prevent human-to-human transmission, which can be achieved through a combination of public health measures, including the rapid identification and isolation of infected people [1]. Diagnostic suspicion is based on nonspecific symptoms, such as fever, odynophagia, head-  ache, and dry cough which are present in almost all acute respiratory virus cases [2]. Anosmia, which may be associated with the loss of taste, has been initially observed in European cases and seems to be ...

Dr. Xiaoning Luo
Professor, Department of Otorhinolarygology-Head and Neck Surgery, Guangdong General Hospital, Guangzhou, China

Dr. N.S. NEKI
Professor & Head, Dept.of Medicine, Govt. Medical College, Amritsar, India

Dr. Jitesh K. Kar
Clinical assistant professor, Department of Internal Medicine – Neurology, University of Alabama at Birmingham, Huntsville Regional Campus

Dr. Nisar Haider Zaidi
MBBS, MS, MRCS (Glasgow), FICS, FACS. Department of surgery, King Abdulaziz University Hospital , POBox-80215 Jeddah 21589 , Saudi Arabia

Dr. Giuseppe Lanza
Consultant Neurologist and Clinical Researcher, Department of Neurology IC of the “Oasi” Institute for Research on Mental Retardation and Brain Aging

Dr. Yousif Mohamed Y. Abdallah
Professor (Assistant), Radiological Science and Medical Imaging Department, College of Applied Medical Sciences, Majmaah University, Majmaah, Saudi Arabia

Dr. Karol Szyluk
District Hospital of Orthopedics and Trauma Surgery

Dr. Mohd Normani Zakaria
Chairman / Head of Hospital Unit / Assistant Professor / Consultant Audiologist, Audiology and Speech Pathology Programme, School of Health Sciences,, Universiti Sains Malaysia 

Dr. Dennis J. Mazur
Senior Scholar, Center for Ethics in Health Care, and Professor of Medicine, Oregon Health and Science University, Portland, Oregon USA

Dr. Marcos Roberto Tovani Palone
Department of Pathology and Legal Medicine, Faculty of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil.

Dr. Begum Sertyesilisik
Assoc. Prof. at the Istanbul Technical University

Dr. Jamunarani Veeraraghavan
Baylor College of Medicine, One Baylor Plaza, Houston, Texas 

Dr. Rajinder Pal Singh Bajwa
Niagara Falls Mem Med Center, Division of Infectious Diseases, 621 Tenth Street, Niagara Falls, NY

Dr. Can SARICA
Adiyaman University School Of Medicine, Department Of Neurosurgery, Adiyaman

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1. Avinaba Mukherjee, Sourav Sikdar, Anisur Rahman Khuda-Bukhsh. Evaluation of ameliorative potential of isolated flavonol fractions from Thuja occidentalis in lung cancer cells and in Benzo(a) pyrene induced lung toxicity in mice. International Journal of Traditional and Complementary Medicine, 2016; 1(1): 0001-0013. 
2. Vikas Gupta, Parveen Bansal, Junaid Niazi, Kamlesh Kohli, Pankaj Ghaiye. Anti-anxiety Activity of Citrus paradisi var. duncan Extracts in Swiss Albino Mice-A Preclinical Study. Journal of Herbal Medicine Research, 2016; 1(1): 0001-0006.

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Aims
International Journal of Case Reports (ISSN:2572-8776; DOI:10.28933/IJCR) is a peer reviewed open access journal publishing case reports in all kinds of diseases of all medical fields. Our aim is to provide a platform for authors from all countries to encourages publication of most recent case reports in all specialties. 

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Peer Review help ensure the quality of the publications. Manuscripts of International Journal of Case Reports will be peer-reviewed by invited experts in the field. The decisions of editors will be made based on the comments of the reviewers.

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International Journal of Case Reports (ISSN:2572-8776; DOI:10.28933/IJCR) is a journal to support Open Access initiative

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Scope: (Case reports from all medical fields.)

  • Allergy and Its Subspecialties
  • Anesthesiology and Its Subspecialties
  • Physical Medicine and Rehabilitation and Its Subspecialties
  • Urology and Its Subspecialties
  • Emergency Medicine and Its Subspecialties
  • Dermatology and Its Subspecialties
  • Medical Genetics and Its Subspecialties
  • Internal Medicine and Its Subspecialties
  • Diagnostic Radiology and Its Subspecialties
  • Neurology and Its Subspecialties
  • Psychiatry and Its Subspecialties
  • Obstetrics and Gynecology and Its Subspecialties
  • Ophthalmology and Its Subspecialties
  • Surgery and Its Subspecialties
  • Pediatrics and Its Subspecialties
  • Nuclear Medicine and Its Subspecialties
  • Preventive Medicine and Its Subspecialties
  • Radiation Oncology and Its Subspecialties
  • Pathology and Its Subspecialties
  • Family Medicine and Its Subspecialties
  • Immunology and Its Subspecialties

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