International Journal of Case Reports


Psychosis Due to Hypothyroidism: Are Antipsychotics Indicated?

Case Report of International Journal of Case Reports Psychosis Due to Hypothyroidism: Are Antipsychotics Indicated? Deborah L. Sanchez, M.D. 1,2, Adam J. Fusick, M.D2, William B. Hudson, M.D.2, Theresa A. Schwitalla,M.D.2, Maria C. Catalano,D.O.2,3, Susan K. Schultz, M.D.1,2,4, Glenn Catalano, M.D. 1,2 1Mental Health and Behavioral Sciences Service, James A. Haley Veterans Hospital, Tampa, Florida; 2Department of Psychiatry and Behavioral Neurosciences, University of South Florida Morsani College of Medicine, Tampa, Florida; 3Ambulatory Care Service, James A. Haley Veterans Hospital, Tampa, Florida; 4Department of Psychiatry, University of Iowa Carver College of Medicine Objective: To present a case of thyroid-related psychosis and review the literature to assess evidence regarding the use of antipsychotic medications in patients who develop this condition. Data Sources: The OVID database was utilized to search for the terms “myxedema madness” and the combination of the terms “psychosis” and “thyroid.” The database was searched from 1946 until July 2018 and was limited to English language articles. Study Selection: A total of 25 articles were included in this study. These included 27 distinct case reports. Data Extraction: The abstracts of identified articles were reviewed. If an abstract was unavailable or inconclusive, the full article was reviewed. If there was no case report, or if the case was not clearly related to hypothyroidism, it was excluded. Authors assessed and identified cases included. Studies were excluded if recovery time was unreported; if cases included patients with pre-existing, chronic mental illness or intellectual disability, or if thyroid replacement medication was not initially administered. Results: Data suggested that there may be no benefit to treating thyroid-related psychosis with scheduled dosing of antipsychotics in addition to thyroid replacement. The review also suggested that male patients with thyroid-related psychosis seemed to respond more rapidly to thyroid replacement than female patients. Conclusions: Scheduled dose antipsychotic therapy was not ...

Levothyroxine malabsorption induced by gastroparesis in type one diabetic patient: effect of intravenous levothyroxine therapy case report

Case Report of International Journal of Case Reports Levothyroxine malabsorption induced by gastroparesis in type one diabetic patient: effect of intravenous levothyroxine therapy case report Homaid Alsahafi, Bandar Damanhori, Faisal AL Malky, Ashjan Alrogi, Khulood Alkhuzaie Department of Endocrinology & Diabetology, Hera General Hospital, Makkah, Saudi Arabia 19 year old female known case of primary hypothyroidism on levothyroxine replacement, type one diabetes on insulin pump with good glycemic control and stable thyroid function, developed diabetic gastroparesis with worsening response to oral levothyroxine therapy. Her symptoms of hypothyroidism and her thyroid function improved dramatically by intravenous levothyroxine three times weekly for 4 weeks then she restarted on her usual dose of oral levothyroxine. Intravenous levothyroxine three times weekly for 4 weeks followed by oral levothyroxine therapy maintained her euthyroid, improved hypothyroidism and gastroparesis symptoms till the date of editing of this report (more than 15 months.). Keywords: Levothyroxine malabsorption, gastroparesis,  type one diabetic patient, intravenous levothyroxine therapy, case report ...

Foreign Body Aspiration in Adult, What Would You Expect? Case Report

Case Report of International Journal of Case Reports Foreign Body Aspiration in Adult, What Would You Expect? Case Report Zeyad  Faoor  Alrais1,  Mohamed Ibrahim  Shoaib1, Hesham  Mohamed ElKholy1, Asad  Alsabbah2 1Department of Intensive Care Medicine, Rashid Hospital, Dubai Health Authority, Dubai, United Arab Emirates. 2Mediclinic City Hospital , Dubai, United Arab Emirates. Foreign body (FB) aspiration is an uncommon but potentially life-threatening event, while the majority of accidental aspiration events occur in children, adults represent up to 25% of cases. When the diagnosis is not established immediately, retained FBs may lead to recurrent pneumonias, bronchiectasis, recurrent hemoptysis, pneumothorax, lung abscesses, pneumo-mediastinum, or other complications. Extraction of aspirated FBs should be undertaken as soon as possible to alleviate acute symptoms and prevent long term complications. FB aspiration is slightly more common in males. The vast majority of adult patients with FB aspiration have obvious risk factors for aspiration including neurological deficits with swallowing difficulties or altered mental status, neuromuscular disease, intoxication, or have an iatrogenic cause. Still, 10% of adult patients with FB aspiration have no known risk factors. Our case is 35 y old male patient who was brought to Accident and Emergency department after being found unresponsive in the street, on arrival to hospital his GCS was 9/15 with pin points pupils , spontaneous breathing and hemodynamic stable . CT brain was unremarkable Patient failed to respond to repeated doses of naloxone and his GCS dropped with episode of apnea so was intubated and mechanically ventilated. Follow up chest x-ray show opacification of the right lung, and ABG reveled hypoxia with respiratory acidosis in spite high ventilator settings, So CT chest was the best option which reveled bronchial obstruction mostly due to foreign body. Urgent bronchoscopy was done and unexpectedly obstruction was due to chewing gum pieces, aspiration of four ...

Transfer Factor Revisited: Treatment of Candida Prosthetic Valve Endocarditis

Case Report of International Journal of Case Reports Transfer Factor Revisited: Treatment of Candida Prosthetic Valve Endocarditis J. Kelly Smith, MD, FACP1,2* 1Department of Academic Affairs, James H. Quillen College of Medicine, East Tennessee State University, USA; 2Department of Biomedical Sciences, James H. Quillen College of Medicine, East Tennessee State University, USA Candida prosthetic valve endocarditis (CPVE) is most commonly seen in persons who inject drugs intravenously or have indwelling catheters, pacemakers, or prosthetic joints that can serve as a nidus for candida suprainfection and seed the valve. Current treatment guidelines for CPVE include valve replacement and long-term antifungal therapy with intravenously administered Amphotericin B and parenteral or oral therapy with 5-fluorocytosine. Despite treatment, CPVE is characterized by a high recurrence rate (up to 36%) and a 5-year survival of less than 50%. I review my past experience in treating recalcitrant CPVE with transfer factor (TF) immunotherapy and conclude that TF can be a valuable adjuvant in the treatment of CPVE that does not respond to conventional interventions. Keywords: Transfer factor, dialyzable leukocyte extract, DLE, candida, prosthetic valve endocarditis, migration inhibition factor, MIF, monocytes, immunotherapy, immune exhaustion ...

ISOLATED ORBITAL CYSTICERCOSIS… CAUSE OF PTOSIS IN CABBAGE EATERS

Case Report of International Journal of Case Reports ISOLATED ORBITAL CYSTICERCOSIS... CAUSE OF PTOSIS IN CABBAGE EATERS Perwez Khan, Alok Ranjan, Jayati Pandey Deptt. of Ophthalmology, G.S.V.M Medical College, Kanpur PURPOSE: To report case of isolated orbital cysticercosis METHODS: Patients with drooping of eyelid were referred to our hospital. Patients were evaluated and investigated to find the cause of ptosis. RESULTS: Two patients with acute unilateral ptosis were referred to our hospital. Patients were investigated, blood test, stool tests and MRI were done to rule out the causes. In both the patients ptosis was due to involvement of LPS muscle by cysticercus larva. All the patients gave history of excessive consumption of cabbage and pork. The mainstay of treatment included oral albendazole (15 mg/kg/day) and oral prednisolone (1mg/kg/day) for 4 weeks. After 4 weeks, oral albendazole was stopped and oral prednisolone was slowly tapered over the next one month. The effect of above treatment was seen after few days with regression of swelling and improvement of signs and symptoms. CONCLUSION: Orbital cysticercus stands as one of the major causes of ptosis in the lower socioeconomic status people who are consuming mainly unhygienic leafy vegetables such as cabbage, burgers and undercooked pork. Therefore, these patients should be vigorously evaluated on scans (MRI and CT) so that early diagnosis can be made and treatment can be given to prevent the permanent visual loss or dissemination to brain. Keywords: Orbital cysticercosis ; Ptosis ; Taenia.solium ...

Dr. Xiaoning Luo
Professor, Department of Otorhinolarygology-Head and Neck Surgery, Guangdong General Hospital, Guangzhou, China

Dr. N.S. NEKI
Professor & Head, Dept.of Medicine, Govt. Medical College, Amritsar, India

Dr. Jitesh K. Kar
Clinical assistant professor, Department of Internal Medicine – Neurology, University of Alabama at Birmingham, Huntsville Regional Campus

Dr. Nisar Haider Zaidi
MBBS, MS, MRCS (Glasgow), FICS, FACS. Department of surgery, King Abdulaziz University Hospital , POBox-80215 Jeddah 21589 , Saudi Arabia

Dr. Giuseppe Lanza
Consultant Neurologist and Clinical Researcher, Department of Neurology IC of the “Oasi” Institute for Research on Mental Retardation and Brain Aging

Dr. Yousif Mohamed Y. Abdallah
Professor (Assistant), Radiological Science and Medical Imaging Department, College of Applied Medical Sciences, Majmaah University, Majmaah, Saudi Arabia

Dr. Karol Szyluk
District Hospital of Orthopedics and Trauma Surgery

Dr. Mohd Normani Zakaria
Chairman / Head of Hospital Unit / Assistant Professor / Consultant Audiologist, Audiology and Speech Pathology Programme, School of Health Sciences,, Universiti Sains Malaysia 

Dr. Dennis J. Mazur
Senior Scholar, Center for Ethics in Health Care, and Professor of Medicine, Oregon Health and Science University, Portland, Oregon USA

Dr. Marcos Roberto Tovani Palone
Department of Pathology and Legal Medicine, Faculty of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil.

Dr. Begum Sertyesilisik
Assoc. Prof. at the Istanbul Technical University

Dr. Jamunarani Veeraraghavan
Baylor College of Medicine, One Baylor Plaza, Houston, Texas 

Dr. Rajinder Pal Singh Bajwa
Niagara Falls Mem Med Center, Division of Infectious Diseases, 621 Tenth Street, Niagara Falls, NY

Dr. Can SARICA
Adiyaman University School Of Medicine, Department Of Neurosurgery, Adiyaman

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1. Avinaba Mukherjee, Sourav Sikdar, Anisur Rahman Khuda-Bukhsh. Evaluation of ameliorative potential of isolated flavonol fractions from Thuja occidentalis in lung cancer cells and in Benzo(a) pyrene induced lung toxicity in mice. International Journal of Traditional and Complementary Medicine, 2016; 1(1): 0001-0013. 
2. Vikas Gupta, Parveen Bansal, Junaid Niazi, Kamlesh Kohli, Pankaj Ghaiye. Anti-anxiety Activity of Citrus paradisi var. duncan Extracts in Swiss Albino Mice-A Preclinical Study. Journal of Herbal Medicine Research, 2016; 1(1): 0001-0006.

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Aims
International Journal of Case Reports (ISSN:2572-8776; DOI:10.28933/IJCR) is a peer reviewed open access journal publishing case reports in all kinds of diseases of all medical fields. Our aim is to provide a platform for authors from all countries to encourages publication of most recent case reports in all specialties. 

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Peer Review help ensure the quality of the publications. Manuscripts of International Journal of Case Reports will be peer-reviewed by invited experts in the field. The decisions of editors will be made based on the comments of the reviewers.

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International Journal of Case Reports (ISSN:2572-8776; DOI:10.28933/IJCR) is a journal to support Open Access initiative

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Scope: (Case reports from all medical fields.)

  • Allergy and Its Subspecialties
  • Anesthesiology and Its Subspecialties
  • Physical Medicine and Rehabilitation and Its Subspecialties
  • Urology and Its Subspecialties
  • Emergency Medicine and Its Subspecialties
  • Dermatology and Its Subspecialties
  • Medical Genetics and Its Subspecialties
  • Internal Medicine and Its Subspecialties
  • Diagnostic Radiology and Its Subspecialties
  • Neurology and Its Subspecialties
  • Psychiatry and Its Subspecialties
  • Obstetrics and Gynecology and Its Subspecialties
  • Ophthalmology and Its Subspecialties
  • Surgery and Its Subspecialties
  • Pediatrics and Its Subspecialties
  • Nuclear Medicine and Its Subspecialties
  • Preventive Medicine and Its Subspecialties
  • Radiation Oncology and Its Subspecialties
  • Pathology and Its Subspecialties
  • Family Medicine and Its Subspecialties
  • Immunology and Its Subspecialties

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