International Journal of Case Reports


A challenging diagnosis in a patient with Odynophagia

Case Report of International Journal of Case Reports A challenging diagnosis in a patient with Odynophagia Claudia Colomba1, Raffaella Rubino1, Rosario Maugeri2, Antonio Anastasia1, Paola Di Carlo1, Federica Paolini2, Riccardo Speciale2, Domenico Gerardo Iacopino2, Antonio Cascio1 1Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, Italy; 2Department of Experimental Biomedicine and Clinical Neurosciences, School of Medicine, Neurosurgical Clinic, University of Palermo, Palermo, Italy; 3 ENT Department of the University of Palermo, Italy. Tuberculous retropharyngeal abscesses are rare but potentially life-threatening manifestations of tuberculosis. We present herein a case of an 18-year-old male patient, a migrant from Somalia, accusing fever, odynophagia and neck pain. CT scan and MRI study of the neck showed a retropharyngeal and prevertebral abscess from C1 to D1 with the involvement of epidural space and spondylitis. Resolution of the abscess with few signs of residual spondylitis was achieved after surgical evacuation and antitubercular treatment. Keywords: Retropharyngeal abscess; Odynophagia; Tuberculosis ...

Acute Demyelinating Encephalomyelitis (ADEM) following rabies vaccination

Case Report of International Journal of Case Reports Acute Demyelinating Encephalomyelitis (ADEM) following rabies vaccination Lucia Cavanagh1*, Adriana M. Strutt2, Paul E. Schulz3 1Department of Psychiatry, Jane and Terry Semel Institute for Neuroscience and Human Behavior, University of California - Los Angeles, Los Angeles, CA, United States. 2Department of Neurology, Baylor College of Medicine, Houston, TX, United States. 3Department of Neurology, McGovern Medical School of UT Health Houston, Houston, TX, United States. Acute disseminated encephalomyelitis (ADEM) is an inflammatory demyelinating disease of the central nervous system (CNS). Its diagnosis can be challenging due to having varied clinical presentations, including a range of motor, speech, cognitive, and behavioral changes that can vary in frequency and intensity, and there being no strictly defined diagnostic criteria for it in adults. Here we present a 58-year-old White male who developed ADEM following an uncommon cause (i.e., rabies vaccination), which was difficult to diagnose due to atypical manifestations. Keywords: Acute disseminated encephalomyelitis (ADEM); rabies; vaccine; parkinsonism; cognitive dysfunction; neuropsychology ...

Fibromyalgia as A Sole First Presentation of Recurring Idiopathic Intracranial Hypertension in a child. A Case Report and Literature Review

Case Report of International Journal of Case Reports Fibromyalgia as A Sole First Presentation of Recurring Idiopathic Intracranial Hypertension in a child. A Case Report and Literature Review Sondos Altaraqji1, Rayan S. Terkawi2,3, Abdallah Alneirab2,3, Diyaa Rachdan4,5 and Khalid Mohamed1 1Pediatric Neurology Division, Sidra Medicine, Doha, Qatar 2Department of Pediatrics, Hamad Medical Corporation, Doha, Qatar 3Department of Pediatrics, Sidra Medicine, Doha, Qatar 4Ophthalmology Division, Department of Surgery, Sidra Medicine, Doha, Qatar 5Weill Cornell Medicine – Qatar Idiopathic intracranial hypertension (IIH) is a condition characterized by raised intracranial pressure (ICP) with no evidence of brain pathology, also known as pseudo tumor cerebri. Headache and visual obscuration are the most common presenting symptoms for IIH with a frequency of (68-84%) respectively. Other symptoms of IIH include neck pain, back pain, and radicular pain in the arms and legs resulting from increased spinal pressure and forced filling of the spinal nerves with CSF. Case summary: We present an 11-year-old boy known to have chronic kidney disease stage II, due to obstructive uropathy. He had a history of Idiopathic intracranial hypertension that was treated completely and condition resolved, then presented with generalized pains and aches without headaches or visual symptoms and found to have IIH for the second time, the symptoms resolved with appropriate treatment. Conclusion: Widespread pain and several other characteristics of IIH share similarities with characteristics of fibromyalgia (FM) and chronic fatigue syndrome (CFS), two overlapping chronic pain conditions. Keywords: Idiopathic intracranial hypertension; Fibromyalgia; Papilledema ...

Mesothelial Cyst in a Young Female: Case report and literature review

Case Report of International Journal of Case Reports Mesothelial Cyst in a Young Female: Case report and literature review Thabet Alghazal*1, Anwar Alzahrani2, Shomuk Alshamrani3, Jumanah Felemban4, Abdulwahed Meshikhes5 1King Fahad specialist Hospital-Dammam; 2King Fahad Hospital of the University-Alkhubar; 3Royal commission Hospital- Jubail; 4King Fahad Specialist Hospital-Dammam; 5King Fahad Specialist Hospital -Dammam & AlZahraa Hospital. Mesenteric cysts are rare intra-abdominal benign tumors (1 in 100,000 cases in adults) with various clinical presentations. [1,2] They commonly originate from the small bowel mesentery, although a proportion has been found to originate from the mesocolon, and retroperitoneum. [1,3] The formation of mesenteric cysts depends on the histologic origin, where they could be classified into cysts of lymphatic origin, cysts of mesothelial origin, cysts of enteric origin, cysts of urogenital origin, dermoid cysts and pseudocysts. [4,5] Diagnosis is extremely difficult since. The Mesenteric cyst is usually asymptomatic, but if symptomatic, abdominal pain (82%), nausea and vomiting (45%), constipation (27%) are the most common presenting symptoms. [2,3] The clinical finding of abdominal mass is encountered in more than 61% of the patients. [2,3]. As this condition is very rare and its symptomatology can resemble any other abdominal diseases, diagnosis is extremely difficult and incorrect preoperative diagnosis is often made. Hence, performing physical examination and conducting radiological investigations such as ultrasonography (USG) and computed tomography (CT) are important in making a correct diagnosis. [2,3] As well as cases of mesothelial cysts, they are typically asymptomatic but occasionally, their symptoms are vague and non-specific. [6,7] As mentioned above, imaging modalities such as USG, CT and magnetic resonance imaging (MRI) are great in identifying the character, size, location, surrounding tissues and the wall and content of the cysts. [7] Surgery is the treatment of choice, as a complete resection with negative borders is curative and often prevents recurrence. [3] ...

A NEW TYPE-2-LIKE CALR MUTATION IN ESSENTIAL THROMBOCYTHEMIA

Case Report of International Journal of Case Reports A NEW TYPE-2-LIKE CALR MUTATION IN ESSENTIAL THROMBOCYTHEMIA Mattia Brescini, dr, Maria Giovanna Loglisci, biotechnologist, Gioia Colafigli, dr, Luisa Bizzoni, dr, Sonia Buffolino, biologist, Daniela Diverio, biologist, Massimo Breccia, dr, Maurizio Martelli, full professor, Stefania Trasarti, dr* Hematology, Department of Traslational and Precision Medicine, Policlinico Umberto 1, Sapienza University, Rome, Italy. CALR mutations, together with JAK-2 and MPL ones, are recognized as “driver” mutations in Philadelphia-negative chronic myeloproliferative neoplasms (MPNs). Most frequent CALR mutations are Type-1 deletions (45-55% of cases) and type-2 insertion (32-42% of cases). These mutations are usually associated with younger age, higher platelet counts, lower leukocyte counts, lower hemoglobin levels and a higher incidence of transformation from ET to MF. Recognizing and describing cases with different mutations can be useful to create a database that might help clinicians to include these patients in risk categories and to guide the appropriate therapeutic choices. We report a case of a 77-years old woman who presented a new type-2 like CALR mutation. Keywords: CALR; Essential Thrombocythemia; Myeloproliferative Neoplasm ...

Dr. Xiaoning Luo
Professor, Department of Otorhinolarygology-Head and Neck Surgery, Guangdong General Hospital, Guangzhou, China

Dr. N.S. NEKI
Professor & Head, Dept.of Medicine, Govt. Medical College, Amritsar, India

Dr. Jitesh K. Kar
Clinical assistant professor, Department of Internal Medicine – Neurology, University of Alabama at Birmingham, Huntsville Regional Campus

Dr. Nisar Haider Zaidi
MBBS, MS, MRCS (Glasgow), FICS, FACS. Department of surgery, King Abdulaziz University Hospital , POBox-80215 Jeddah 21589 , Saudi Arabia

Dr. Giuseppe Lanza
Consultant Neurologist and Clinical Researcher, Department of Neurology IC of the “Oasi” Institute for Research on Mental Retardation and Brain Aging

Dr. Yousif Mohamed Y. Abdallah
Professor (Assistant), Radiological Science and Medical Imaging Department, College of Applied Medical Sciences, Majmaah University, Majmaah, Saudi Arabia

Dr. Karol Szyluk
District Hospital of Orthopedics and Trauma Surgery

Dr. Mohd Normani Zakaria
Chairman / Head of Hospital Unit / Assistant Professor / Consultant Audiologist, Audiology and Speech Pathology Programme, School of Health Sciences,, Universiti Sains Malaysia 

Dr. Dennis J. Mazur
Senior Scholar, Center for Ethics in Health Care, and Professor of Medicine, Oregon Health and Science University, Portland, Oregon USA

Dr. Marcos Roberto Tovani Palone
Department of Pathology and Legal Medicine, Faculty of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil.

Dr. Begum Sertyesilisik
Assoc. Prof. at the Istanbul Technical University

Dr. Jamunarani Veeraraghavan
Baylor College of Medicine, One Baylor Plaza, Houston, Texas 

Dr. Rajinder Pal Singh Bajwa
Niagara Falls Mem Med Center, Division of Infectious Diseases, 621 Tenth Street, Niagara Falls, NY

Dr. Can SARICA
Adiyaman University School Of Medicine, Department Of Neurosurgery, Adiyaman

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1. Avinaba Mukherjee, Sourav Sikdar, Anisur Rahman Khuda-Bukhsh. Evaluation of ameliorative potential of isolated flavonol fractions from Thuja occidentalis in lung cancer cells and in Benzo(a) pyrene induced lung toxicity in mice. International Journal of Traditional and Complementary Medicine, 2016; 1(1): 0001-0013. 
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Aims
International Journal of Case Reports (ISSN:2572-8776; DOI:10.28933/IJCR) is a peer reviewed open access journal publishing case reports in all kinds of diseases of all medical fields. Our aim is to provide a platform for authors from all countries to encourages publication of most recent case reports in all specialties. 

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Peer Review help ensure the quality of the publications. Manuscripts of International Journal of Case Reports will be peer-reviewed by invited experts in the field. The decisions of editors will be made based on the comments of the reviewers.

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International Journal of Case Reports (ISSN:2572-8776; DOI:10.28933/IJCR) is a journal to support Open Access initiative

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Scope: (Case reports from all medical fields.)

  • Allergy and Its Subspecialties
  • Anesthesiology and Its Subspecialties
  • Physical Medicine and Rehabilitation and Its Subspecialties
  • Urology and Its Subspecialties
  • Emergency Medicine and Its Subspecialties
  • Dermatology and Its Subspecialties
  • Medical Genetics and Its Subspecialties
  • Internal Medicine and Its Subspecialties
  • Diagnostic Radiology and Its Subspecialties
  • Neurology and Its Subspecialties
  • Psychiatry and Its Subspecialties
  • Obstetrics and Gynecology and Its Subspecialties
  • Ophthalmology and Its Subspecialties
  • Surgery and Its Subspecialties
  • Pediatrics and Its Subspecialties
  • Nuclear Medicine and Its Subspecialties
  • Preventive Medicine and Its Subspecialties
  • Radiation Oncology and Its Subspecialties
  • Pathology and Its Subspecialties
  • Family Medicine and Its Subspecialties
  • Immunology and Its Subspecialties

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