International Journal of Virology and Diseases


Epidemiological Profile of Tuberculosis in the Municipality of Limoeiro, Pernambuco, for the Period 2008-2013

Research Article of International Journal of Virology and Diseases Epidemiological Profile of Tuberculosis in the Municipality of Limoeiro, Pernambuco, for the Period 2008-2013 Andreza Bezerra de Lima¹*, Maria Eduarda da Silva Santana², Tamyres Camila Silva³, Emmanuela Kethully Mota dos Santos4, Maria Juliana Gomes Arandas5, Janaina Kelli Gomes Arandas6 Introduction: This study characterized the epidemiological profile of the reported cases of tuberculosis in the municipality of Limoeiro / PE, between 2008 and 2010. Methodology: This is an epidemiological, observational, retrospective study that used the (SINAN) obtained from the Epidemiological Surveillance of the Municipal Health Department, in which the data were analyzed according to the following variables: gender, age group, institutionalization status, area of residence, clinical form, type of entry , termination status, HIV serology. Results: In the study period, 347 cases of tuberculosis were reported. It was verified that males and individuals aged 15 years and over were the most affected by the disease, with 87.03% and 98.85% respectively. Regarding the institutionalization situation, 55.04% of the cases were institutionalized. The urban area accounted for 39.48% of the cases. The pulmonary form was the most predominant with 95.10%. The main mode of entry was the new case with 76.08%. Regarding the closure situation, the cure outcome was more frequent at 75.50%, mean treatment dropout was 3.75%, and TB-related death was 1.73%. TB / HIV coinfection represents 3.75% of the notifications, and 40.63% of the patients did not perform serology for HIV. Conclusions / Considerations: These results contribute to the knowledge of the epidemiology of tuberculosis in the municipality, thus providing subsidies for disease control planning and prevention actions, as well as suggestions for other studies and development of new public policies. Keywords: Infectious-contagious diseases, Epidemiology, Mycobacterium tuberculosis ...

The influence of oral health microcefalia

Review Article of International Journal of Virology and Diseases The influence of oral health microcefalia Santana, J.F¹; Santos, G.A²; França, L.C³, Ramos, L.V.S4, Lima, L.F.A5; Maia, C.S6 1, 2, 3, 4, 5Students of the Course of Dentistry - UFPE; 6Docente/Researcher of the Department of Histology and Embryology of UFPE Introduction: Microcephaly is a condition in which the baby’s head is smaller than normal. It is a clinical sign that may or may not be related to other morphological changes. Studies show that children with microcephaly are more susceptible to changes in the oral region. Objective: To verify the problems caused in the oral health of children affected by microcephaly and to relate the embryonic development and bone formation with neurological problems caused by microcephaly. Methodology: We conducted a research on databases such as Scielo and Lilacs, and sites such as PAHO/WHO and the Ministry of Health, using the descriptors: Microcephaly, Craniofacial Malformations, Oral Health. Results and Discussion: The research resulted in 4,000 articles, of which 40 were separated because they were related to the topic, but only 20 met the inclusion criteria. Neonates with head circumference two standard deviations below the mean should be considered as having microcephaly. For this diagnosis, the measurement should be done at least 24 hours after birth and within the first week of life. Recently, Brazil has started an outbreak of microcephaly related to Zika virus and studies confirm viral neurotropism with possible persistence in brain tissue and placental impairment. Some changes may be related to the multifactorial etiology of microcephaly, which involves genetic and environmental factors. Thus, microcephaly may interfere with organs of the stomatognathic system, influence craniofacial growth, and alter its dynamics. About 1638 children with microcephaly in Brazil have oral alterations including periodontal diseases, dental caries, malocclusion, micrognathia and delayed eruption. Conclusion: ...

Tracing of cervical cancer prevention examinations carried out in the city of Recife-PE

Research Article of International Journal of Virology and Diseases Tracing of cervical cancer prevention examinations carried out in the city of Recife-PE MONTE, P.R.A1; SANTOS, M.V.V2; ALMEIDA, T.G.S3; COSTA, L.F4 1,2,3Centro Universitário Mauricio de Nassau – UNINASSAU, 4Centro Universitário Mauricio de Nassau - UNINASSAU Introduction: Cancer of the cervix when diagnosed and treated early is a cause of preventable death. Because it is a neoplasm caused by human papillomavirus (HPV), the Pap test is a safe and efficient strategy for early detection in the female population. According to the Brazilian Guidelines for Cervical Cancer Screening (2016), the first two tests should be performed at annual intervals and, if both results are negative, the next ones should be performed every 3 years. Beginning at age 25 for women who have had or have had sexual activity and periodic examinations should be continued until age 64 in women without prior history of pre-invasive neoplastic disease and discontinued when women have at least two exams consecutive negatives in the last 5 years. In 2013, the Cancer Information System (Siscan) was established within SUS, integrating the Cervical Cancer Information System (Siscolo) and the Breast Cancer Information System (Sismama). In Pernambuco, 970 new cases are expected and, in Recife, 150 new cases, representing the second most frequent cancer in women in the State and in the capital. Objective: To track the number of cervical cancer screening exams conducted in the city of Recife-PE, Brazil. Methodology: The source used was the Cervical Cancer Information System (SISCOLO), in the period from 2009 to 2014, in women aged 12-64 years, residents of this city and SUS users. Results and Discussion: When comparing the number of exams performed each year, a significant quantitative decrease was observed: from 9019 exams in 2009 to 1171 in 2014, a decrease of almost ...

Detection of human papillomavirus in oral mucosa

Review article of International Journal of Virology and Diseases Detection of human papillomavirus in oral mucosa Paiva, E.M.C¹; Peres, A.F2; Morais, A.R.O3; Santos, D.C4; Araújo, D.F.B5; Siqueira, Y.M6 1,3,4,5,6Academics of the Centro Universitário Tabosa de Almeida ASCES-UNITA; Centro Universitário Tabosa de Almeida - ASCES-UNITA 2Docente of the discipline of Clinical Cytology of do Centro Universitário Tabosa de Almeida - ASCES-UNITA Introduction: According to the National Cancer Institute (INCA) 2017, Brazil shows high prevalence rates in malignant neoplasms with primary localization in the oral cavity, since oral cancer affects the lips and oral cavity. It is a multifactorial disease, derived from genetic, environmental or infectious factors (viruses) isolated or in association, causing cytogenetic changes that proceed through a somatic mutation sequence, resulting in uncontrolled cell proliferation. Objective: To study the detection of human papillomavirus (HPV) in the oral mucosa, making it possible to trace possible risk factors associated with its development. Methods: This is a descriptive cross-sectional study of the bibliographic review on the subject, monographs, dissertations, theses and books, comparatively analyzing the information from these research sources, making a discussion about the results of this survey. Results and Discussion: There are more than 100 types of papillomavirus identified, 24 of these related to the oral cavity. Transmission of papillomavirus to oral mucosa occurs by self-inoculation and through the practice of oral sex. Papillomavirus infection begins when the virus contacts the basal epithelial cells by a slow process of endocytosis, from the binding to a specific receptor on the surface of basal cells. Viral tropism is caused in part by the binding of specific viral surface proteins to certain host cell surface receptor proteins. Studies to detect the presence of papillomavirus in the oral mucosa reveal that this virus appears to persistently or frequently infect the mouth, including in children and adolescents ...

Dr. Bogdan-Ioan COCULESCU
Center for Medical-Military Research, Bucharest, Romania, and “Titu Maiorescu” University, Faculty of Medicine, Bucharest, Romania

Dr Tan Seok Tyug
Department of Healthcare Professional, Faculty of Health and Life Sciences, Management and Science University

Dr Pavan Kumar R Panchavati
Department of Family Medicine, University of Alabama at Birmingham

Dr Shashi Kant Tiwari
Department of Pediatrics, University of California, San Diego (UCSD), School of Medicine, Biomedical Research Facility II (Health Sciences)

International Journal of Virology and Diseases

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1. Avinaba Mukherjee, Sourav Sikdar, Anisur Rahman Khuda-Bukhsh. Evaluation of ameliorative potential of isolated flavonol fractions from Thuja occidentalis in lung cancer cells and in Benzo(a) pyrene induced lung toxicity in mice. International Journal of Traditional and Complementary Medicine, 2016; 1(1): 0001-0013. 
2. Vikas Gupta, Parveen Bansal, Junaid Niazi, Kamlesh Kohli, Pankaj Ghaiye. Anti-anxiety Activity of Citrus paradisi var. duncan Extracts in Swiss Albino Mice-A Preclinical Study. Journal of Herbal Medicine Research, 2016; 1(1): 0001-0006.

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