Virology and Diseases

  • Epidemiological Profile Of Congenital Syphilis In Alagoas

    Objective: To analyze the epidemiological profile of congenital syphilis in the state of Alagoas from 2015 to 2019. Methods: Epidemiological study characterized as descriptive, observational, retrospective and cross-sectional, carried out based on data collected from the Information System for Notifiable Diseases (SINAN) and made available by the Department of Chronic Conditions and Sexually Transmitted Infections. Results and Discussions: When observing the cases of congenital syphilis, 2019 saw a significant drop in cases compared to the years 2015 to 2018. Conclusion: It is concluded that the epidemiological profile of DES demonstrates that the number of cases is higher among children under 7 days of age, the mother’s age range between 20 and 29 years, the mother’s education level from 5th to 8th grade incomplete and race / color of the mother, brown. This reflects for health professionals to seek more strategies to eradicate the disease in the state and in Brazil.

  • The Pandemic In Prison: Dissemination Of Covid-19 Infection Among The Population Without Freedom: A Cut In The State Of Pernambuco

    Objectives: To conduct a retrospective analysis on the distribution of cases of COVID-19 in the population deprived of liberty belonging to the state of Pernambuco. Methods: This is a retrospective study conducted on secondary electronic databases in the public domain, exempted from the need for an appreciation by the Ethics Committee. The database consulted was of the Center for Strategic Information on Health Surveillance (CIEVS) in the State of Pernambuco. The reference period for collection was from April 1 to September 28, 2020. Epidemiological bulletins and virtual monitoring reports, available on the CIEVS website, were analyzed. The data were analyzed using descriptive statistical techniques based on obtaining absolute and percentage frequencies. Results: The State of Pernambuco has the sixth largest prison population in the country. There are 25,564 prisoners, 24,657 men and 907 women. Related to the distribution of cases of infection by the new coronavirus, of the 5,926 suspected cases, 1,476 were confirmed, 46 are still under investigation and 37 had inconclusive tests, which represents an infection rate of 5.77% of the prison population. These results reflect that the scenario of COVID-19 infection in Pernambuco is a cause for concern, both for the general population and among the prisioners. Conclusion: The results suggest that although only 5.7% of the prison population has been infected, prison units are spaces with a potential risk for the spread of COVID-19 infection. In addition, many of the prisioners are an effective risk group and, accordingly, they should be monitored with greater intensity.

  • Metabolic Alterations Of Patients With Acquired Immunodeficiency Syndrome

    Objective: To evaluate the metabolic changes in patients with acquired immunodeficiency syndrome. Methods: This is an observational analytical cross-sectional study that was carried out with 120 patients on regular use of antiretroviral therapy, from May to July 2018. The metabolic changes were determined through the collection of biochemical parameters: CD4, CD4 absolute, CD8, absolute CD8, hemoglobin, High-Density Lipoprotein, Low-Density Lipoprotein, triglycerides, and fasting blood glucose. Results: The lipid profile, in most individuals, showed serum values ​​of total cholesterol, triglycerides, and Low-Density Lipoprotein, within the normal range, while the serum levels of High-Density Lipoprotein were decreased by 53.6%, being related to the mean time disease of 8.7 years (± 6.1). As for hematological indices, 62 and 60 (80.5% and 77.9%) of the patients had adequate serum hemoglobin and hematocrit values, however, it was observed that those who had anemia lived with the virus for a longer time (9.27 years ± 6.89). When observing the parameters related to the immune system, it was seen that CD4 levels were low in 38% of patients, adequate absolute CD4 in 56.5%, increased CD8 in 90.7%, and absolute CD8 in 63%. Conclusion: It is known that metabolic changes, such as the decrease in serum levels of High-Density Lipoprotein are common in patients with the virus, as well as, it is known that the survival of these individuals is being prolonged by antiretroviral therapy, which can result in exposure important risk factors for cardiovascular disease. Emphasizing the importance of nutritional monitoring in this population.

  • Socioeconomic Profile Of Patients Living With Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome Followed In A School Hospital In Recife-PE

    Objective: Describe the socioeconomic profile of patients living with the human immunodeficiency virus in a Teaching Hospital in Recife-PE. Methodology: A cross-sectional study, carried out between April and November 2019. Identification, demographic and socioeconomic data were collected. The study was approved by the Research Ethics Committee of the Instituto de Medicina Integral Professor Fernando Figueira, under CAAE: 10262919.7.0000.5201. Statistical analysis was performed using SPSS version 13.0. Results: The sample consisted of 81 patients, with an average age of 37 years ± 11.3 years and 56.8% of females. The family income was 1714.9 ± 1533.5 reais and 46.8% of the individuals had some type of income. It was also possible to verify that, most of the patients had electric light (98.8%), water source by the public network (79.0%), mineral water (71.6%), television (95.1%), and internet (82.4%). Almost half of the individuals (46.9%) used the pit as a sanitary sewer. Conclusion: It can be concluded that the human immunodeficiency virus affects both individuals with low purchasing power and those who have better socioeconomic conditions.

  • Analysis of Cases of Tuberculosis Related to Diabetes Patients and the Concurrent Use of Licit and Ilicit Drugs in the State of Pernambuco

    INTRODUCTION: Tuberculosis is an infectious disease caused by the bacterium Mycobacterium tuberculosis. In Brazil, TB is considered a public health problem due to the high rate of cases, ranking 20th in the notified cases ranking. The transmission of the disease is related to some lifestyles, since there is a higher incidence in patients with diabetes Who use illicit and licit drugs such as tobacco and alcohol. Factors such as diabetes, alcoholism, smoking and illicit drugs favor the spread of the disease and may shift from latent to active tuberculosis. OBJECTIVE: Given the above, the objective of this study was to verify the cases of tuberculosis related to patients with diabetes and the use of licit and illicit drugs in the state of Pernambuco from 2015 to 2018. METHODS: This is a descriptive study with approach. To verify the incidence of tuberculosis in a given group. For this data were obtained from the SINAM / DATASUS database. The variables used were: diabetes, alcoholism, smoking and illicit drugs. RESULTS: From 2015 to 2018, 19,733 cases of tuberculosis patients were reported. Of these 1,890 (10%) were affected by diabetes, and in 2017 the most affected with (26.5%). Greater susceptibility to develop tuberculosis due to hyperglycemia, leading to insulin dependence which generates indirect cellular effects. It was observed that of the notified by tuberculosis about 4,584 (23%) stated to use alcohol. Alcohol is also considered a risk factor as it alters the immune response due to liver damage, thus leading to an increase to develop TB with an increase of (26.6%) in 2017. TB involvement in patients who have tobacco use was 4,258 (22.1%) with an increase of (31.5%) in 2018, the tobacco is a risk factor because it has reduced immune response due to ciliary dysfunction, developed by cigarette smoke . Given the…

  • 2019 Coronavirus Disease (COVID-19) Outbreak: A Review Article

    In December 2019, an outbreak of severe acute respiratory syndrome coronavirus 2 infections occurred in Wuhan, Hubei Province, China and spread across China and beyond. On February 12, 2020, WHO officially named the disease caused by the novel coronavirus as Coronavirus Disease 2019(COVID-19). The COVID-19 is a respiratory illness caused by a coronavirus and pandemic is now a major global health threat. Coronaviruses (CoV) belong to the genus Coronavirus with its high mutation rate in the Corona viridae. This review focuses to have a preliminary opinion about the disease, the ways of treatment, and prevention in this early stage of COVID-19 outbreak.


    Introduction. Measles is an acute infectious disease, whose etiological agent is a RNA virus of the paramyxovirus family. It is transmitted by aerosols through nasopharyngeal secretion within four to six days before the appearance of rash up to four days after. The clinical manifestations of the disease are quite characteristic and may evolve with serious complications, being one of the main causes of morbidity in malnourished or immunosuppressed children and under one year old. Currently the triple viral vaccine is the only way to prevent the disease, providing protection against measles, and also for mumps and rubella. However, some outbreaks are becoming more frequent, including in Brazil and may be related to several factors such as individuals who were not vaccinated by individual decision, thus exposing unvaccinated populations to the pathogen. Objective. To verify the prevalence of measles cases in Brazil from 2018 to 2019. Method. A descriptive cross-sectional study was conducted by surveying the numbers of cases reported by measles in the regions of Brazil from 2018 to 2019, available from the World Health Organization (WHO) database. Result and discussion. To prepare the study, we analyzed the information that was available in the World Health Organization (WHO) database. From November 26, 2018 to October 19, 2019, there were a total of 16,991 confirmed measles cases in eleven states of Brazil. In 2018, the state of Amazonas had the highest notification with 11,156 cases, with 9,695 (89.9%) confirmed, 1,442 (12.9%) discarded and 19 (0.2%) remaining under investigation. It was observed that 6,217 (55.7%) are male and the highest concentration is in the age group of 15 to 29 years, with 5,078 (45.5%), when calculating the incidence of confirmed cases by age group, notes a higher incidence in children under 1 (2,191.8 / 100,000 inhabitant). In 2019, 6,828 cases were reported,…


    Introduction: The discovery of HIV compromises individuals in various areas of their lives, which can compromise their quality of life. Objectives: To investigate the topics covered in online journals about the factors that influence the quality of life of people living with HIV / AIDS. Methodology: Integrative Revision carried out in October 2018 in the Regional Portal of the Virtual Library (VHL), applying as descriptors “HIV”, “Acquired Immunodeficiency Syndrome”, “Quality of life” and using as a cutback the last 5 years, with a certain question The study sample consisted of 10 original articles, divided into three thematic categories: “alterations” and “quality of life” related to HIV / AIDS. bodily, clinical, emotional, “” social support, “” orientation about disease. Results: The study sample consisted of 10 original articles, divided into three thematic categories: “body, clinical, emotional,” “social support,” “orientation about the disease. Conclusion: The quality of life of individuals with HIV / AIDS reflects significantly in the maintenance of their well-being, which highlights the importance of attending to factors that may modify this situation and be able to go beyond the pathology.

  • The contributions of the population about prevention practice of Dengue

    Introduction: Dengue is the world’s most important arboviral disease in terms of number of people affected ans is transmitted by mosquitoes Aedes Aegypti. The main strategy for epidemic prevention and control is population behavior in the prevention and insecticide fumigation. Objective: The following study aims to describe the contributions of the population about prevention practice of dengue. Materials and Methods: This is a descriptive research. Studies of any design published from 2012 to 2016 available in english, portuguese and spanish were included. The survey was conducted in the Scientific Electronic Library Online (SciELO). Results and Discussion: Six articles were found that match the eligible criterias. In accord to them, it was realized that the Brazilian population has a slouch behavior in practice prevention of mosquito outbreaks, providing opportunities that the mosquito prolife, and not getting success in disease control. This may occur because of poor infrastructure conditions in most cities, as well as the lack of preventive actions both private and public initiative. Conclusion: It was clear that the Brazilian population needs to engage in preventive actions related to dengue, but also charge more effective action of public policies to assist them in combating the proliferation of the mosquito.


    The yellow fever is treated of a disease infectious endemic sharp viral of origins in Africa and in areas in South America. According to OMS (World Organization of the Health), they are dear annually 200.000 cases of the disease. The etiological agent of the yellow fever belongs to the family Flaviridae and to the gender Flavirirus, which is the responsible for other diseases in the man. The treatment of the yellow fever is constituted with uses of painkillers and antitérmicos with attention specifies of acid acetilsalicílico and flowed in the pictures hemorrágicos. This work intended to accomplish a bibliographical revision on the yellow fever. Now there are several indicative factors of reurbanização of the disease, the incidence of the virus happens in endemic areas, infecting the man and his/her natural host