International Research Journal of Obstetrics and Gynecology


HPV-Negative Vulvar Squamous Cell Carcinoma in a 21-year-old Patient

Review Article of International Research Journal of Obstetrics and Gynecology HPV-Negative Vulvar Squamous Cell Carcinoma in a 21-year-old Patient Dânia Ferreira1*, Paulina Corgo2, Vanda Patrício3, Amelia de Almeida4 1Hospital de Braga. 2Centro Hospitalar Medio Ave, Famalicão. 3Instituto Português de Oncologia do Porto. 4Centro Hospitalar Medio Ave, Famalicão. Vulvar Squamous Cell Carcinoma usually occurs among women in their 60s or 70s. There are a limited number of reports of vulvar cancer cases younger than 30 years. These patients have usually risk factors such as human papillomavirus (HPV) infection. In this report, the authors present a rare case of invasive vulvar squamous cell carcinoma in a 21-year-old patient without HPV infection. Surgical treatment was performed, followed by adjuvant radiation therapy. Keywords: HPV; Vulvar Squamous Cell Carcinoma ...

Relation between pregnant women and the Brazilian Unified Health System (SUS): Screening and diagnosis of GDM

Review Article of International Research Journal of Obstetrics and Gynecology Relation between pregnant women and the Brazilian Unified Health System (SUS): Screening and diagnosis of GDM Matheus Alves Siqueira de Assunção1*, Francisco Henrique da Silva2, Aline Fernanda Carneiro Cardoso3, Evandro Valentim da Silva4, Hellencléia Pereira Cunha3, Fálba Bernadete Ramos dos Anjos2 1Department of Histology and Embryology, Federal University of Pernambuco,  Recife, Pernambuco, Brazil 2Department of Biochemistry, Federal University of Pernambuco, Recife, Pernambuco, Brazil 3Graduada em Farmácia pela Federal University of Pernambuco, Recife, Pernambuco, Brazil 4Clinical Hospital, Federal University of Pernambuco,  Recife, Pernambuco, Brazil The existence of a complex health system is capable of providing the necessary care for the mother and mother, but the levels of complexity of this treatment vary according to the need and severity of the situation in which the pregnant woman is ebcibtra. From this perspective, this chapter will address the relationship between pregnant women and the Brazilian Unified Health System, as well as the care and diagnosis of Gestational Diabetes Mellitus. Keywords: SUS, Complexity, Treatment, Diabetes ...

Gestational Diabetes Mellitus: highlights about biochemical agents that subscribe its physiopathological mechanism during gestational trimesters

Review Article of International Research Journal of Obstetrics and Gynecology Gestational Diabetes Mellitus: highlights about biochemical agents that subscribe its physiopathological mechanism during gestational trimesters João Ricardhis Saturnino de Oliveira1 *, Aedson Pereira da Silva2, Bianka Santana dos Santos1,3, Priscila Pereira Passos4, Anselmo Queiroz Alves5, Francisco Henrique da Silva6 , Fálba Bernadete Ramos dos Anjos6, Vera Cristina Oliveira de Carvalho1, Matheus Alves Siqueira de Assunção6, Vera Lúcia de Menezes Lima1 1Department of Biochemistry, Federal University of Pernambuco, Recife, Pernambuco, Brazil; 2International Faculty of Paraíba, João Pessoa, Paraíba, Brazil; 3Life Sciences Center, Campus Agreste, Federal University of Pernambuco, Caruaru, Pernambuco, Brazil; 4University Center Maurício de Nassau, Recife, Pernambuco, Brazil; 5Hematology and Hemotherapy Hospital of Pernambuco, Recife, Pernambuco, Brazil; 6Department of Histology and Embryology, Federal University of Pernambuco, Recife, Pernambuco, Brazil Gestational Diabetes Mellitus (GDM) is a common complication in which hyperglycemia goes by physiological state, beneficial to the embryo, to metabolic condition that causes damage to both mother and child. Placental hormones, insulin resistance, visceral fat tissue, dyslipidemia, and other biochemical agentes, subscribe the physiopathological mechanisms that lead to GDM. Nowadays, there are mRNAs, proteins, and even vitamins being associated with GDM risk and its pathophysiology. These new pathways usher a new horizon to discover and describe other important parts of metabolism that play a key role to GDM. With a larger picture of pregnant women metabolism prior and after GDM, better predictors and efficient treatment can be managed. Keywords: Gestational Diabetes Mellitus, biochemical agents , physiopathological mechanism , gestational trimesters ...

Gestational diabetes: diagnosis, care, and influence on fetus

Review Article of International Research Journal of Obstetrics and Gynecology Gestational diabetes: diagnosis, care, and influence on fetus Viviane Ramos Bandeira 1,2, Francisco Henrique da Silva2, João Alberto Lins de Lima3,5, Rafael Artur Queiroz Cavalcanti de Sá2, Matheus Alves Siqueira de Assunção4, Fálba Bernadete Ramos dos Anjos4, Bárbara de Azevedo Ramos4 1Graduating in Nutrition, UNIBRA, Recife, Pernambuco, Brazil; 2Department of Biochemistry, Federal University of Pernambuco, Recife, Pernambuco, Brazil; 3Departent of Chemistry, Rural Federal University of Pernambuco, Recife, Pernambuco, Brazil; 2Department of Antibiotics, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil; 4 Department of Histology and Embryology, Federal University of Pernambuco, Recife, Pernambuco, Brazil; 5 Department of Antibiotics, Federal University of Pernambuco, Recife, Pernambuco, Brazil Gestational diabetes mellitus (GDM) is characterized by the WHO as a condition of hyperglycemia detected for the first time during pregnancy, with blood glucose levels that do not meet the diagnostic criteria for DM. There are some hormones produced by the placenta and increased by pregnancy, such as placental lactogen, cortisol, and prolactin. In which, they can reduce the performance of insulin at its receptors and, consequently, increase insulin production in healthy pregnant women. Prenatal care is essential to prevent complications for women and children. Thus, an individualized diet should be indicated, exercise during pregnancy, and delivery should be monitored. If the recommendations do not normalize the condition of GDM, spontaneous abortions, the formation of excess amniotic fluid, congenital malformations, restricted fetal growth, and even the death of the mother and fetus may occur. Keywords: diabetes, pregnancy, diabetes mellitus ...

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1.Vila Nova I.C, Alves R.R.V, Maia-Neto L.S, Rodrigues F.T.M, Almeida M.M.C, Rodrigues P.M.B.To observe changes of female sex hormones after chemical induction of Diabetes Mellitus.International Research Journal of Obstetrics and Gynecology, 2018, 1:5 
2.Moraes S.R.T, Vasconcelos R.P, Andrade R.M.A, Konze V.S, Ramos R.C.F. Prevalence Of Venereal Diseases In Professional Sex Women: A Review Of The Last 10 Years.International Research Journal of Obstetrics and Gynecology, 2018, 1:4

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International Research Journal of Obstetrics and Gynecology (ISSN:2639-6009;DOI:10.28933/IRJOG) is a peer reviewed open access journal publishing research manuscripts, review articles, editorials, letters to the editor in Obstetrics and Gynecology(Indexing information).

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International Research Journal of Obstetrics and Gynecology

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