American Journal of Basic and Applied Sciences


COMPLIANCE AND DOSAGE FORM PREFERENCE IN IRON/ FOLIC ACID SUPPLEMENTATION IN ANTENATAL CARE MOTHERS

Research Article of American Journal of Basic and Applied Sciences COMPLIANCE AND DOSAGE FORM PREFERENCE IN IRON/ FOLIC ACID SUPPLEMENTATION IN ANTENATAL CARE MOTHERS, AYDER COMPREHENSIVE SPECIALIZED HOSPITAL, NORTHERN ETHIOPIA: A CROSS SECTIONAL STUDY Teshome Abegaz, Arega Gashaw School of Public health, Mekelle University Background: Globally, iron deficiency anaemia is one of the major health problems of pregnant women. Less than one percent took iron supplements during their last pregnancy, and the major problem with iron-folate supplementation during pregnancy is non-compliance. Objective: The aim of this study is to assess prevalence of Compliance and Dosage Form Preference in Iron folic acid supplementation (IFAS) in Antenatal Care (ANC) visit others, Ayder Comprehensive Specialized Hospital, Ethiopia. Methods: A cross sectional study was conducted at Ayder comprehensive specialized hospital antenatal care from Oct.2018 – Feb.2019. Result: The total number of study participants was 278 and 172 (63.3 %) were in compliance with iron / folic acid supplementation. The five associated variables indicated significant association at 95% confidence interval for compliance to iron/folic acid supplementation was, age less than 28 years AOR=.044, [.015-.128] , a monthly income AOR=10.304, [3.220-32.970] family size AOR=.144 [.036-.565], four and more ANC visits AOR=4.193, [1.689-10.411, first trimesters and second trimester AOR=21.168, [6.297-71.158] and AOR=4.458, [1.592-12.485] , AOR=4.193, [1.689-10.411] all with p value < 0.05. Conclusion: In this study, compliance with prenatal iron folate supplementation remains very poor as 63.3%. Mother’s age, monthly income, number of ANC visits, family size and trimesters have been found to be significantly correlated with compliance during pregnancy with prenatal iron foliate supplementation. Therefore, during the ANC visit health workers and health extension workers must regularly advise on IFAS benefits to strengthen adherence to IFAS during current and future pregnancies. For the implementation and refinement of iron supplementation program strategies and acceptable dosage forms, more ...

DRUG INDUCED HEPATOTOXICITY AMONG TB AND TB/HIV CO-INFECTED PATIENTS

Research Article of American Journal of Basic and Applied Sciences DRUG INDUCED HEPATOTOXICITY AMONG TB AND TB/HIV CO-INFECTED PATIENTS IN AYDER COMPREHENSIVE SPECIALIZED HOSPITAL, TIGRAY, ETHIOPIA Arega Gashaw and Afewerk Tesfay School of Pharmacy, Mekelle University Background: Drug-induced hepatotoxicity is the most prevalent side effect that lead to the failure of new drug candidates or withdrawal from the market and is a significant clinical problem that contributes more than 50% of acute liver failure. Objective: The objective of this study is to assess the prevalence and associated risk factors of drug-induced hepatotoxicity among TB or TB/HIV co-infected patients in ACSH, Mekelle, Ethiopia. Method: A retrospective cross sectional method was conducted in ACSH on the prevalence and associated risk factors of drug-induced hepatotoxicity among TB or TB/HIV co-infected patients from January to April 2019 E.C. Result: Out of 164 participants, 16 of them had developed hepatotoxicity. After bivariate logistic regression analysis, Predictor variables with p-value < 0.25 by bivariate analysis were analysed using multivariable logistic regression analysis and Art regimen [AOR=0.038, (CI95%) (0.002-0.846); p=0.038], CD4 count less than 50 [AOR=0.031, (CI95%) (0.00-0.64); p=0.08] and disseminated of TB [AOR=0.042, (CI95%) (0.001-0.88); p=0.030] as independent predictors of drug induced hepatotoxicity. Conclusion: The prevalence of DIH was 9.8 %. Results suggest that in the presence of disseminated pulmonary TB and CD4 count in HIV positive patients and those who are on Efavirenz based ART medication should be closely monitored for the occurrence of hepatotoxicity to prevent morbidity and mortality. Keywords: Tuberculosis, Drug induced hepatotoxicity, Risk factor, CD4, ART ...

FACTORS ASSOCIATED WITH CEREBROVASCULAR ACCIDENT PATIENTS

Research Article of American Journal of Basic and Applied Sciences FACTORS ASSOCIATED WITH CEREBROVASCULAR ACCIDENT PATIENTS, AYDER COMPREHENSIVE SPECIALIZED HOSPITAL, MEKELLE, TIGRAY, ETHIOPIA Teshome Abegaz, Arega Gashaw School of Public health, Mekelle University Background: Cerebrovascular accident (CVA) is a problem that refers to a group of conditions that affect the circulation of blood to the brain. The objective of this study was to identify factors related to cerebrovascular accident patients in the Ayder Comprehensive Specialized Hospital. Method: A retrospective cohort study design was conducted in the Ayder Comprehensive Hospital from January 2015 to August 2016 and followed for a total of 20 days during the admission period. Data was collected from a database of electronic medical records and medical charts using a structured data extraction tool. Kaplan-Meier, log rank test and Cox-proportional hazard regression were used. STATA V.13 program was used for data entry, cleaning and analysis. Result: From 292 CVA case patients, 42(14.4%) died and (80.95%) were died with in the 7 days of hospital stay and their median survival time was also 7 days. Factors associated with CVA mortality were: positive history of hypertension (HR=4.8, 95%, CI= 1.486 - 16.018), positive history of diabetes mellitus (HR=2.0, 95%, CI= 1.086 - 3.789), Stroke sub type as haemorrhagic (HR= 2.1, 95%, CI= 1.070 - 4.160), admitted in intensive care unit (HR= 2.48, 95%, CI= 1.166 -5.306) and increased age (HR= 5.1, 95%, CI= 1.725 - 15.487) Conclusion: The risk rate of patients at an earlier time was high, and there was more death in the intensive care unit than any other medical wards. Hypertension was the most common risk factor for both types of cardiovascular accidents. Ischemic stroke subtype, diabetes mellitus and rising age were also associated survival factors. Keywords:  Stroke, Cerebrovascular accident, intensive care unit, associated factors ...

STATUS AND CHALLENGES OF AVAILABLE FEED RESOURCES AND IT’S QUALITY UNDER THE CHANGING CLIMATE

Research Article of American Journal of Basic and Applied Sciences STATUS AND CHALLENGES OF AVAILABLE FEED RESOURCES AND IT'S QUALITY UNDER THE CHANGING CLIMATE IN ADAMI TULU DISTRICTS OF EAST SHOA ZONE, ETHIOPIA LELISA DIRIBA1* AND MENGISTU URGE2 1Oromia Agricultural Research Institute, Adami Tulu Agricultural Research Center, Batu, Ethiopia. 2Department of Animal and Range Science, Haramaya University, Haramaya, Ethiopia. The study was conducted in Adami Tulu Jido Kombolcha (ATJK) district of the East Shoa Zone Oromai Region, Eethiopia, with the objectives to assess the existing status of feed resource under climate change and examine chemical composition. Feed sample from grazing lands (protected communal (PC), protected private (PP) and unprotected communal (UnPC) and crop residues were used for chemical composition analysis (23 from the natural pasture (NP) and 48 from crop residues (CRs). Out of 23 herbaceous species identified in ATJK district, Cynodon dactilon in ATJK district was the dominant grass species. The average mean DMY (ton ha-1) of grass obtained from PPGL (2.43) and PCGL (2.36) was significantly (P<0.01) higher than that from UnPCGL(1.18) in ATJK . The mean value of CP contents of CRs in ATJK district were 3.5±0.17 for maize stover (MS) to 6.5±0.93 for Haricot bean (HCB) straw. The NDF contents of CRs were between 63.5±1.83 for HCB to 79.74±1.24 for maize stover (MS). The ADF contents of CRs varied from WS (49.12±2.82) to HC (52.63±1.16) in ATJK district. Generally, the nutritive values of the evaluated feed resources were lower than the minimum and should supplement with protein and energy source. The analysis of meteorological data of 30 years of ATJK district indicated that; as temperature increase, the annual rainfall decrease and increases the rate of crop water use. This situation of climate change affects directly or indirectly the nutritive values and yields of the crop, natural ...

Dr. Boumediene Haddad
Associate professor (lecturer and Scientific Researcher), Department of Chemistry, Dr. Moulay Taher University

Dr. Alfred DACI
Polytechnic University of Tirana, Mathematical and Physical Engineering Faculty, Department of Mathematics

Dr. Mohammad Mehdizadeh
PhD of Weed Science, University of Mohaghegh Ardabili

Dr. Karol Szyluk
District Hospital of Orthopedics and Trauma Surgery. b41-940 Piekary Śląskie, Bytomska 62 str. 

Dr. Raga Mohamed Elzaki Ali
Department of Consumer Sciences and Agribusiness, College of Agricultural and Food Sciences, King Faisal University

Dr. Shankar T Battase
Assistant Professor and Head, Dept. of Commerce and Management, Govt. First Grade College Sindagi

Dr. ABHISHEK SHUKLA
Assistant Professor, R.D. Engineering College Technical Campus, Ghaziabad

Dr. Hossein Alizadeh
Research Officer, Lincoln University

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1.Melo, M.C.F, Macêdo, T.S, Oliveira, J.C, Araújo, M.G.C, Vidal, A.K.L. Odontologic atention on oncological practice.American Journal of Basic and Applied Sciences, 2018, 1:5. DOI:10.28933/ajbas-2018-06-1805 
2.Ramos L.V.S, Santos G..; Lima L.F.A, França L.C. , Santana J. F., Trindade M. O.Polysomnography and bruxism.American Journal of Basic and Applied Sciences, 2018, 1:3. DOI:10.28933/ajbas-2018-06-1803

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