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American Journal of Histology and Cytology

Histology and Cytology, Recent Articles

RESEARCH ON BRAIN TUMORS IN MEXICO: A BIBLIOMETRIC ANALYSIS FROM LATIN AMERICA

Review Article of American Journal of Histology and Cytology Research on Brain Tumors in Mexico: A Bibliometric Analysis from Latin America Rubio Carmen PhD1, Tena Martha M.D. 1, Rojas Daniel A. M.D. 1, Sotelo Julio, PhD. 1, Lee Angel M.D. 2 1Instituto Nacional de Neurología y Neurocirugía, Mexico City, Mexico; 2Comisión Coordinadora de Institutos Nacionales de Salud y Hospitales de Alta Especialidad, Mexico City, Mexico Background: Bibliometrics is a completive method of research and analyses useful to understand the collective contributions of a given scientific community. The detail of the quantity (productivity) and impact as a surrogate marker of quality can shed light on what we have done (number of articles) and how we impact others (citations). It also shows the direction the community can take for further research, guided by its shortcomings and successes. The publications of Latin American medical institutions on brain neoplasms have never been studied. Objective: Analyze a clinical and experimental approach, identifying core journals, type of article, increase of published material with time, number of citations. Additionally, we identified the most researched topics involved in brain tumor literature. Material and methods: We harvested the articles published by at least one author from the Instituto Nacional de Neurología y Neurocirugía from Mexico from its inception in 1964 to 2020. Key bibliometric parameters, as the journal of publication, type of paper, number of articles, and citations were recorded. Results: In cerebral neoplasms, our institution produced 291 articles (clinical versus experimental: 227 vs. 64). With a modest productivity before 2000, the production had increased 8-fold by 2019. The main topic is glioblastoma, also with the highest number of citations. Researchers prefer to conduct original investigations rather than subject reviews. Most papers were published in Archivos de Neurociencias (institutional journal produced in Spanish), most papers published in English were ...
Histology and Cytology, Recent Articles

“TWO IN ONE”- A RARE CASE OF NEOPLASTIC COLLISION TUMOR

Case Report of American Journal of Histology and Cytology  “Two in One”- A rare case of neoplastic collision tumor Vanessa Fonseca-Ferrer*, MD; Alba Rivera-Diaz, MD; Luis-Gerena-Montano, MD; Christian Castillo-Latorre MD; Sulimar Morales-Colon, MD;Andres Velazquez-Garcia, MD; William Rodriguez-Cintron, MD. “Pulmonary and Critical Care Fellowship Program” VA Caribbean Health care System, San Juan, Puerto Rico. Collision tumors are a rare group of tumoral pathologies characterized by their composition, which is based by the presence of two or more tumor types affecting the same anatomical site and separated by distinct tumor borders. These tumors may be a combination of either malignant or benign tumors [1]. Collision tumors are classified as independently coexisting neoplasms which have different genetic, behavioral, and histological features separated by a distinct demarcated border but coexist within the same organ [2]. These tumors tend to have distant immunohistochemical and morphological differences which aid in diagnosis, but can lead to confounding imaging findings, which in times, make diagnosis more challenging. According to literature this tumor tends to grow simultaneously or following each other in sequence of less than 2 months apart [3]. Accurate classification and diagnosis of these tumors is important for proper treatment options, as well as better patient outcomes. Here will be discussed a case of a rare form of collision tumor, compose of a primary lung adenocarcinoma with a mucosa-associated lymphoid tissue (MALT) lymphoma. Keywords: Collision tumor, lung adenocarcinoma, lymphoma, combined tumor ...
Histology and Cytology, Recent Articles

PATHOLOGICAL APPROACH TO PLEURAL MALIGNANT MESOTHELIOMA

Case Report of American Journal of Histology and Cytology Pathological Approach to Pleural Malignant Mesothelioma Vanessa Fonseca-Ferrer, MD; Luis Gerena-Montano, MD , Héctor A. Nieves Figueroa, MD; William Rodriguez-Cintrón, MD VA Caribbean Healthcare System, San Juan P.R; Pulmonary and Critical Care Medicine Exposure to asbestos can lead to asbestosis or malignancy 10-40 years after initial exposure [1]. Although its use has been banned in multiple countries, past occupational exposure leads to most cases that we see in present time.  Malignant mesothelioma is an insidious and rare neoplasm that can arise from mesothelial surface cells, being Malignant Pleural Mesothelioma (MPM) the most common type. Lifetime risk of developing mesothelioma among asbestos workers can be as high as 10 percent and latency period is approximately 30-40 years since time of exposure to development of disease [2]. Annual incidence in the united states is approximately 3,300 cases per year [3]. Median overall survival of patients with advanced unresectable disease is approximately 12 months [4]. Clinical suspicion should arise in patients with previous exposure to asbestos who present with pleural thickening and/or effusion with associated respiratory symptoms. Most symptoms are nonspecific such as chest pain, dyspnea, cough and night sweats. Initial evaluation includes chest x-ray, contrast enhanced CT of the chest to find pleural abnormalities, thoracentesis and closed pleural biopsy. However, difficulties establishing diagnosis have been illustrated on studies where thoracentesis and pleural fluid cytology only yields diagnosis in 26% of cases. The diagnosis, then, is established by morphologic and immunohistochemistry findings of cytologic and surgical specimens. Keywords: Pathological Approach; Pleural Malignant Mesothelioma ...
Histology and Cytology, Recent Articles

PATHOLOGICAL CHANGES IN THE RATS’ EYES AFTER THE ADMINISTRATION OF OIL MACHINERY FLUID THROUGH STEREOTAXIC SURGERY

Research Article of American Journal of Histology and Cytology Pathological Changes In The Rats’ Eyes After The Administration Of Oil Machinery Fluid Through Stereotaxic Surgery Martha Lilia Tena-Suck1*, Alma Ortiz-Plata2, Joaquín Manjarrez3, Wilhelm Moreno4, Carmen Rubio4 , Francisca Fernández-Valverde2 1Instituto Nacional de Neurología y Neurocirugía. Departamento de Neuropatología. Ciudad de México. 2Instituto Nacional de Neurología y Neurocirugía. Laboratorio de Neuropatología experimental Ciudad de México. 3Instituto Nacional de Neurología y Neurocirugía. Laboratorio de formación Reticular. Ciudad de México. 4Instituto Nacional de Neurología y Neurocirugía.  Departamento de Neurofisiología Ciudad de México. Purpose: To achieve a relationship between oil machinery fluid (OMF) and the damage this fluid produces in several eye structures. In neuro-oncology patients, we know there are several parasellar tumors; one of them is the craniopharyngiomas that can produce a cystic structure containing an oily material. It has been denominated as an oil machinery fluid (OMF); this fluid has not yet been widely studied. It is a widely held view that it produces toxic effects in the brain and other structures. This paper aims to see the toxicity of the OMF when administered directly in the brain and the changes produced in the rats’ eyes. Methods: 30 Wistar rats were divided into three groups, control, sham and experimental; the oil machinery fluid was obtained directly from human patients during surgery. The oil machinery fluid was administered to the rat thalamus by stereotaxic surgery. The subjects were under observation after the surgery for five weeks and sacrificed once the observation period ended. Finally, immunohistochemistry was performed on tissue recovered from the eyes. Results: We observed that in the experimental group, there was an increase in glucose levels, the coloration of the eyes changed to a pinkish color, the lenses changed opacity, there were histological changes in the retina, and a reduction of ...

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American Journal of Histology and Cytology1

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