Recent Articles

  • Multiple septic emboli and myocardial infarction due to vaso-invasive Rhizomucor pusillus infection in a hematologic patient

    We present a case of a 63-year-old hematologic patient with pulmonary vaso-invasive zygomycosis with Rhizomucor pusillus after a second stem cell transplantation (SCT) for myelodysplastic syndrome, complicated by multi organ failure, myocardial ischemia and infarction. Zygomycosis is common in immunocompromised patients, especially after hematopoietic stem cell transplantation (HSCT). Mucor species have devastating vaso-invasive properties causing hematogenic dissemination. Antemortem diagnosis may be difficult due to negative cultures. Despite adequate treatment outcome tends to be poor. Cardiac zygomycosis is rare. In our patient, the clinical course and imaging results of the myocardial infarction are most consistent with coronary plaque rupture possibly provoked by severe vaso-invasive pulmonary infection and multi-organ failure.


    Objective: Perform the histomorphometric study of the following regions: areas of perivillous fibrin deposition; thickness of the endothelial layer of the vessels; analysis of Tenney-Parker changes. Analyze the Placental Index (IP). Results: It was seen that the weight of the placentas increased according to the weight of the newborn, however, when the variable PI was analyzed as being decisive for the development of a risk-free pregnancy, it was found that this parameter was not significant between the groups studied. (p


    Objective: The objective of this study was to determine the prevalence of pregnant colonization by group B Streptococcus (GBS) and to verify whether socioeconomic and demographic conditions are risk factors for colonization by this bacterium. Method: This cross-sectional study included the collection of sociodemographic data through a questionnaire and authorization to access the result of the cultivation of vaginal swabs for the investigation of GBS of 50 women treated at the Unified Health System (SUS) in a laboratory in the municipality of Medianeira, PR, between august and september 2020. Results: The population studied showed a 14% prevalence of colonization by GBS, within national and world standards. Among the factors analyzed, the only significant and protective association was living with fewer people in the same house, up to two people, reducing the risk of developing a positive culture for GBS by more than 5 times (5.54) when compared to pregnant women who live with more than 3 people in the same residence (p


    Objective: This review aims to investigate the scientific production aboute the health education in adolescence for the responsible sexual practice. Methods: This is an integrative review, using scientific articles indexed in the Virtual Health Library (VHL). We searched for articles in the databases LILACS, SCIELO and BDENF and the following descriptors were used: Pregnancy in Adolescence; Nurse; Health Education. In the search, 20 articles were found, of which, only 14 met the objective of the study. Inclusion criteria: full text available, original article, publication between 2014 and 2019 available in Portuguese and included in the proposed theme. Results: Adolescent pregnancy is considered a relevant public health problem, due the high prevalence across the country. The profile of pregnant adolescents is between 12 and 19 years, most of them single, low education, mixed race, housewives. The literature shows that early pregnancy impairs the female emancipation, results the school dropout, early entry into the labor market, disqualification, violence, decreased opportunities and also being associated with the spread of IST’s. Due to this situation and the future repercussions, unplanned pregnancy among adolescents requires holistic approaches to promote health and prevention measures. Conclusion: The nurse is essential in the development of preventive and educational skills with adolescents, establishing a strategy aimed at preventing teenage pregnancy, creating groups with purposes in the promotion of health and prevention of IST’s/early pregnancy, with the objective of making young people aware of the importance of active participation in health education actions.

  • Identification Of Parasitic Infections In Food Handlers And The Imminent Risks Of Transmission To School-Aged Children

    Introduction: Most diseases transmitted by food contaminated by protozoa and/or helminths are originated from food improper handling. This fact is related to poor hygiene conditions in the food handling environment or the practices of food handlers. Objective: The aim of this study was to identify parasitic diseases in food handlers, as well as the risk of transmission to school-aged children. Methods: This is a literature review accomplished through researchers in Pubmed, Academic OneFile, SciELO and Google Scholar. The review comprised 40 articles published in the period from 2009 to 2019. In order effect the review, were included in this study literature reviews and original articles, identified in the aforementioned databases and which met the inclusion criteria: having their publication in indexed journals, articles with abstracts and full texts available online, articles published in Portuguese, English or Spanish in the last ten years. Studies whose year of publication was less than 2009 were excluded. Results: Enteroparasitosis are a serious public health problem that affects the world population. This fact is mainly related to the ingestion of contaminated food, having a direct connection with those who handle it. Conclusion: Therefore, food handlers have an important role in the transmissibility of diseases and food security.

  • Brazilian Infectious and Parasitic Diseases Child Mortality between 2014 and 2018

    Objectives: Determinate which children are more likely to die due to infectious and parasitic diseases in order to indicate which groups require more attention from the health system. Methods: Data from the Mortality Information System (SIM) by the Informatics Department of the Unified Health System (DATASUS) regarding deaths from infectious and parasitic diseases were collected. All records by year and region of death and race and sex of children between 0 and 19 years were considered. Results: In the 5 years, 14,659 infant deaths due to infectious and parasitic diseases were recorded in Brazil, an average of 2,931.8 (± 323.8) per year. There is a 19.5% reduction between 2018 and 2014, that is, 5 years. The highest concentration of records is in the Northeast region, close to Southeast, with 33.2% and 32.4% respectively. Children under 1 year old are majority, with 52.1% while 5 to 9 years old are minority, 7.2%. As for sex, there is a small difference, 54.8% of the records are male. Most children are brow, 49.7%, followed by white, with considerably less, 34%. Conclusions: Brown children, under 1 year old and residents of the Northeast or Southeast are, according to statistics, more prone to fatal outcome of infectious and parasitic diseases. From this profile, it can be inferred that race and age are determining factors for child survival. Measures such as guidance to parents during prenatal care on preventing infections and parasites should be instituted, as well as childcare control and child vaccination in primary care.


    Aim: Frontal linear scleroderma, also known as ‘‘en coup de sabre,’’ is a congenital deformity characterized by atrophy and furrowing of the skin of the front parietal area above the level of the eyebrows. In most cases it occurs as a single paramedian line that may be associated with hypoplasia of underlying structures and facial hemiatrophy. In case of a wide lesion many reconstructive strategies have been proposed. The modern approach is aimed at augmentation of the tissue deficiency by using lipostructure and tissue regeneration. Autologous fat transfer (AFT) seems to be an effective strategy to restore the normal volume and contour of the face while providing a source of adipose-derived stem cells (ADSCs) with a multilineage differentiation potential. Methods: In this report, we present a rare case of linear scleroderma en coupe de sabre which was successfully managed with three stages of autologous fat grafting. Conclusion: The proposed uses for ADSCs in tissue repair and regeneration are quite impressive. Recent works on ADSCs would suggest that adult cells may prove to be an equally powerful regenerative tool in treating congenital and acquired maxillofacial disorders. More importantly, physicians, researchers and international associations need to cooperate in informing clinicians about what practices are based on evidence and to encourage support of additional research. There is increasing interest in a possible therapeutic effect of ADSCs from processed lipoaspirate for a wide spectrum of clinical applications in the facial and craniofacial area. AFT can be used in any facial area where soft tissue is lacking or where there is scarring, producing natural and long-lasting results. Mesenchymal stem cells represent a great tool in regenerative medicine. However, more definitive studies are needed to answer specific questions regarding the best technique to be used and the role of ADSCs. Autologous fat grafting provides a safe…

  • Preparing A University Hospital Neonatal Intensive Care Unit for Covid-19 Pandemic and Country Lockdown

    Jordan is one of the earliest countries that took a very strict approach to contain COVID-19 pandemic by declaring a country lock down. Our neonatal intensive care unit is a level three 30 beds unit. The shortage of neonatal nurses, doctors, and of respiratory support devices are the major existing challenges. During COVID-19 pandemic, those two issues were magnified. This paper will shortly discuss the measures taken as a preparedness for COVID-19 Pandemic in our unit. Team development and work schedule: The medical knowledge about COVID-19 was foggy, however; teamwork is the only ev-ident thing. Our team included, the neonatologists, pediatric intensivist, pediatric pul-monologists, in addition to the infectious disease specialist. The team also included three of our senior residents, and the neonatal unit head nurse. To enhance communication, we created a WhatsApp group (Peds COVID -19). Among this group, unidentified Patients’ information, in addition to recent publications and sci-entific opinions, were shared. Meeting with the obstetric department was done to famil-iarize both teams with the measures taken on both sides. The neonatal care is provided by two neonatologists. The in-house care providers are the pediatric residents. Senior residents are well-trained on neonatal resuscitation, endotra-cheal intubation, and umbilical venous catheterization. During COVID-19 lock down, residents were split into separate teams. Neonatal team, the pediatric floor team, and the emergency room team, each team had their sleeping room and lounges. The consultants did rounds daily, the in-house team consisted of two senior residents, and a junior resident. they did a 24-hour shift every four days and are off duty for the next three days. Regarding the nursing staff schedule, their work schedule changed from an 8- hour shift to a 12- hour shifts schedule. The aim was to promote staff well-being, minimize the number of staff who could potentially be exposed…

  • Fever is not a symptom in COVID -19. None of the diseases require fever as its symptom

    We have been hearing for centuries that ‘fever is not a disease but a symptom’. Physicians say that fever is a symptom of diseases like flu to cancer. The conservative fever definition, diagnosis, and treatments are based on fever as a symptom. All the studies related to fever as a symptom of a disease have been done without knowing the Purpose of the temperature of fever is. In the current COVID -19 epidemic situation, it has great importance. Because Fever is considered as an important part of Corona disease. Not knowing the purpose of temperature of fever, how can fever included as a symptom in COVID -19? What is the symptom in COVID -19 according to symptom definition? In COVID -19 up to 80% of patients have no fever. Why up to 80% of patients with the COVID -19 virus have no fever? Is it because there is no need for the care of fever or is it because the disease is free of symptoms? Without knowing the Purpose of the temperature of fever, how can fever included in the symptom definition? Any evidence to establish that fever is a symptom in COVID -19? Is temperature between 38o to 41o centigrade can be symptom of a disease? Most of the diseases may not have fever. Sometimes it disappears. Then, is fever a symptom of which disease? Is fever a symptom? what are the scientific criteria or parameters necessary for a Symptom? What we will do to prove a symptom? Symptom Definition? What is the use of Symptom Definition? As with any or all other definitions, symptom definition should describe the symptom scientifically. If it cannot describe clearly, there is no use of a symptom definition.

  • Diplomatic Victory of the Kosovo Liberation Army

    In the dissolution of Yugoslavia, Serbian nationalism played a crucial role with the project of creating a greater Serbia, using military violence to achieve the goal of this project. The northern republics such as Slovenes, Croats and Kosovo Albanians had the strongest reaction against this project, since after the first pluralist elections in Yugoslavia, political parties seeking independence from Belgrade came to the helm of these republics. The actions of national movements of the Slovenians, Croats, Bosnians, Kosovo Albanians, Macedonians and Montenegrins for independence, have been a reaction to the project of Serbian nationalism for the creation of a greater Serbia. In these new circumstances created in the Yugoslav federation, Kosovo Albanians profiled the demands for a sovereign and independent state of Kosovo, legitimizing it with the referendum held under conditions of occupation and with a sovereign vote for the independence of Kosovo. Despite the creation of some parallel institutions such as education and the obedience of Western diplomacy for a peaceful solution to the Kosovo issue. This was not achieved until an armed resistance from Kosovo Liberation Army (KLA) started in Kosovo, that the Kosovo issue was imposed on the diplomacies with international influence to start taking important decisions towards the solution to the Kosovo issue. Due to the KLA war, the contact group took the historical decision to organize an international conference in Rambouillet of France, with a concrete peaceful plan for Kosovo. Rambouillet’s decisions were rejected by the Yugoslav government, thus forcing NATO military intervention to stop crimes against Albanian civilians by Serb forces. The efforts of the Kosovo Albanians to get out of the Serbian occupation had been imposed, even though as such they were insufficient to achieve success for nearly a century, but due to the international diplomacy and the sacrifice of the Albanian national…