American Journal of Cardiology Research and Reviews


Chemotherapy-induced cardiotoxicity: Preliminary report from a tertiary cancer centre in India

Research Article of American Journal of Cardiology Research and Reviews Chemotherapy-induced cardiotoxicity: Preliminary report from a tertiary cancer centre in India Dr Suwarna Tambade MBBS, DNB- Medicine, Dr Sagar Bhalerao MBBS MD Oncology, Dr Rucha Sule MBBS, MD Psychiatry Dr Rajnish Nagarkar MS, MRCS (Edin), DNB BSS (UK), MNAMS HCG Manavata Cancer Centre, Nashik, India. Cancer has emerged as a major public health issue in India owing to significant epidemiological and demographic transition. As per literature, the overall ten-year survival rate for cancer is at 50% across the 20 most common malignancies. However, the ten-year survival rate is even more high, i.e. approximately 80% or higher for breast, melanoma, lymphoma, and uterine cancers. Contrary to the improved long-term cancer survival rates there has been an increase in adverse cardiac effects of cancer treatment. A retrospective analysis of patients admitted at HCG Manavata Cancer Centre, Nashik was conducted. The study was conducted at a single center comprising of 115 participants. Anthracyline chemotherapy has remained a mainstay treatment approach for cancer patients. Cardiotoxic side-effects of anthracyline chemotherapy regimens often limits their dosing. Although anthracylines have been associated with improved cancer outcomes, there remains an increased risk of cardiovascular morbidity and mortality. Doxorubicin-induced cardio toxicity was 5.45% while trastuzumab cardio toxicity was 5.26% (Table 4). The estimated cardio toxicity rate for our two-year follow-up was 4.08% for all specified chemotherapy regimens. The early detection of cardio toxicity by appropriate follow-up and monitoring is essential. Evaluation of patients using LVEF as a key parameter would help prevent irreversible cardio toxic events. Our preliminary report may act as a base for researchers and academicians to conduct and review ongoing chemotherapy regimens. Keywords: Chemotherapy-induced cardiotoxicity, Preliminary report, Tertiary cancer centre, India ...

RVOT Septal Pacing: Short review of History and Technical Requirements for successful implantation

Review Article of American Journal of Cardiology Research and Reviews RVOT Septal Pacing: Short review of History and Technical Requirements for successful implantation Sudeb Mukherjee Institute Of Cardiovascular Science, Institute Of Post Graduate Medical Education and Research, Kolkata-700020. The idea of Right Ventricular Outflow Tract (RVOT) septal pacing is based on the fact that the septal region of the RVOT and mid RV are the first zones of the ventricle to depolarise , suggesting that pacing from these areas on the right side of the septum would achieve as normal a contraction pattern as possible. This mini review describes short history of pacemaker and evolution of concept of physiological pacing like RVOT Pacing and its technical aspects of successful implantation. Keywords: Right Ventricular Outflow Tract (RVOT), Physiological Pacing ...

Hematological Change in Dogs Infected by Babesia Canis From Recife/Pernambuco

Research Article of American Journal of Cardiology Research and Reviews Hematological Change in Dogs Infected by Babesia Canis From Recife/Pernambuco Osório, M.O1, Albuquerque, E.N2, Accioly, C.C3, Behar, J.N.P4 1,2,3Psicóloga do Instituto de Medicina Integral Professor Fernando Figueira - IMIP, Tutora do Curso de Psicologia da Faculdade Pernambucana de Saúde - FPS 4Psicóloga do Instituto de Medicina Integral Professor Fernando Figueira – IMIP Introduction: The canine babesiosis is a disease caused by the intra-erythrocyte hematozoa Babesia canis, B. gibsoni and B. vogeli, mainly transmitted by Rhipicefalus sanguineus tick. In Brazil, the most common species is B. canis. Cases of canine babesiosis have been reported in several Brazilian states, and may cause serious damage to the health of animals. Objective: this study aims to analyze the hematological alterations of dogs treated at a veterinary clinic. Methodology: the research was retrospective, exploratory, descriptive and cross-sectional with quantitative-qualitative approach, and it was carried out at the clinic Bicho Estimado - Cordeiro, Recife-PE. Data collection was performed in the database of the Clinic laboratory, where reports of complete blood count and hematozoal examination were consulted, referring to the period from May 2012 to December 2014. Results: 716 laboratory reports were analyzed. A mean positivity of 20.11% was found for canine babesiosis, diagnosed by the blood draw technique stained by Giemsa. With regard to the hemogram, the following results were obtained: erythrocytes with an average value of 5.36 million/μL [reference value (VR)= 5,5 to 8,5] and platelets 183.5 thousand/μL (200-500 thousand/μL). Discussion: The hemogram showed the presence of anemia, with values of hemoglobin below the reference values. In the leukogram, monocytopenia and mild neutrophilia were observed. He also had thrombocytopenia and a high positivity for babesia. Conclusion: the results showed that babesiosis affects dogs of this region with a relevant frequency, causing alterations in some hematological parameters ...

Psychological Care Occurs in Pre and Postoperative Cardiac Valve Replacement Surgery

Research Article of American Journal of Cardiology Research and Reviews Psychological Care Occurs in Pre and Postoperative Cardiac Valve Replacement Surgery Osório, M.O1, Albuquerque, E.N2, Accioly, C.C3, Behar, J.N.P4 1,2,3Psicóloga do Instituto de Medicina Integral Professor Fernando Figueira - IMIP, Tutora do Curso de Psicologia da Faculdade Pernambucana de Saúde - FPS 4Psicóloga do Instituto de Medicina Integral Professor Fernando Figueira – IMIP Introduction: Cardiovascular diseases affect many individuals and their medical evaluation identifies the need for surgery, such as myocardial revascularization, valve replacement, among others. Cardiac valve replacement is a possibility for patients to promote their quality of life, which requires the performance of a multidisciplinary team, and the psychological support to the patient collaborates for its recovery. Objective: To describe how psychological care occurs in pre and postoperative cardiac valve replacement surgery. Methodology: Experience report. Results and discussion: In the preoperative period of this surgery, the psychologist performs an interview to evaluate the patient, analyzes whether he has a history of mental disorder and establishes a host and attachment for follow-up, and in the postoperative period, focuses on recovery and psychological support to the patient, aiming to raise awareness of the quality of life. Conclusion: The insertion of the psychologist in the health team is essential for the patient care in this surgery, offering psychological support and speech space to express the patient’s desires before surgery and the chronicity of this disease. Keywords: Cardiac surgery; Valvar replacement; Psychology ...

Dr. Arnon Blum
Professor and Head of the Department of Medicine, Faculty of Medicine, Bar Ilan University

Dr. Antonio Manenti
Associated Professor of Surgery at the University of Modena (Italy)

Dr. Luca Zanoli
Department of Clinical and Experimental Medicine, School of Nephrology, University of Catania, Italy

Dr. Ravinder Reddy Gaddam
Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa, USA

Dr. Richard Kones
Director, MD, FAHA, FESC, FRSM, FCCP, FAGS, FRSH, FRSB, Cardiometabolic Research Institute, 8181 Fannin St, Bldg 3, Unit 314, Houston, TX 77054 USA

Dr. Erich Cosmi
Associate Professor of Obstetrics and Gynecology, Department of Woman and Child Health, University of Padua, Italy

Dr. Elena Cavarretta
Assistant Professor, Dept. of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, corso della Repubblica 79, 04100 Latina Italy

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1.Suwarna Tambade, Sagar Bhalerao, Rucha Sule, Rajnish Nagarkar. Chemotherapy-induced cardiotoxicity: Preliminary report from a tertiary cancer centre in India.American Journal of Cardiology Research and Reviews, 2018, 1:7. DOI:10.28933/ajcrar-2018-10-0501 
2.Sudeb Mukherjee. RVOT Septal Pacing: Short review of History and Technical Requirements for successful implantation. .American Journal of Cardiology Research and Reviews, 2018, 1:6 

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American Journal of Cardiology Research and Reviews (ISSN:2637-4935; doi:10.28933/ajcrar) is a peer reviewed open access journal publishing research manuscripts, review articles, editorials, letters to the editor in Cardiology Research and Reviews   (Indexing information).

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American Journal of Cardiology Research and Reviews

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