Evaluation of laboratory risk indicator for necrotizing fasciitis (Lrinec) scoring system for diagnosis of necrotizing fasciitis in patients presenting with soft tissue infection
Necrotizing soft tissue infection represents a diverse process; the term itself encompasses a continuum ranging from pyoderma to life threatening infections (clostridial gas gangrene with myonecrosis, anaerobic cellulitis, and severe, necrotizing vibrio infections). These can occur in any anatomical area but the commonest site is the extremities. Necrotizing fasciitis is often underestimated because of the lack of specific clinical findings in the initial stages of the disease. The paucity of specific cutaneous signs to distinguish necrotizing fasciitis from other soft tissue infections such as cellulitis makes the diagnosis extremely difficult. The first and most important consideration for an accurate, prompt diagnosis is to have a high index of suspicion. It has been shown by numerous studies in the past that early recognition and surgical intervention at the earliest is the sole factor in preventing the morbidity and mortality in patients with necrotizing fasciitis [1-3]. So a scoring system which is easy to follow and cost effective with high positive and negative predictive value is required. One such scoring system is the LRINEC scoring system devised by Wong et al [4] in 2005 which claims to have a positive predictive value of 92.0% and negative predictive value of 96.0%. The mortality in necrotizing fasciitis is as high as 34%. [5] We evaluated LRINEC scoring system in patients presenting with symptoms and signs suggestive of soft tissue infection that progresses to necrotizing fasciitis in Sri Ramachandra Medical College and Hospital, Porur, Chennai over a period of two years.
Application of comprehensive evaluation method based on combination weight in valve workshop layout
The evaluation index system and evaluation method for the reliability of current workshop facility layout have not yet formed the standard. Taking the facility layout plan of valve production workshop as the research object, 9 evaluation indexes were put forward from four aspects of working environment, layout cost, production flexibility and management convenience, and a comprehensive evaluation system of valve production workshop layout was established. The AHP- entropy weight method was used to calculate the index weight. Based on the survey data and experts’ opinions, the evaluation model is used for analysis and evaluation. The evaluation results of the facility layout plan of valve production workshop are consistent with the reality. The results show that the weight method of this model not only considers the objective opinions of workshop personnel, but also uses the knowledge and experience of experts, which makes the workshop facility layout evaluation more objective and accurate, and provides reference for the standards of workshop facility layout evaluation.
Intra Cholecystic Papillary Tubular Neoplasm – A Case Report Of A Rare Differential Diagnosis Of Carcinoma Gall Bladder
We present a case report of a 57 year old lady who presented with complaints of right sided upper abdominal pain. The patient was initially diagnosed with carcinoma gall bladder(CAGB) by CECT Abdomen and PET CT imaging studies. Intra cholecystic papillary tubular neoplasm of the gall bladder(ICPN) was diagnosed after histopathological examination of the radical cholecystectomy specimen. ICPN can be managed with a cholecystectomy if the diagnosis is known pre operatively as the prognosis for ICPN is much better as compared with that for gallbladder adenocarcinoma.
Integration through friendships in school classes – A study of pupils with a migrant background in school friendship networks at primary and secondary schools in Germany
This paper deals with the integration of migrant children in informal communication networks in primary and secondary schools in Germany. The basic assumption is that these networks can serve as an indicator for the networking and embedding that take place within the class community and therefore can be used to investigate the integration of pupils with a migrant background. The initial results of our network analytical study reveal that pupils with a migrant background are well integrated into class networks. The study discloses that the migrant background does not serve as a conclusive characteristic of the pattern of class networks. The pupils are more or less networked with each other regardless of their migrant background, though it did emerge that children and adolescents born abroad, in particular, are far more likely to have outgoing relationships that remain unreciprocated. Remarkable is, that results from primary school correspond with data from secondary school.
The Use of ICT Resources for Teaching Social Studies: Does the Availability of ICT Resources Matter?
The paper explored the availability of information and communication technology (ICT) resources and the extent to which these resources influence the use of ICT in teaching Social Studies. The study setting was in the Awutu Senya district of Ghana. A descriptive survey design and quantitative approach were adopted for the study. From a target population of fifty-seven (57), 46 were sampled from which 39 participated in the survey. Means and standard regression were employed for the investigation. The testing of hypothesis was made possible through the use of structured equation modelling. The study concluded that ICT resources were inadequate for teaching Social Studies and that the use of ICT resources in teaching Social Studies in the district was low. The reason was evident based on the low level of ICT resources in the district. The study also concluded that there was a positive significant relationship between availability of ICT resources and its use in the teaching of Social Studies.
Ship navigation safety risk assessment based on genetic algorithm and BP neural network
In order to ensure the safe navigation of ships and reduce the occurrence of marine accidents, through the analysis of ship historical navigation safety accident data and related accident literature research, taking into account various aspects such as marine meteorology, cargo loading, ship status and crew quality. Construct a ship navigation safety evaluation body. The BP neural network algorithm is used to design the ship navigation safety risk network structure. The sea damage data is used as the network input sample to train the BP neural network and data fitting. At the same time, the genetic algorithm is introduced to find the individual corresponding to the optimal fitness, and the weight and threshold of the network are further optimized. The purpose is to improve the accuracy of data fitting. The optimized BP neural network evaluation results show that there are many indicators affecting the safety of the ship’s navigation, and the relationship between the indicators is complicated. The optimized BP neural network utilizes the characteristics of online adaptive learning, which eliminates the construction of complex relationships among various indicators within the structure, and solves the difficult problems in ship risk assessment to a certain extent.
A Semi Organic Non-linear Optical Crystal: Synthesis, Growth and Characterization of Novel Thiosemicarbazide Magnesium Chloride
Single crystals of thiosemicarbazide magnesium chloride (TSCMC) a semi organic nonlinear optical (NLO) material have been grown from aqueous solution by a slow evaporation technique. The grown crystals have been subjected to single crystal X-ray diffraction studies to identify of the structure. FTIR and optical transmission spectra reveal the optical properties of the grown crystals. The thermal behavior of TSCMC was investigated using the TG–DTA studies. Dielectric measurements were made over a wide range of frequencies for different temperatures. The second harmonic generation (SHG) efficiency for the grown crystals was determined using the Kurtz powder technique.
CHARACTERIZATION OF BIOACTIVITY OF EXTRACTS OF THE PLANT SPECIES JACARANDA RUGOSA A.H. GENTRY
The use of plants by man as a way to treat diseases is an ancient practice and widely used within the communities. Plants said to be medicinal present in their composition substances capable of altering the systematic functioning of organs, and may influence the treatment of diseases. The branch of science that studies plants and their ethnofarmacologic characteristics has attracted industries and researchers to elucidate their real biological influences in the organism. The Jacaranda rugosa, native plant of the caatinga biome, has been used in the treatment of infections and skin wounds and in the treatment of diseases. In order to evaluate the bioactivities of this species, the methodology of phytochemical prospecting was used, through thin layer chromatography, the verification of the antioxidant potential of leaf and branch extracts, through techniques such as neutralization of DPPH and ABTS radicals, in order to identify the functioning of the lity and the performance of cellular protection against oxidizing agents. In addition, microbiological techniques were used to evaluate the efficiency of extracts in acting as bactericide against disease-causing pathogens. As results, phytochemical prospection demonstrated the presence of secondary metabolites tannins, flavonoids and coumarins, the analyses of antioxidant activities by jacanda rugosa’s DPPH radical showed considerable activities from 62.5 mg/ml. The analysis of the neutralization of ABTS radicals demonstrated efficacy of 46% and 49% of ability to react against antioxidant substances. Against the microorganisms Salmonella spp.and Staphylococcus aureus, there was the activity of the extract for Salmonella spp in 5 mg/mL of the extract, but there was no activity for S. aureus..
ANTIOXIDANT ACTIVITY AND HEMOTOXICITY OF MEDICINAL PLANT OF THE CAATINGA DOMAIN: AMBURANA CEARENSIS (FABACEAE)
Amburana cearensis is a medicinal species popularly known as “cherry” or “aroma amburana” that has wide distribution in South America, being characteristic of Seasonal Forests. It also occurs in Semideciduous Seasonal Forest, restricted to rocky or limestone outcrops; in Submontane Deciduous SubmontanaSeasonalForest; in Dense Ombrophilous Forest (Atlantic Forest) and even in caatinga/dry forest. Taking into account the growing interest in the search for agents that act in the face of oxidative stress, without causing toxic effects to biological systems, the present study aimed to investigate the phytochemical composition and evaluate the antioxidant and hemotoxic activities in vitro of the aqueous extract obtained from the shells of Amburana cearensis (EAAc). Hemaglutination wasevaluated for human erythrocytes collected from people with the presence of O+ blood. In the face of the tests, Amburana cearensis presented significant results for antioxidant activity without causing erythrocyte hemolysis, highlighting the importance of the species as a source of antioxidant agents, which are recognized for blocking the evolution and acting to combat symptoms triggered by diseases associated with oxidative stress.
Evaluation of the Antioxidant Potential of Artisanal Liqueurs Produced From Fruits of the Caatinga Biome
Plant extraction is a common practice performed in community with the presence of native species with strong population interest. For many Brazilian regions, extractivism acts as a complement of income for the population. The present work aimed to evaluate artisanal liqueurs produced in local communities of the State of Pernambuco in order to observe the antioxidant potentials present during production stages. For this, trials were performed with dpph and abts radicals. All the liqueurs evaluated showed antioxidant potential, with expressive results through the sequestration of the DPPH radical, comprising values of 50 CI between 0.5 and 2.25.