American Journal of Clinical Research and Reviews

  • Dentist Surgery Performance Potentially Maligan Injury And Smoking Habit: Case Report

    Objective: To report the conduct of the dental team in the face of a patient with a potentially malignant lesion and who had difficulty quitting smoking. Methods: We described the clinical management of the injury and conduct in the face of the smoking habit of a female patient, 57 years old, melanoderma, denied alcoholism and a smoker for 30 years, referred to the Dentistry Service of Hospital Universitário Oswaldo Cruz. Results: An incisional biopsy and histopathological examination of the lesion were performed, which showed hyperplasia, hyperkeratosis and papillomatosis of the squamous epithelium, without signs of malignancy, corroborating the hypothesis of Leukoplakia. It was recommended that she quit smoking, emphasizing the prevention of the malignant transformation of the pathology and promotion of healthy habits. After that, 2 more excisional biopsies were performed to completely remove the lesion. The patient, after diagnosis, reported having stopped the habit and was being followed up with a pulmonologist and dental team. After a year and a half, in a return visit, the patient reported having returned to the habit. The importance of quitting the habit was reinforced and it was referred to psychology, since it showed interest in stopping the use of cigarettes again. Conclusion: In view of the diagnosis of a potentially malignant lesion and difficulty in smoking cessation, the role of the dental team in informing about cigarettes, in the pathogenesis of this lesion, and the importance of avoiding them for the preservation of health, in addition to continuous monitoring with patients.

  • Association Between Perceived Academic Stress And Suicide Behavior Among College Students From Pernambuco

    OBJECTIVES: To verify whether there is an association between perceived academic stress and suicidal behavior in young people in the university community. METHOD: Cross-sectional study approved by ethics committee (n°2,581,563), with a sample of 609 undergraduates from the Federal University of Pernambuco from: health, human sciences and exact sciences from 17 to 50 years. For the collection, we used: Mini International Neuropsychiatric Interview, Questionnaire of Academic Experiences reduced version, and a sociodemographic questionnaire. The data were tabulated in the SPSS program in version 21.0. Descriptive and inferential statistical techniques were used for analysis, considering a significance level of 5%. RESULTS: Of the sociodemographic data, 34.6% (n=211) were in the age group of 21 to 23 years, the majority were female, 64.5% (n=393). There was a significant difference in economic organization, the university students of human sciences presented lower per capita family income than health students (p

  • Territorialization As An Instrument For Expanding The Look Into The Territory: Experience Report

    Objective: To describe the experience of undergraduate students in the process of territorialization of some micro areas in Recife. Methods: Work based on academic practices of the discipline Occupational Therapy in Public Health – UFPE, in the 2nd semester of 2019, where students follow the professional performance in Primary Care. Among the activities carried out by the Extended Nucleus of Family Health and Primary Care, where the occupational therapist is inserted, there is the territorialization that, in this experience, took place in two meetings, specifically in some micro areas of the Health District VIII. Results: During the walk in the territory, the Community Health Agents presented the history of the community and reported that the community initially had a very industrialized profile. Subsequently, families began to establish themselves and take ownership of the place where they live until today, with several establishments such as schools, community spaces, squares, etc. that strengthen their identity The morbidities that most affect the elderly, young and male population are, respectively, chronic diseases, Sexually Transmitted Infections and infectious diseases. Territorialization is important in the process of planning interdisciplinary interventions and through it, the biopsychosocial dimensions are recognized and bring necessary discussions for all levels of care (COUTINHO, 2017). Conclusion: After the experience of Territorialization, it was possible to understand part of the complexity that is the territory, as well as to identify the main demands of the visited micro areas. Together with the NASF team, the occupational therapist can facilitate health education activities not only with the population itself, but also with professionals from the Family Health Unit.

  • Considerations On Human Immunodeficiency Virus (Hiv) Disease Mortality In Brazil Between 1998 And 2017

    Objective: Analyze mortality rates of the HIV disease in Brazil in a period of 20 years to determinate the behavior of the rates and the pattern of the victims. Methods: Data were collected from the Mortality Information System (SIM) by the Informatics Department of the Unified Health System (DATASUS) regarding deaths from HIV disease. All records and year of death, race, sex, age group, marital status and educational level of the person were considered. Results: In the 20 years studied, 232,274 deaths caused by the disease were recorded, an average of 11,613.7 (±1092.7) per year. White people represent 46.4%, followed by brown, 32.8%. Men are majority throughout the period, with 67.1% of records. People between 30 and 49 years old have the highest rates, 62.1% of deaths. Single people were majority, 61.1% of the total. As for education, people with up to 7 years of education correspond to 44% of deaths, while people with 12 years and more of education account for only 5.6%. Conclusions: White men, between 30 and 49 years old, single and with up to 7 years of schooling are, according to statistics, the most predisposed to die from the HIV disease. Especially from the data on education, it can be inferred that a higher level of education reduces the risks of death from the disease. Knowing this and the information about single people being more affected, the importance of sex education to early school years is recommended, as well as guidance in primary care.

  • A Systemic Review on the Pharmacognosy, Phytochemistry, Pharmacological and Clinical aspects of Edible stemmed vine, Cissus quadrangularis L

    Cissus quadrangularis Linn. belonging to the family Vitaceae is a common perennial climber, which is distributed throughout India. This square stemmed vine is widely used in traditional systems of medicines and parts like stem, roots and shoots are the most important parts, which are used medicinally. The article reveals a wide number of phytochemical constituents that had been isolated from the plant, which plays major role including gallic acid derivatives, steroids, iridoids, flavonoids, stilbenes and triterpenes, which possesses activities like anti inflammatory, anti tumor, gastro protective, antioxidant, antimicrobial and various other important medicinal properties. Many extensive research works had been done to prove its biological activities and pharmacology of its extracts. The current review deals with the enormous amount of updated information of scientific research and reports available in different aspects of this plant involving phytochemical, pharmacology, toxicological and clinical works. This review also includes reports on pharmacognosy, variants and traditional medicinal uses of the plant.

  • Clinical and Histopathological Findings in Patients with Follicular Dermatoses: All Skin Diseases Starts in the Hair Follicles as New Hypothesis

    Background: Follicular dermatoses are group of skin diseases characterised by follicular lesions during the course of the disease. Objective: To gather all skin diseases where there is follicular lesions to be evaluated in order to reach the hypothesis that hair follicles are the most principal target area in the etiopathogenesis of these skin disorders. Patients and Methods: This is a descriptive, clinical and histopathological study that was carried out at the Department of Dermatology, Baghdad Teaching Hospital, Medical City, and Baghdad, Iraq during the period from November 2018 to August 2019. Sixty patients with different follicular dermatoses were enrolled and all socio- demographic data related to the disease was obtained from each patient, in addition to physical examination was performed for each patient. Biopsies were taken from 40 patients, for histopathological evaluation. Results: Sixty patient, were included in this study, 35 patients males and 25 patients females with male to female ratio 1.4:1. Their ages ranged from 1-80(30.2 ± 16.96) years. All patients had follicular lesions. The histopathological results showed: perifollicular lymphocytes, follicular invasion and degeneration, follicular plugging, fibrous tract remnant, perifollicular melanophages and absent melanin pigment in the epidermis of patients with vitiligo. Conclusion: The result of the present study showed that all skin diseases start in the hair follicles and might spread to involve the proper epidermis, and the lesions could be microscopic or visible to the naked eye. The hair follicles have many anatomical and immunological privileges that make it easy to be an early target for any cutaneous pathological process. Hence these findings are in support of new hypothesis that say: all skin diseases starts in the hair follicles and then spread to attack the adjacent proper epidermis

  • Rising Incidence of Rubella among Patients With Febrile Rash Illness in a South Western State of Nigeria: a Ten Year Review

    Rubella infection is a differential diagnosis of febrile rash illnesses and its becoming more prevalent in countries yet to include Rubella containing vaccines into their routine immunization. It teratogenic effect in the first trimester of pregnancy is of public Health concern, hence this study aims to investigate the trend of Rubella infection in a Southwestern State of Nigeria over a ten-year period. A community based cross sectional retrospective study was conducted in all the 16 Local Government Areas and 177 wards of Ekiti state, using available records for Measles surveillance in the state. A review of the laboratory results of blood samples collected from all cases presenting with fever and maculopapular rashes in the state between 2010 and 2019 was done. Descriptive analysis of the data collected was done using SPSS version 22 and the results were presented in tables and charts. Level of statistical significance was set at p

  • Effectiveness and Safety of Apatinib Mesylate Tablet in the Treatment of Advanced Solid Tumors

    Angiogenesis is the most critical step in the development and progression of malignant tumors. Anti-tumor angiogenesis has become the most promising new strategy for tumor treatment. Rapidly growing tumor cells secrete a variety of vascular growth factors under hypoxia to stimulate tumor angiogenesis. One of the important growth factors is Vascular Endothelial Growth Factor (VEGF). Some small molecule compounds that inhibit VEGFR have been used to treat Tumors. In this study, we evaluated the effectiveness and safety of Apatinib Mesylate tablet in the treatment of advanced solid tumors. We found that Apatinib Mesylate tablet can treat advanced solid tumors.


    Introduction: In 2014, the Family Health Support Center participated in an event among children, adolescents with disabilities and their caregivers, where they receive treatment and follow-up at the Rehabilitation Center in the municipality of Messias, state of Alagoas. In this event, the mothers asked the professionals for individual and group care for them, justifying that the caregivers needed professional follow-up in the face of social and emotional overload. This year the nomenclature that was the group of mothers of children and adolescents with disabilities became a group of caregivers of people with disabilities opening inclusion for all caregivers in the municipality and also aiming at the reports of professionals from the Family Health Teams and the Center for Psychosocial Care who shared the concern with the increase in care for caregivers who have been getting ill mainly involving psychological issues. Objective: To develop actions that stimulate the strengthening and self-care in its biopsychosocial aspects, improving the quality of life and providing the consolidation of family affective bonds. Methods: This work is being carried out from the treatment of qualitative data, being an action research, descriptive and bibliographic, whose collection and collection of data occurred through conversation wheels and application of questionnaires, websites, journals and articles. Finally, it is of exploratory type, because it proceeds to provide greater familiarity with the problem that is established. Results: With the development of methods of Continuing and Permanent Education in Health, actions are practiced with strategies planned in the line of care, adding the support of the health care network so that it can be offered qualified and humanized services, thus improving the biopsychosocial and family aspects. Thus, it is remarkable that the objectives have been achieved according to shared reports and application of evaluation questionnaires in monthly meetings with caregivers. Conclusion: It is…


    Introduction: Belonging to sexual and gender minorities and being afro-descendent brings an intense burden to these individuals, because of the stigma strongly present in society. Therefore, it is necessary to practice activities that provide the well-being and quality of life, such as meditation. Objective: To report the experience of the extension project “The influence of the practice of meditation focusing on breathing in the signs and symptoms of anxiety in the afro-descendant LGBT population”, which was part of the “Nucleus of African-Brazilian Studies” of the University Federal de Alagoas. Methodology: This is a descriptive study, of the type of experience report. This extension project began in June 2018 and lasted until September 2019. The scholarship and collaborators were responsible for mediating the meditation meetings, which took place from Tuesday to Friday, both in the nursing school, as well as in the University Residence of the Federal University of Alagoas. Each participant was invited to attend a weekly meeting of meditation practice with focus on breathing, with three meditation blocks lasting 10min each, totaling 30min per meeting. In addition to the weekly meetings at the university, the participant received a meditation diary so that he could meditate daily at home, write down the difficulties encountered and the feelings experienced during the practice, in order to bring better results with the meditation routine. The research was approved by the Research Ethics Committee of the Federal University of Alagoas. Results: According to the records of the meditation practices made by the participants in the meditation diary, it was observed that, initially, they had a lot of difficulty in keeping the attention in breathing and other thoughts ended gaining space. However, with the course of the practices and the implementation of the meditative routine, there were feelings of lightness, tension relief, sleep improvement, concentration…