Recent Articles

INTRODUCTION- Anti-retroviral therapy is used for the treatment of patients with HIV. This therapy may also lead to some of the adverse drug reactions among which Zidovudine induced Buffalo Hump is an uncommon adverse drug reaction. CASE REPORT- In this present study a 38 year old women diagnosed with HIV disease in November 2008 and on ZLN therapy. By 2017 December she developed Buffalo Hump in her dorsal cervical area which was not associated with pain and erythema but discomfort is being observed. Patients was suggested for surgical removal of buffalo hump adipose tissue, but she refused to that. Later after six months of follow up the stabilization of fat in cervical region was observed. CONCLUSION- Protease inhibitors induced Buffalo hump is common but Ziduvudine induced Buffalo hump is uncommon. Treatment options include surgical removal of fat and exercise in order to maintain body fat.

The aim of study was to develop and evaluate microemulsion for permeation enhancement of Cumin in treatment of anaemia. Successful attempt was made to carry out formulation of Cumin loaded microemulsion. Oleic acid selected as oil phase, tween 80 and propylene glycol selected as surfactant and co-surfactant, from pseudoternary phase diagram different concentration of oil, surfactant, co-surfactant and distilled water were optimized and water dilution method was used for microemulsion preparation. Cumin extract loaded microemulsion were formulated and characterized for particle size, PDI, zeta potential, viscosity, percent transmittance, RI and drug content. The ex vivo permeation study was performed on goat small intestine. It was observed that 55.50% Cumin extract and 87.19% Cumin loaded microemulsion was permeated. This data indicates that Cumin loaded microemulsion has greater permeation as compared to extract. In vivo study data observed that microemulsion formulation increases the Hb, RBC, MCV, MCH, MCHC level as compared with extract. The results clearly indicate that microemulsion increases the Hb and RBC and bring towards the normal level.

Traditional medicine in Indonesia, especially broken bone massage, is usually done by experienced personnel or therapist whose got skills from their family or derived down from generation to generation since Dutch Colonial era. This study aims to find out about therapeutic communication process in traditional medicine, in this case, is broken bone massage. Therapeutic communication, in this case, is interpersonal communication with points of mutual understanding between therapist and patients. Fundamental issues and communication is the mutual need between therapist and patients so that it can be categorized into personal communication between the therapist and patients, therapist help and patients receive the help. The research method used is qualitative research. Qualitative research is a study aimed at understanding social reality, by seeing the world from what it is, not the world that should be, then a qualitative researcher must be people who have an open-minded nature. The informants in this study are a therapist and patients with the broken bone problem. This research data was obtained through observation, interview, and literature study. This paper discusses therapeutic communication process in traditional medicine between broken bone massage’s therapist and patients. The intention of this research is evidence how the process of therapeutic communication in traditional medicine gains patients trust and creating a sense of comfort while doing the treatment.

Compared with the common angle steel tower, the narrow base steel pipe tower has the advantages of simple structure, beautiful appearance, small floor area and better coordination with the urban environment. In the construction of urban high pressure transmission line, the narrow base tower has its own unique advantages and wide application prospects. It has the advantages of ordinary iron tower processing, transportation, assembly, cost saving, small occupancy of single column steel pipe rod, small line corridor and beautiful beauty. In the optimization design of the narrow tower, how to take the wind vibration coefficient of the tower, how to consider the bending moment of the rod end, the design of the narrow base tower and the structure optimization of the narrow tower tower are all the problems to be solved urgently. In this paper, the modal analysis of a single tower is carried out to determine its vibration mode, and then the wind vibration coefficient of a narrow tower is analyzed. Finally, the influence of x and y direction vibration on the frequency of the tower is obtained.

This paper focuses on the effect of MHD mixed convection flow of casson nanofluid past a stretching sheet in the presence of viscous dissipation, first order chemical reaction and heat source/sink. The profiles for the velocity, temperature and nanoparticle concentration depends on the parameters Casson fluid parameter β, concentration buoyancy parameter N, Hartman number M, radiation parameter R, Prandtl number Pr, the Schmidt number Sc, Brownian motion Nb, thermophoresis parameter Nt, Eckert number Ec, chemical reaction parameter γ the heat transfer Biot number γ1 and the mass transfer Biot number γ2. The constitute governing partial differential equation of flow, heat and mass transfer on considered flow are converted into nonlinear ordinary differential equations by employing suitable transformations and these transformed equations were solved by the Adam’s Moultan fourth order method with shooting technique. The various numerical tables are calculated and tabulated. Our results have been compared with the results of a previous study and found to be in an excellent agreement.

The main objective of the present work was to prepare pomegranate peel extract based nano particles by chemical complexation method. Ethanolic extracts of pomegranate peel were prepared by using Soxhlet apparatus and evaluated for phyto-chemical constituents. Qualitative analysis showed that pomegranate peel extract showed positive results for alkaloids, anthraquinones, saponins and terpenoids. The percentage moisture content and pH of the extract was found to be 72% and 3.6 respectively. A zeta potential and particle size of prepared nanoparticles was found in the range of -24.6 to– 34.5 mV and 118.6 nm to 231.7 nm, respectively. These range confirms that obtained particles were in nano range, i.e.

Importance: Non-healing diabetic ulcerations of the foot lead to amputations and premature mortality. Microburst Insulin Infusion has demonstrated an ability to accelerate healing in otherwise non-healing wounds. Objective: To demonstrate the benefit of adding Microburst Insulin Infusion to conventional diabetic wound care to significantly decrease wound healing time. Methods: A case series of five patients received Microburst Insulin Infusion therapy for significant peripheral diabetic ulcerations after failing conventional wound care. These five cases were treated from 4 independent Microburst Insulin Infusion clinics. Four of the wounds exceeded 6 cm². Patient charts were reviewed and relevant data was collected. All individuals in this manuscript have given written informed consent to publish these case details. Setting: Multicenter referral clinics providing Microburst Insulin Infusion Therapy Exposure: Microburst Insulin Infusion is an adjunctive treatment to conventional diabetic therapy performed in an outpatient clinic setting. A weight based oral glucose dose is administered while pulsatile intravenous insulin is delivered by the Bionica Microdose pump. The treatment is comprised of three 1 hour sessions and occurs up to five times a week, when the patient presents with un-healing wounds. Main Outcomes and Measures: Time to wound healing. A secondary outcome was failure of wound healing. Hypothesis for this study was formulated post treatment. Results: A significant decrease in wound healing time was observed when utilizing Microburst Insulin Infusion. The mean time to complete healing was 84.2 days compared to 133 days in published literature(1). The patient with a foot wound measuring an amazing 228.6 cm² healed in 102 days and amputation was not necessary. There were no treatment failures in this small series. As a result of decreased healing time, there was an absence of infection and no amputations were required for these wounds. Conclusion and Relevance: The addition of Microburst Insulin Infusion therapy resulted in…

A large-scale pot experiment was accomplished for investigation of the varied effects of different concentrations of Cu and Cd on certain growth and metabolic attributes of roots and shoots of Phaseolus vulgaris plants, over a period of three weeks. Plants supplemented with Cu and Cd at the concentrations of 10-6 and 10-3 M, showed increased levels of Cu and Cd in both shoots and roots, above those levels in controls. However, Cu or Cd accumulation was lower in shoots than in roots. As compared with control levels, the low (10-6 M) concentration of Cu induced either a significant or an insignificant increase in growth parameters, photosynthetic pigments, PS II activity, glucose, proline and glycine contents in both roots and shoots. Otherwise, insignificant decreases in fructose, sucrose, polysaccharides, total saccharides, total soluble-N, protein –N, DNA and RNA contents, in the same test plant parts, were obtained. A reverse situation was however observed with the high concentration (10-3 M) of Cu as well as with the low and high concentrations (10-3 and 10-6 M) of Cd. In general, the observed adverse effects were more pronounced with Cd at (10-6 M) as compared with those maintained with Cu at the same concentration. Furthermore, the most detrimental adverse effects were apparent upon administration of the high (10-3 M) concentration of Cd. The prominence of the above mentioned changes in growth and metabolism to stress tolerance in common bean is discussed.

The valuable functionalism appears as a strategy of achieving the working interaction between social sciences and humanities, and thus becomes paradigmatic value: in addition to developing its own epistemological perspective it offers a methodology and philosophy which enable new institutional perspective to develop a new type of single socio-humanitarian knowledge. Valuable functionalism is cognitive position and strategy of action, which asserts the values with help of their functional interpretation and implementation in certain behavior. Modern humanities needs to take into account the experience of the combination of value and functional aspects of a systematic approach in social cognition, which should be considered as a philosophical reflection of paradigmatic shift processes in modern social-humanitarian knowledge.

In the present study adsorption of copper (II) ions from aqueous solution by activated carbon was produced from cotton stalks husk via thermal pretreatment preceding chemical modification with phosphoric acid was investigated under batch mode. The biosorbent was characterized by thermo-gravimetric analysis, Fourier transform infrared (FT-IR) and iodine number. The influence of copper concentration, contact time, and temperature was studied. Sorption equilibrium time was observed in 30 min. The equilibrium adsorption data were correlated with Freundlich and Langmuir adsorption isotherm models. The kinetics of the adsorption process was tested by pseudo- first-order, pseudo-second order and Intra-particle diffusion. It was shown that adsorption of copper could be described by the pseudo-second order kinetic model. Thermodynamic parameters such as Gibbs free energy (∆G0), the enthalpy (∆H0) and the entropy change of sorption (∆S0) have also been evaluated and it has been found that the adsorption process was spontaneous, feasible and endothermic in nature. The results indicated that Activated carbon was produced from cotton stalks husk can be used as an effective and low-cost adsorbent to remove copper (II) from aqueous solution.