Giant hydronephrosis in an 82-year-old woman with multiple comorbidities: a case report
Giant hydronephrosis is a rare urinary tract disorder characterized by a collection arising from the kidney. Because of its complications, surgery remains the main treatment. Here we report the case of an 82-year-old woman with multiple comorbidities and diagnosis of giant hydronephrosis. After multidisciplinary concertation between urologists and geriatricians, no specific treatment was initiated. This case report highlights a non-specifically presentation of this rare disorder, including no symptom. The presence of multiple comorbidities has changed the management commonly reported in the literature.
Prostate stromal tumour: case reports and review of literature
Background Prostate cancer is a common malignancy in men; however, sarcoma of the prostate is an uncommon variant. Sarcoma of the prostate occurs in all age groups with rhabdomyosarcoma being more common in children while leiomyosarcoma occurs more in the older adults. Stromal tumour of uncertain malignant potential (STUMP) occurs in adults. Modalities of treatment include surgery, radiotherapy and chemotherapy used singly or in combination, but all report poor long term survival despite treatment selected. We present 2 cases of prostate stromal tumours. Case report We present two patients in their fourth decade who presented with acute urinary retention. Computed tomography scan was performed in both cases and showed a large tumour arising from the prostate. Prostate specific antigen was less than 4ng/ml in the two cases and core needle biopsy performed and samples taken for histology. The histology reports showed embryonal carcinoma and STUMP in the first and second cases respectively. Conclusion Prostate sarcomas are uncommon but may pursue aggressive clinical course while STUMP has a variable course. Early diagnosis and use of combined modalities of treatment may be required to improve survival.
Indigenous Suffering: Panorama of the Pandemic in the Pernambucan Community
Objectives: To present the current panorama of the distribution of cases of COVID-19 among the indigenous population in the state of Pernambuco. Methods: This is a retrospective study conducted on secondary electronic databases in the public domain, reflecting the exemption of appreciation by the Ethics Committee. The database consulted was of the Center for Strategic Information on Health Surveillance (CIEVS) in the State of Pernambuco. The reference period for collection was from April 1st to October 2nd, 2020. Epidemiological bulletins and virtual monitoring reports, available on the CIEVS website, were analyzed. The data were analyzed using descriptive statistical techniques based on obtaining absolute and percentage frequencies. Results: According to the last Census, Pernambuco corresponds to the 4th state with the largest self-declared indigenous population (53,284 people), with twelve ethnic groups spread across the statte territory. Related to the distribution of cases of infection by COVID-19, a data from the last Bulletin (No. 215/2020) indicated that among the most affected indigenous ethnic groups with confirmed cases, Funi-Ô stands out with 214 confirmed cases and five deaths while the Xucuru group had 110 confirmed cases and one registered death. Conclusion: The results showed that the CODIV-19 pandemic is a serious Public Health problem among the indigenous popultion of the state of Pernambuco. Thus, the responsibility of the state health management to define strategies that minimize the transmission of the disease in the indigenous population is reinforced, together with the development of health promotion and prevention and infection control actions.
Cases of sexual diseases with alpha-emitting nanoparticulates : Parkinson’s, Primary Biliary Cholangitis (prostate and clitoris) – and opening the breast implant debate
These diseases can be called sexual diseases thanks to retro-analysis of the global process of development and degenerescence and combination of the author’s earlier works with research of other authors that demonstrate in new ways the argument. Cultures that encourage sexual repression produce diseases mechanically and exogeneous factors of internal contamination with alpha emitters demultiplicate the effects spilling from these cultural choices. It is possible that researchers investigating Parkinson’s have already years ago understood the link with alpha decay and “flagged” it but because they thought that Parkinson patients had to suffer due to their full responsibility in depriving their own prostate whereas homosexuality shows how stimulating it creates well-known powerful orgasms went not beyond the allegory of alpha emitting nanoparticulates in their articles (which is why this is called “flagging” – “signaling”).
Ultrafiltration (UF) Effectiveness on intradialytic hypertension (IDH) in chronic hemodialysed patients in a nephrology unit in Dakar: UF-IDH clinical trial
Introduction Progressive ultrafiltration (UF) could improve IDH. The aim of this work was to evaluate the effectiveness of progressive UF in the management of IDH. Methods This randomized clinical trial in two groups: interventional group A (UF, n = 12) and control group B (n = 12), was conducted in chronic hemodialysis patients with IDH. A first phase of cross-sectional collection of BP before and after dialysis, during 2 weeks, made it possible to obtain this cohort of 24 patients. A progressive decrease in basal weight of 0.25 kg per session as a function of hemodynamic tolerance was achieved in group A. The primary endpoint, the proportion of patients with disappearance of IDH, was assessed at baseline end of the 4th and 8th week. Results At the 4th week, the IDH disappeared in 83.3% and 41.7% of the patients of the group A and B respectively with a hazard ratio (HR) at 0.29; IC 95 = [0.14-0.59]; p = 0.035. At the 8th week, the IDH was missing in 72.7% and 66.7% of the patients of the group A and B respectively with a HR at 0.76; IC 95 = [0.58-1.00]; p = 0.75. In addition, the decrease in basal weight was associated with the occurrence of side effects (p = 0.0001) with a HR of 5 [1.45-7.27]. UF discontinuation was required in 4 patients in group A (36.4%). Conclusion Progressive UF was associated with a significant reduction in the prevalence of IDH in our patients at week 4.
Research status and development direction of controlling factors of graphite mineralization in coal measures
Coal-measure graphite mineralization control is affected by many factors. In order to explore the ore-forming control factors and influence mechanism, the paper comprehensively analyzes the influence and mechanism of each factor from five aspects of coal rock composition, coal grade, temperature, pressure and mineralizer, combined with geological examples. The results show that in the process of graphite mineralization in coal measures, the components of coal and rock have the ability of graphitization, but the higher the degree of metamorphism of coal as carbon source, the higher the degree of graphitization of products, the higher the ore-forming temperature, and the higher the degree of graphitization. The development of tectonic movement promotes the graphitization, but the degree of graphitization is different and complicated due to the stress dissipation. Different minerals in coal have different effects on graphite mineralization in coal measures, and its mechanism needs to be further explored. Finally, it is pointed out that the research direction of coal series graphite lies in the different graphitization mechanism of the same rank coal and the different influence mechanism of different minerals in coal.
Nutritional potential of anti-anemic drinks based on Manihot esculenta L. or Graptophyllum pictum L. leaf extracts consumed in Yaoundé Cameroon
Anemia is a global public health problem. In Cameroon, the most vulnerable to anemia are children under 5 years of age (60%) and pregnant women (40%). To reduce prevalence of anemia, several approaches have been adopted, including promoting the production and consumption of iron-rich foods/products. The objective of this work was to study the nutritional potential of anti-anemic drinks based on extracts from the leaves of either Manihot esculenta or Graptophyllum pictum consumed by the populations of the city of Yaoundé in Cameroon. Macronutrient contents were determined using the standard A.O.A.C. methods, while mineral contents were analyzed using the atomic absorption spectrophotometry. Bioactive compounds such as total polyphenols, flavonoids, and saponins were analyzed. Vitamin C was determined by the 2,6 dichlorophenol indophenol spectrophotometric method (DCPIP) and the contents of anti-nutrients (tannins, phytates, oxalates, saponins, hydrocyanic acid) quantified using standard methods. The results of these analyses show that the mean protein contents in the studied anti-anemic drinks ranged from 0.64 ± 0.08 g/100 mL to 1.84 ± 0.02 g/100 mL (M. esculenta drink); and 0.25 ± 0.01 g/100 mL (G. pictum drink). Sugar contents ranged from 0.30 ± 0.02 g/100 mL to 0.45 ± 0.01 g/100 mL (M. esculenta drink), and 0.29 ± 0.01 g/100 mL (G. pictum drink). As concerns iron contents, and vitamin C contents were inversely proportional across M. esculenta drinks containing 25% milk (2.29 ± 0.15 mg/100 mL iron; 57.9 ± 0.2 mg/100mL vit C) through 50% milk (1.70 ± 0.03 mg/100 mL iron; 147.19 ± 16.05 mg/100 mL vit C) to 75% milk (1.01 ± 0.11 mg/100 mL iron; 221.1 ± 16.96 mg/100 mL vit C). Likewise, iron and vit C levels in the G. pictum drink were 0.18 ± 0.01 mg/100 mL and 999.1 ± 41.2 mg/100 mL respectively. In general, although some anti-nutrients were…
The predictive power of approach and autonomous goal motivation for work engagement among public sector employees
This paper compares the relative predictive power of approach goal motivation and autonomous goal motivation for work engagement among public sector employees. To do so, it employs the goal-striving reasons framework within which people’s approach goal motivation is measured as well as the self-concordance theory which measures people’s autonomous goal motivation. Findings are based on cross-sectional and longitudinal data of 132 public service employees at time 1 and 78 employees at time 2. Overall, the results show, using multiple regression analysis, that approach goal motivation significantly predicts work engagement whereas autonomous goal motivation is not a significant predictor of work engagement. On an individual goal-reason level, a similar picture emerges. Pleasure and altruism, the two approaching goal-striving reasons, are descriptively more strongly correlated with work engagement than their comparable self-concordance reason of intrinsic and identified goal motivation. When testing the predictive power of pleasure and altruism with intrinsic and identified goal motivation simultaneously, using multiple regression analysis, pleasure remains the only significant predictor of work engagement at time one and time two. The findings suggest that approach motivation is a stronger predictor of work engagement than autonomous goal motivation for public sector employees. Additionally, the findings also indicate that pleasure is more important for the work engagement of public sector employees than their altruistic goal motivation on an individual goal-reason level.
Risk assessment of Ordovician limestone water inrush in No.9 coal seam of Yangdong coal mine and its prevention and control measures
With the increasing of mining depth, intensity, scale and speed, Ordovician limestone water has become the biggest threat to the safety production of the low group seam. Based on the existing geological data, the hydrogeological characteristics of Ordovician limestone water are analyzed; the risk of Ordovician limestone water inrush is evaluated by using the method of “five maps and double coefficients” and considering the importance of effective protective thickness of floor protective layer in the evaluation results. The results show that there are no non straight through relative safety area (Area I) and non straight type relative risk area (Area II), only non straight type water inrush risk area (Area III) and straight through water inrush risk area (Area IV). According to the evaluation results, the floor grouting reinforcement is directly adopted in Area IV, and the Ordovician limestone may need to be modified in the strong water rich area; in Area III, the grouting transformation of the floor is carried out after the area with water inrush is identified first, but the Ordovician limestone is not needed. Other prevention and control measures should be subsidiary.
Social Media, Physical and Mental Health During a COVID-19 Lockdown
Social media including texting, internet use, and Facebook time have differential effects but those have not been studied during the social isolation of lockdowns when they might be more prevalent. In this Survey Monkey study, as many as 98% of 260 respondents reported texting, 100% using the internet, and 91% being on Facebook. The percentiles for those using the different media “a lot” were 45%, 77% and 42% respectively. Correlation analyses suggested that texting and internet use were positively related to Connecting Scale scores. However, internet use was also positively related to scores on Stress, Anxiety and Depression Scales and Facebook use was positively related to not only scores on Stress, Anxiety and Depression Scales but also to scores on Fatigue, Sleep Disturbance and PTSD scales. ANOVAS based on comparisons between groups reporting no to moderate use versus “a lot” of use were confirmatory of the correlation analyses. These results are limited by their being self-reported data from a non-representative, cross-sectional sample. Nonetheless, they highlight the positive and negative effects of different social media during a COVID-19 lockdown.