International Journal of Aging Research


Epithelial tissue response to pathological effects in various age groups. Participation of morphofunctional zones and Src-kinase in this process

Review Article of International Journal of Aging Research Epithelial tissue response to pathological effects in various age groups. Participation of morphofunctional zones and Src-kinase in this process Tatiana Yavisheva1*, PhD, ScD and Sergey Shcherbakov2, PhD, ScD 1,2JSC “R-Pharm”, scientific laboratory of mechanisms of stem cells regulation, Moscow, Russian Federation The response of human organism tissues to various pathological effects depends to a large extent on the presence of the total amount of key protein in the organism - Src-kinase and the ratio of its active part to inactive. With a sharp preponderance of an inactive portion of this protein over the active, the proliferative activity of cells is suppressed, and with a significant preponderance of the active part, proliferation is inadequately increased. The amount of this protein is embedded in embryogenesis and individually in each person. In the age aspect, a decrease in the Src-kinase content in the human organism is observed. The epithelial tissue of two age groups: 20-40 and 75 years and older responds most acutely to pathological effects, including the entering of viruses, since in 20-40 years the number of Src-kinase is the greatest in relation to other age groups, and in 75 years and older - the least, which causes a decrease in the reactivity of organism tissues or, conversely, hyperactivity. Keywords: Epithelial response; Labile groups 20-40 and 75 years and older; Pathological effects; Src-kinase ...

Older Adults’ Engagement in Mindfulness Practices

Research Article of International Journal of Aging Research Older Adults’ Engagement in Mindfulness Practices Neha Shivhare1, David Kaufman2 1City University of Seattle 2Simon Fraser University There is substantial evidence to suggest that mindfulness practices positively affect older adults’ physical, emotional, and cognitive wellbeing. However, there is still little information available about the interest and inclination among older adults for performing mindfulness-related exercises. We conducted a survey study aimed at exploring the prevalence of older adults engaged in such activities. Data were collected from 174 older adults (Males: 48; Females:126) who responded using a self-constructed survey, and analyzed using SPSS. Results indicate that almost two-thirds of older adult respondents engage in at least one mindfulness practice and almost a third engage in more than one, with meditation, deep breathing, and yoga being the most prevalent. Keywords: Older Adults’ Engagement; Mindfulness Practices ...

Potentially Inappropriate Medications for Older Adults in Dental Practice

Review Article of International Journal of Aging Research Potentially Inappropriate Medications for Older Adults in Dental Practice Anna Carolinne Santana Neves, Aurylanne Mikaelle Brandão Silva, José Monteiro dos Santos, Lara Rebelo de Almeida Residência Multiprofissional em Saúde, Universidade Federal de Pernambuco Objective: The present study aimed to review the medications frequently prescribed in dental practice that are potentially inappropriate for the elderly population due to the risks presented. Methods: An integrative literature review was carried out, based on the Guidance Manual: Prescription and Dispensing of Medicines Used in Dentistry, which reports the main drugs prescribed in dental practice (2017). From this, medications described in the Beers list of the American Society of Geriatrics (2019) were extracted, in order to identify medications that are potentially inappropriate in the elderly, what are the main consequences of use and appropriate management in view of the need for prescription. Results: The prescription and dispensing guidance manual for medicines used in dentistry has a list of 142 medicines, containing anti-inflammatories, antibacterials, opioids, benzodiazepines and other types of drugs. Of the drugs listed, 27 are considered inadequate and the most common therapeutic class among the drugs was anti-inflammatory drugs, being equivalent to 44.5% of the inadequacies found. Conclusion: Despite the risks associated with medications, it appears that they are widely prescribed in dental practice, making these groups worthy of special attention due to their potential for serious adverse events and negative impacts on the elderly and the health system, in addition to to emphasize the importance of the professional regarding the best indications and pharmacotherapeutic follow-up by the clinical pharmacist in caring for the elderly. Keywords: Dental Care for Aged, Pharmaceutical Preparations, Aged ...

The Usefulness of Short Physical Performance Battery Score for Predicting the Ability of Toilet Activity in Hospitalized Older Patients

Research Article of International Journal of Aging Research The Usefulness of Short Physical Performance Battery Score for Predicting the Ability of Toilet Activity in Hospitalized Older Patients Daisuke Takagi, PhD1*, Masatoshi Kageyama2,3, Kenta Yamamoto4, Hiroshi Matsumoto, MD5 1Department of Shizuoka Physical Therapy, Faculty of Health Science, Tokoha University. 2Long-Term Care Health Facilities Sunrise Ohama. 3Graduate School, Hamamatsu University School of Medicine, Cooperative Major in Medical Photonics (Doctoral Course). 4Department of Rehabilitation, Toyoda Eisei Hospital. 5Department of Orthopedic Surgery, Toyoda Eisei Hospital. Background: It has been still unclear whether the cut-off value of the short physical performance battery for predicting the ability of the toilet activity in the hospitalized older patients. The aim of this study was to reveal the relationship between the short physical performance battery and the ability of toilet activity, and also to determine the cut-off value of the short physical performance battery score for the ability of toilet activity in the hospitalized older patients. Methods: In this cross-sectional study, 71 hospitalized older patients were recruited. The short physical performance battery and the ability of toilet activity using the Barthel index (BI) were measured. The patients were split into two groups, according to the ability of toilet activity (Group 1: 10 point; Group 2: 5 point or less in BI score). A multiple logistic regression analysis was used to assess the relationship between the two groups. Moreover, the cut-off value for dividing into two groups, (Group 1 and Group 2) using the short physical performance battery score, which was calculated by a receiver operating characteristic curve. Results: The short physical performance battery score was an independent explanator for the ability of toilet activity using multiple logistic regression analysis. Besides, the cut-off value of the short physical performance battery for the ability of toilet activity was set in this ...

Dr. Jong In Kim
Professor and Chairman, Institute for Longevity Sciences, Wonkwang University, South Korea

Dr. Emmanuel ANDRES
Professor of Internal Medicine; Head of the Department of Internal Medicine, Internal Medicine in the University hospital of Strasbourg, University of Strasbourg, France

Dr. Karen V. Harper-Dorton
Professor, School of Social Work, West Virginia University, West Virginia 26506

Dr. Ferhan SOYUER
Professor, Nuh Naci Yazgan University Faculty of Health Sciences, Kayseri/Turkey

Dr. Akira Sugawara
Professor, Department of Molecular Endocrinology,Tohoku University Graduate School of Medicine, Miyagi, Japan

Dr. Francisco López-Muñoz

Professor of Pharmacology, Director of International Doctorate School, Chairman of the Research Ethics Committee, and Assistant Director of Academic Staff at Camilo José Cela University, and Research Fellow at “Hospital 12 de Octubre” Research Institute (Madrid, Spain), and Portucalense Institute of Neuropsychology and Cognitive and Behavioral Neurosciences (INPP), Universidade Portucalense Infante Dom Henrique 

Dr. Diego Lacono
Associate Professor, Biomedical Sciences, Biomedical Research Institute of New Jersey, NJ 07927

Dr. Ya-Lie Ku
Associate Professor, College of Nursing, Department of Nursing, Fooyin University

Dr. Dorina Lauritano
Assistant Professor, Faculty of Medicine – University of Milano”Bicocca”, Monza

Dr. Naohiro Hohashi
Professor, Division of Family Health Care Nursing, Department of Nursing, Graduate School of Health Sciences, Kobe University

Dr. Bechor Zvi Aminoff
Professor, Geriatric Division, The Chaim Sheba Medical Center, Tel Hashomer, Israel

Dr. Lia Ginaldi
Full Professor, Department of Clinical Medicine, Public Health, Life and Environment Sciences University of L’Aquila

Dr. Ufuk Çakatay
Professor, Department of Medical Biochemistry, Cerrahpaşa Faculty of Medicine, Istanbul University, Istanbul, Turkey

Dr. Fabio Monzani
Professor, Department of Clinical & Experimental Medicine, Section of Geriatrics and Gerontology, University Hospital of Pisa, Italy

Dr. Robert L. Clegg
Professor/Faculty Head, Health Administration Programs

Dr. Ian Martins
Centre of Excellence for Alzheimer’s Disease Research and Care Sarich Neuroscience Research Institute, Edith Cowan University, Australia

Dr. Kim L. Stansbury
Associate Professor/Director of MSW Program, Department of Social Work, North Carolina State University, Raleigh, North Carolina

Dr. Putilov, Arcady A.
Chief researcher, Research Institute for Molecular Biology and Biophysics, Novosibirsk, Russia

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1. Avinaba Mukherjee, Sourav Sikdar, Anisur Rahman Khuda-Bukhsh. Evaluation of ameliorative potential of isolated flavonol fractions from Thuja occidentalis in lung cancer cells and in Benzo(a) pyrene induced lung toxicity in mice. International Journal of Traditional and Complementary Medicine, 2016; 1(1): 0001-0013. 
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International Journal of Aging Research is a peer reviewed open access journal publishing research manuscripts, review articles, editorials, letters to the editor in Aging Research (Indexing details).

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