International Journal of Aging Research


Pharmacists in Aged Care Facilities

Review Article of International Journal of Aging Research Pharmacists in Aged Care Facilities Abdul Kader Mohiuddin Department of Pharmacy, World University of Bangladesh 151/8, Green Road, Dhanmondi, Dhaka – 1205, Bangladesh The expression “Home-based care” or basically home care might be characterized as a wide exhibit of various kinds of care gave in the home by a wide scope of gatherings. The continuum of various sorts of home-based care conveyed in the home shifts as far as various measurements, including sharpness, kind of care gave, and level of physician contribution. Home-based care incorporates both formal and casual individual care services, Medicare gifted home health, physician house calls, and even “emergency clinic at-home” services. Prescription related issues are essential among home care patients who take various drugs and have complex medical annals and medical issues. The destinations of home social protection organizations are to help individuals with improving limit and live with progressively noticeable opportunity; to propel the client’s optimal element of thriving; and to assist the patient with staying at home, keeping up a vital good way from hospitalization or admission to long haul care establishments. Home care is a game plan of care given by capable specialists to patients in their homes under the heading of a doctor. Home restorative services organizations join nursing care; physical, word related, and talk language treatment; and medical social organizations. Doctors may suggest patients for home therapeutic services organizations, or the organizations may be requested by relatives or patients. The extent of home human services benefits a patient can get at home is endless. Contingent upon the individual patient’s condition, care can reach out from nursing care to explicit medical organizations, for instance, research center workups. Essential investigations among home therapeutic services patients consolidate circulatory disease, coronary ailment, harm and hurting, musculoskeletal and ...

Primary Prevention of Alzheimer’s Disease in Indonesia

Research Article of International Journal of Aging Research Primary Prevention of Alzheimer's Disease in Indonesia Yuda Turana1, Jeslyn Tengkawan1, Ika Suswanti1, DY Suharya2, Woro Riyadina3, Julianti Pradono3 1Faculty of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia 2Alzheimer Disease International 3National Institute of Health Research and Development, Ministry of Health, Republic of Indonesia Indonesia is the fourth most populous country in the world. An increase number in the proportion of elders is accompanied by an increase of degenerative diseases and disabilities, including Alzheimer’s disease (AD). Prevalence of dementia in Indonesia is 1.2 million cases in 2015 and will keep increasing up to 3,980,000 in 2050. This study discusses data on the prevalence of dementia’s risk factors in Indonesia, calculates population-attributable risks (PAR) to identify the number of dementia cases that could be prevented, and determines which intervention strategies will have the most significant effect in reducing Alzheimer’s Disease (AD) cases. Prevalence of potentially modifiable risk factors for AD such as low education, hypertension, diabetes, obesity, and mental disorders are still high. Moreover, the prevalences keep increasing for the last five years. Low education has the highest estimated PAR, which could significantly lower new AD cases if it is being improved. Ten and thirty percent of risk factor reduction can decrease AD cases by 18,000 and 66,000 cases. In addition, reducing physical inactivity by 10% and 30% can reduce 19,000 and 55,000 cases of AD respectively; lowering 10% prevalence of midlife hypertension and diabetes can reduce 2400 and 1600 cases of AD. Decreasing 10% of all risk factors is estimated to reduce 22,000 of new AD cases. By reducing these modifiable risk factors, especially by improving access to education, the incidence of AD could be greatly reduced. This review is expected to give suggestion to the government in determining ...

Incidence of Cognitive Decline and Association with Changes in Sociodemographic, Lifestyle, and Health Indicators in Individuals aged 50 years and older: Prospective Cohort

Research Article of International Journal of Aging Research Incidence of Cognitive Decline and Association with Changes in Sociodemographic, Lifestyle, and Health Indicators in Individuals aged 50 years and older: Prospective Cohort Maria Cristina Umpierrez Vieira1, 2, Douglas Fernando Dias1, Maira Sayuri Sakay Bortoletto1, Ana Maria Rigo Silva1, Marcos Aparecido Sarria Cabrera*3 1Public Health Department, State University of Londrina (UEL), Londrina (Paraná), Brazil; 2Nursing Department, State University of the Midwest of Paraná (UNICENTRO), Guarapuava (Paraná), Brazil; 3Internal Medicine Department, State University of Londrina (UEL), Londrina (Parana), Brazil Objectives: To identify the incidence of cognitive decline (CD) in an urban community-dwelling population aged 50 years and older in a 4-year follow-up period and its prospective association with sociodemographic factors, lifestyle and health conditions as well as with changes in these factors. Methods: This is a prospective cohort with a representative sample of people aged 50 years and older (n = 206) from Cambé, PR, where baseline data collection occurred in the year 2011 and the follow-up occurred in 2015. The incidence of CD was the outcome of this study, and its evaluation occurred through the Mini-Mental State Examination. Results: The incidence of CD was 13.1% over the 4 years of follow-up, and adjusted Poisson regression models (sex, age and age range) showed that this condition was prospectively associated with depression (adjusted relative risk (RR) = 3, 50, 95% CI = 1.65-7.43). When analyzing the effect of sociodemographic factor changes on CD, it was verified that the risk of CD was 2.86 times higher among the group that stopped having a companion in the 4 years of follow-up when compared to the group that maintained a companion in that same period, independent of confounding factors. Conclusion: The data suggest that the CD process begins before the age of 60 y and that aggravation is ...

The Neuro Engraftment and Neuroregenerative effects of Hydrogen Sulphide Donor, Intracerebral MSCs, Ginko Biloba and Kefir in Attenuating Neuropathological hallmarks of Lipopolysaccharide induced Alzheimer’s disease Rat models

Research Article of International Journal of Aging Research The Neuro Engraftment and Neuroregenerative effects of Hydrogen Sulphide Donor, Intracerebral MSCs, Ginko Biloba and Kefir in Attenuating Neuropathological hallmarks of Lipopolysaccharide induced Alzheimer's disease Rat models Mai M.Anwar1, Ola S.M.Ali2, Laila A. Rashed.3, Badawi A.M.1, Nadia A.Eltablawy1 1Department of Biochemistry, National Organization for Drug Control and Research (NODCAR), Giza 12511, Egypt. 2Department of Biochemistry, Faculty of Pharmacy, Al-Azhar University, cairo 11311, Egypt. 3Department of Biochemistry and Molecular Biology, Faculty of Medicine, Cairo University, Giza 12511, Egypt. Background: Memory disorders have been characterized by being a devastating long term incurable diseases with a huge social impact in addition to a diminished efficient available medical treatments. Deep Brain stimulation via using neuroprotective inducers for treatment of brain structure degenerative diseases such as Alzheimer’s disease (AD) can be considered as being a promising successful therapy due to its various targets and underlying mechanisms for improving brain dysfunction. Objectives: The main aim of this study is to suggest therapeutic protocol having the potentials for restoring normal neurons diverse population and modifying neuropathological deposited hallmarks including both positive and negative lesions. Materials and Methods: Rats were divided into nine groups: (G1) control ;(G2) rats received LPS as a method of inducing nongenetically manipulated AD;(G3)AD rats received NaHS;(G4) AD rats received MSCs intracerebrally;(G5) AD rats received MSCs+NaHS;(G6)AD rats received kefir+GB;(G7)AD rats received MSCs+kefir+GB;(G8)AD rats received NaHS+kefir+GB; (G9) AD rats received MSCs+NaHS+kefir+GB. Results: AD induction resulted in down-regulation of CBS expression and GSH brain tissue level accompanied with overexpression in amyloid-β protein, MAPK, tau protein, ACAT expression and MDA brain tissue level in addition to elevated caspase-3 serum level. Conclusion: The implantation of amyloid reliving therapy that do have a wide clinical impact if initiated at benign plaques stage before irreversible brain damage occurs. The following effects have ...

Dr. Jong In Kim
Professor and Chairman, Institute for Longevity Sciences, Wonkwang University, South Korea

Dr. Emmanuel ANDRES
Professor of Internal Medicine; Head of the Department of Internal Medicine, Internal Medicine in the University hospital of Strasbourg, University of Strasbourg, France

Dr. Karen V. Harper-Dorton
Professor, School of Social Work, West Virginia University, West Virginia 26506

Dr. Ferhan SOYUER
Professor, Nuh Naci Yazgan University Faculty of Health Sciences, Kayseri/Turkey

Dr. Akira Sugawara
Professor, Department of Molecular Endocrinology,Tohoku University Graduate School of Medicine, Miyagi, Japan

Dr. Francisco López-Muñoz

Professor of Pharmacology, Director of International Doctorate School, Chairman of the Research Ethics Committee, and Assistant Director of Academic Staff at Camilo José Cela University, and Research Fellow at “Hospital 12 de Octubre” Research Institute (Madrid, Spain), and Portucalense Institute of Neuropsychology and Cognitive and Behavioral Neurosciences (INPP), Universidade Portucalense Infante Dom Henrique 

Dr. Diego Lacono
Associate Professor, Biomedical Sciences, Biomedical Research Institute of New Jersey, NJ 07927

Dr. Ya-Lie Ku
Associate Professor, College of Nursing, Department of Nursing, Fooyin University

Dr. Dorina Lauritano
Assistant Professor, Faculty of Medicine – University of Milano”Bicocca”, Monza

Dr. Naohiro Hohashi
Professor, Division of Family Health Care Nursing, Department of Nursing, Graduate School of Health Sciences, Kobe University

Dr. Bechor Zvi Aminoff
Professor, Geriatric Division, The Chaim Sheba Medical Center, Tel Hashomer, Israel

Dr. Lia Ginaldi
Full Professor, Department of Clinical Medicine, Public Health, Life and Environment Sciences University of L’Aquila

Dr. Ufuk Çakatay
Professor, Department of Medical Biochemistry, Cerrahpaşa Faculty of Medicine, Istanbul University, Istanbul, Turkey

Dr. Fabio Monzani
Professor, Department of Clinical & Experimental Medicine, Section of Geriatrics and Gerontology, University Hospital of Pisa, Italy

Dr. Robert L. Clegg
Professor/Faculty Head, Health Administration Programs

Dr. Ian Martins
Centre of Excellence for Alzheimer’s Disease Research and Care Sarich Neuroscience Research Institute, Edith Cowan University, Australia

Dr. Kim L. Stansbury
Associate Professor/Director of MSW Program, Department of Social Work, North Carolina State University, Raleigh, North Carolina

Dr. Putilov, Arcady A.
Chief researcher, Research Institute for Molecular Biology and Biophysics, Novosibirsk, Russia

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1. Avinaba Mukherjee, Sourav Sikdar, Anisur Rahman Khuda-Bukhsh. Evaluation of ameliorative potential of isolated flavonol fractions from Thuja occidentalis in lung cancer cells and in Benzo(a) pyrene induced lung toxicity in mice. International Journal of Traditional and Complementary Medicine, 2016; 1(1): 0001-0013. 
2. Vikas Gupta, Parveen Bansal, Junaid Niazi, Kamlesh Kohli, Pankaj Ghaiye. Anti-anxiety Activity of Citrus paradisi var. duncan Extracts in Swiss Albino Mice-A Preclinical Study. Journal of Herbal Medicine Research, 2016; 1(1): 0001-0006.

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International Journal of Aging Research is a peer reviewed open access journal publishing research manuscripts, review articles, editorials, letters to the editor in Aging Research (Indexing details).

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