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Modelling Predictors of Gambling Harms with Stochastic Search Variable Selection (SSVS)

Review Article of International Journal of Addiction Research and Therapy Modelling Predictors of Gambling Harms with Stochastic Search Variable Selection (SSVS) Alysha Cooper, Harvey H. C. Marmurek University of Guelph The purpose of the present study was to introduce stochastic search variable selection (SSVS) as a procedure to identify a subset of important predictors of gambling harm. The target set of predictors were dimensions of trait impulsivity, gambling cognitions, and gambling motivations. Five types of gambling harm (feeling one has a personal problem; social criticism; feeling guilt; health; and, financial) were measured by the Problem Gambling Severity Index. Casino patrons completed the measures. As a first step, we identified the significant predictors that would be included in modelling an aggregate harm score. The most important predictors, the cognition that one is not able to stop gambling, and the motivation to escape or avoid life stressors, were positively associated with overall harm. Two weaker, but statistically significant, predictors were negatively associated with harm: sensation-seeking and illusion of control. Although a perceived inability to stop gambling was the most important predictor of each individual harm, the pattern of predictors varied across harms. For example, sensation-seeking was an important predictor only for the belief that one has a gambling problem, and escape/avoidance motivation was strongly predictive of financial harm. The results suggest that primary interventions designed to mitigate harm should address the belief that the gambler is unable to stop gambling, and motivations related to escape/avoid life stressors. Other interventions would be tailored to the specific harms experience by the gambler. Keywords: Modelling Predictors, Gambling Harms, Stochastic Search Variable Selection (SSVS) ...

A Systemic Review on the Pharmacognosy, Phytochemistry, Pharmacological and Clinical aspects of Edible stemmed vine, Cissus quadrangularis L

Review Article of American Journal of Clinical Research and Reviews A Systemic Review on the Pharmacognosy, Phytochemistry, Pharmacological and Clinical aspects of Edible stemmed vine, Cissus quadrangularis L Anoop Austin Head - Research and Development Center, Cholayil Private Limited, # 31-A/24, 4th Cross Main road, SIDCO Industrial Estate (North Phase), Aavin Dairy road, Ambattur, Chennai - 600 098, Tamilnadu, India. Cissus quadrangularis Linn. belonging to the family Vitaceae is a common perennial climber, which is distributed throughout India. This square stemmed vine is widely used in traditional systems of medicines and parts like stem, roots and shoots are the most important parts, which are used medicinally. The article reveals a wide number of phytochemical constituents that had been isolated from the plant, which plays major role including gallic acid derivatives, steroids, iridoids, flavonoids, stilbenes and triterpenes, which possesses activities like anti inflammatory, anti tumor, gastro protective, antioxidant, antimicrobial and various other important medicinal properties. Many extensive research works had been done to prove its biological activities and pharmacology of its extracts. The current review deals with the enormous amount of updated information of scientific research and reports available in different aspects of this plant involving phytochemical, pharmacology, toxicological and clinical works. This review also includes reports on pharmacognosy, variants and traditional medicinal uses of the plant. Keywords:  Cissus quadrangularis; Vitis quadrangularis; Vitaceae; Bone Fracture; Edible stemmed vine ...

The Use of a Rapid Fluid Infusion System in Children

Research Article of International Journal of Pediatric Research and Reviews The Use of a Rapid Fluid Infusion System in Children Sai Surapa Raju, MD1; Judy Fuller, RN2; Stacy L. Gaither, MSN, RN1; Hui-Chien Kuo, MS3; Inmaculada Aban, PhD3; Nancy M. Tofil, MD, MEd1 1University of Alabama at Birmingham, Department of Pediatrics 2Children’s Hospital of Alabama, Emergency Department 3University of Alabama at Birmingham, Pediatric Research Office Fluid resuscitation is the cornerstone of treatment for pediatric shock caused by conditions such as sepsis, dehydration, trauma, and anaphylaxis. Children presenting to the Emergency Department (ED) in shock have a high risk of mortality, and each hour of delay in shock reversal doubles the odds of death1,2. Pediatric Advanced Life Support (PALS) guidelines emphasize the importance of providing rapid fluid resuscitation to prevent the progression to hypotensive or refractory shock3. PALS and other septic shock guidelines recommend that patients receive a 20 mL/kg bolus of crystalloid immediately upon recognition of hypovolemic or distributive shock, with 20 mL/kg to be delivered within 5 minutes and up to 60 mL/kg within the first 15-60 minutes3-6. Studies based on these guidelines show that earlier fluid delivery directed at reversal of shock reversal leads to decreased morbidity7-9, mortality2,7,9-12, and hospital length of stay (LOS)9,11-13.  Unfortunately, timely fluid delivery is often not achieved due to the technical challenges of obtaining adequate vascular access and delivering fluid boluses quickly in patients with shock or hypotension11,14-16. Current methods of fluid bolus delivery in the pediatric emergency care setting include infusion pumps, gravity drip, pressure bags, rapid infusers, and the push-pull syringe technique17,18. Each of these methods are limited by speed, ease of use, or safety concerns. Infusion pumps provide a maximum rate of 999 mL per hour, which for a 25kg child would provide a 60 mL/kg bolus in 90 minutes ...

Logical Beauty Harmony and Natural Shape zones (NSz)

Case Report of International Journal of Case Reports Logical Beauty Harmony and Natural Shape zones (NSz) Noviello S, Gritzalas K, Maroni A, Tocchio M, Cogliandro G, Di Benedetto N Sergio Noviello Academy, Milano Estetica - Cosmetic Surgery Center - Milan - Italy The concept of beauty in the world is certainly influenced by ethnicity and cultural factors, but generally harmony, balance and simmetry are common characteristics positively considered by every population. Logical Beauty Harmony is an innovative System for using filler and botulinum toxin in aesthetic medicine based on Natural Shape zones (NS zones). These compartment consist of strategic sequential injection areas that allow creating, improving or restoring adequate volumes, guaranteeing natural results and expressiveness. Starting from the recent acquisitions of Functional Anatomy, Physiology of Aging, Product Rheology and considering the objective analysis of the characteristics of harmony of each individual we have developed an approach that uses injectables in a targeted way using Support and Lifting vectors at the level of Upper, Middle and Lower Third of the face, injecting first deep and then passing to the surface. The face is divided into vertical and horizontal proportions. These simply but fundamental principle of facial proportion, modified by recent anthropometric studies, have found their way into the teaching and practice of cosmetic facial medicine and surgery. The series of data that can be detected by applying the previous parameters offers the chance of identify the variants that the face can present, so as to make eventually those changes that lead closer to the ideal model. In planning the treatment, the study of the different parameters, proportions, lines, ideal movements and angles linked to the comparison of the measurements of the different parts of the face will be more useful in determining type and extent of the corrections to be made. 9 ...

A rare case of Pleuroparenchymal fibroelastosis in Sri Lanka

Case Report of International Journal of Case Reports A rare case of Pleuroparenchymal fibroelastosis in Sri Lanka Prasanjanie A. Jayasinghe, Ruwanthi Jayasekara, Amitha Fernando National Hospital of Srilanka. Pleuroparenchymal fibroelastosis (PPFE) is a very rare interstitial lung disease which carries many challenges in the process of diagnosis. A 73 years old female was evaluated for exertional dyspnea with CXR PA evidence of bilateral upper lobe fibrosis and pleural thickening. HRCT revealed typical features suggestive of PPFE. Lung biopsy was not performed considering the risk. Though it is rare PPFE should be considered when evaluating bilateral apical fibrosis. Proper radiological evaluation is paramount important in the process of diagnostic evaluation. Performance of lung biopsy as an essential criterion should be reconsider with associated risks. Keywords: Pleuroparenchymal fibroelastosis, Sri Lanka ...

Endoscopic Outcome of non complicated Gastric Ulcer following Standard Medical Treatment in sub-Saharan African Population

Research Article of Open Journal of Gastroenterology and Hepatology Endoscopic Outcome of non complicated Gastric Ulcer following Standard Medical Treatment in sub-Saharan African Population Kowo MP1, Essouma M1, Ndjitoyap Ndam AW1, Wembe Sop BD2, Kenfack GU1, Guekam Ouamba P2, Ndjitoyap Ndam EC1, Njoya O1, Ankouane Andoulo F1 1Faculty of Medicine and Biomedical Sciences, University of Yaounde I, Cameroon; 2Université des Montagnes Banganté Cameroon Background.The endoscopic outcome of gastric ulcers is not well described in sub-Saharan Africa. This study was therefore conducted in order to track the endoscopic outcome of non complicated gastric ulcers following standard medical treatment in  sub-Saharan African population. Methods.This was a prospective cohort study conducted from January to July 2018 in three tertiary healthcare centers in Yaounde (Cameroon).Gastric ulcers and gastric H. pylori infection were diagnosed and monitored by upper digestive endoscopy performed before and at least four weeks following treatment with proton pump inhibitors alone or combined with antibiotics depending on H. pylori status.  A complete case analysis was done using the SPSS software, version 21.0. p-values ≤0.05 were considered as significant. Results. Ninety-six patients (54.2% males) with a mean age of 55.3 ± 14.9 years were initially enrolled. In most patients, the ulcer frequently was unique (76%) and the antrum was the commonest localization 76 (79.2%). Among patients with H. pylori infection, the quadruple therapy was the most prescribed treatment 41 (87.2%) patients. There were 60 (62.5%) subjects lost to follow-up. Of the 36 (37.5%) patients who underwent repeat endoscopy, 26 (72.2%) had ulcer healing and 8/13 patients had successful H. pylori eradication. A delay of repeat endoscopy >8 weeks was the only predictor of non-healing of the ulcer: relative risk 0.6[95% CI: 0.3-1.08], p = 0.05. Conclusion.Ulcer healing was found in nearly 2/3 of patients and H. pylori eradication in almost ¾ of patients. This study ...