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Non-alcoholic Fatty Liver Disease among patients with Inflammatory Bowel Disease in Qatar: Prevalence and Risk Factors

Research Article of Open Journal of Gastroenterology and Hepatology Non-alcoholic Fatty Liver Disease among patients with Inflammatory Bowel Disease in Qatar: Prevalence and Risk Factors Dr. Muneera Al-Mohannadi1, Dr. Prem Chandra2, Dr. Betsy Varughese1, Dr. Abdulwahab Hamid1, Dr. Ahmed Badi1, Dr. Saad Al Kaabi1, Dr. Rafie Yakoob1, Dr. Khalid Al-Ejji1, Dr. Khaleel Sultan1, Dr. Adham A. H. Darweesh3, Nevin Abunahia1 and Dr. Moutaz Derbala4 1Gastroenterology & Hepatology, Hamad Medical Corporation, 2Research Affairs, Hamad Medical Corporation, 3Radiology, Hamad Medical Corporation, 4Prof., Hamad Medical Corporation, Doha. Qatar. Background: Non-alcoholic fatty liver disease (NAFLD) has been increasingly identified in patients with inflammatory bowel disease (IBD), though metabolic risk factors for NAFLD are less frequent in IBD patients. Qatar is among countries characterized by the high prevalence of fatty liver. We aimed to characterize NAFLD in IBD patients and to determine factors associated with its severity. Methods: A retrospective observational study was conducted to estimate the prevalence of NAFLD in all IBD patients followed at Hamad hospital, Doha, Qatar between January 2008 to December 2017. The associations between two or more qualitative variables were assessed using χ2-test and quantitative data between two independent groups were analyzed using the unpaired t-test. Multivariate logistic regression analysis was applied to determine the predictive values of each predictor for NAFLD among IBD patients. Results: Among 913 IBD patients with a mean age of 36.9±13.2 years and BMI 26.9±6.1; 550 were males (60.2%), 383(41.9%) with Crohn’s disease and 530 (58.1%) with Ulcerative colitis. 24 (22.2%) patients had severe steatosis. The overall prevalence of NAFLD was 11.8% (95% CI 9.9, 14.1) and does not differ significantly between CD and UC patients (11.7% vs 11.9%; P=0.949).Patients who developed NAFLD were older at baseline (42.6±12.5 vs 36.2±13.1 years; P<0.001), had higher BMI (29.3±5.7 vs 26.6±6.1; P<0.001) and higher prevalence of diabetes (26% ...

Recurrent Post-Cardioversion Takotsubo Syndrome

Case Report of International Journal of Case Reports Recurrent Post-Cardioversion Takotsubo Syndrome Jean Paul Mangion1, Geoffrey Horlait1 1Intensive Care Unit, Université Catholique de Louvain, CHU UCL Namur, Avenue Gaston Therasse, 1, 5530 Yvoir Belgium. Takotsubo syndrome (TTS) is characterised by transient regional wall motion abnormalities of the left or right ventricles often associated with new ECG changes (including ST-segment elevations, ST-segment depressions, T-wave inversions and QTc prolongation) in the absence of a culprit atherosclerotic artery which could explain the ventricular dysfunction. In this article we present an unusual case of recurrent TTS following electrical cardioversion in a 61 year old female patient who was admitted to our unit. Keywords: TTS; ECG ...

Sharing Stories as Legacy: What Matters to Older Adults?

Research Article of International Journal of Aging Research Sharing Stories as Legacy: What Matters to Older Adults? Neha Shivhare, Ph.D.1, Luciane Maria Fadel, Ph.D.2, David Kaufman, Ed.D.3 1Dayalbagh Educational Inst. (Deemed University), Agra, India. 2Federal University of Santa Catarina, Brazil. 3Simon Fraser University, Burnaby, Canada. Objectives: Legacy allows individuals to make meaning of their lives by passing on their experiences and beliefs to younger people and influencing their perspectives, perceptions, and actions. This mixed-methods study investigated: (1) What is important for older adults to share as legacy with families, friends and others, based on the types and features of their digital stories ? and (2) How do older adults’ digital stories affect story viewers? Methods: One hundred adults aged between 55 and 95 years participated in ten-week Elder’s Digital Storytelling courses and created short digital stories. Using the content analysis approach, the story transcripts were thematically analyzed and iteratively coded by three researchers and the results were quantified. A diverse group of 60 viewers at a public event provided their reactions to the digital stories. Results: The findings revealed that character, place, and family were chosen as the primary types by the older adults for their legacy digital stories. Accomplishment and career/school were the next most prominent story types. Moreover, these digital stories appeared to have a powerful impact on the viewers. Discussion: A digital story is a powerful artifact to communicate an older person’s legacy because it is based on familiar forms of communication, such as speech and photographs. The major legacy themes chosen by the older adults align with the findings of the research literature. The feedback from the viewers of the digital stories reflects these as a source of life wisdom and legacy for younger generations. Funding details: This work was supported by the AGE-WELL National Centre ...

Metastatic bladder tumor from pancreatic adenocarcinoma

Case Report of International Journal of Case Reports Metastatic bladder tumor from pancreatic adenocarcinoma Konstantinos M. Skrepetis1, Ioannis Efthimiou1, Zacharias Chousianitis1, Stavros Peroukidis1 1Department of Urology, General Hospital of Messinia, Kalamata, Greece. Metastatic pancreatic adenocarcinoma to the urinary bladder is extremely rare and has only been reported 4 cases worldwide. We describe such a case presented with hematuria and dysuria after ten months of the initial diagnosis. Immunohistochemistry helped to confirm the diagnosis of metachronous metastasis. Six months after being diagnosed with the bladder metastasis, progression with severe right hydronephrosis and mild dilatation of the left pyelocaliceal system palliated with an UventaTM metallic ureteral stent and a double J ureteric catheter. Keywords: Metastasis; Pancreas; Bladder; Hydronephrosis ...

Nutritional Potential of Some Invasive Species of Macaronesia for Ruminants

Research Article of American Journal of Agricultural Research Nutritional Potential of Some Invasive Species of Macaronesia for Ruminants C.S.A.M. Maduro Dias, C.F.M. Vouzela, H.J.D. Rosa, J.S. Madruga and A.E.S. Borba University of the Azores, Faculty of Agricultural and Environmental Sciences, Institute of Agricultural and Environmental Research and Technology (IITAA). Rua Capitão João d’Ávila, 9700-042 Angra do Heroísmo, Açores, Portugal. Macaronesia islands’ invasive plant use in animal feed or composting may bring economic and environmental benefits to the region. Arundo donax, Pennisetum setaceum, Agave americana, and Ricinus communis, present in the three archipelagos (Canary, Azores and Madeira), were characterized chemically and biologically. A. donax and P. setaceum showed elevated crude protein (CP) content, 13.25 and 16.33 DM%, respectively, and extremely high NDF values, 75.87 and 80.83 DM%, with a DM digestibility of 55.02 to 59.77%. A. americana showed a low NDF value (22.78 to 27.94 DM%) and a very low CP value (4.24 to 5.61 DM%). However, its DM digestibility was high (79.89 to 86.33%). R. communis presented the best values for CP (24.62%) and NDF (26.56 DM%), however, due to the presence of toxic substances (ricin), it cannot be easily used in animal feed. The P. setaceum and R. communis were found to be the least gas-producing forage, with A. americana being the major producer. To increase these plants’ value for animal feed, treatment with urea or NaOH to A. donax and P. setaceum, and enrichment with nitrogen to Agave is proposed. Due to its toxic properties, R. communis must be used in composting. This work has been funded by Ecofibras Project (MAC/4.6d/040) and INV2MAC project (MAC2/4.6d/229), and by FEDER funds via Operational Programme Competitiveness Factors– COM-PETE and by Regional Funds from Secretaria Regional do Mar, Ciência e Tecnologia. Keywords: Invasive plants; Nutritive valorisation; Composting; Macaronesia ...

Priapism as A Warning Sign for Chronic Myeloid Leukemia

Case Report of International Journal of Case Reports Priapism as A Warning Sign for Chronic Myeloid Leukemia Boudreaux, J, BS, BA1, Haller, CN, MD2, Maslov, D, MD, MS1,2, Bateman, L, MD2 1University of Queensland/Ochsner Clinical School, New Orleans, LA. 2Ochsner Clinic Foundation, Department of Internal Medicine, New Orleans, LA. CML is a chronic myeloproliferative disorder associated with activating mutations in tyrosine kinases forming a BCR-ABL fusion gene, causing hyperproliferation of neoplastic myeloid progenitors [1,2]. The incidence of CML peaks in the fourth and fifth decades of life [3]. In the United States, nearly 4,500 cases are diagnosed annually [3]. The onset of the disease is insidious due to the nonspecific initial “B symptoms,” such as increased fatigability, weight loss and weakness. The natural history of CML is slow with a median survival of three years if untreated [3,4]. The current treatment is targeted therapies to the BCR-ABL tyrosine kinase using imatinib or nilotinib and hydroxyurea. Although B symptoms are common, priapism can be an initial presentation of CML in 1-5% of cases [5]. Priapism is a urological emergency defined by a sustained erection of four or more hours. Hyperviscous blood in leukemias, such as CML, prevents appropriate venous drainage of the corpora cavernosa, resulting in failure of detumescence [4]. This case reports highlights priapism as a presenting sign of CML and reviews the pathophysiology between the association. Keywords: Chronic myeloid leukemia; Priapism ...